{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T12:16:48Z","timestamp":1768565808977,"version":"3.49.0"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Interventions"],"published-print":{"date-parts":[[2020,2]]},"abstract":"<jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Direct stenting without pre-dilation or post-dilation has been advocated for saphenous vein graft percutaneous coronary intervention to decrease the incidence of distal embolization, periprocedural myocardial infarction, and target lesion revascularization.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>We performed a post hoc analysis of patients enrolled in the DIVA (Drug-Eluting Stents Versus Bare Metal Stents in Saphenous Vein Graft Angioplasty; NCT 01121224) prospective, double-blind, randomized controlled trial. Patients were stratified into stent-only and balloon-stent groups. Primary end point was 12-month incidence of target vessel failure (defined as the composite of cardiac death, target vessel myocardial infarction, or target vessel revascularization). Secondary end points included all-cause death, stent thrombosis, myocardial infarction, and target lesion revascularization during follow-up.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>\n              Of the 575 patients included in this substudy, 185 (32%) patients underwent stent-only percutaneous coronary intervention. Patients in the stent-only versus balloon-stent group had similar baseline characteristics and similar incidence of target vessel failure at 12-months (15% versus 19%; hazard ratio, 1.34 [95% CI, 0.86\u20132.08];\n              <jats:italic>P<\/jats:italic>\n              =0.19). During long-term follow-up (median of 2.7 years), the incidence of definite stent thrombosis (1% versus 5%; hazard ratio, 9.20 [95% CI, 1.23\u201368.92];\n              <jats:italic>P<\/jats:italic>\n              =0.0085), the composite of definite or probable stent thrombosis (5% versus 11%; hazard ratio, 2.52 [95% CI, 1.23\u20135.18];\n              <jats:italic>P<\/jats:italic>\n              =0.009), and target vessel myocardial infarction (8% versus 14%; hazard ratio, 1.92 [95% CI, 1.08\u20133.40];\n              <jats:italic>P<\/jats:italic>\n              =0.023) was lower in the stent-only group. Multivariable analysis showed that a higher number of years since coronary artery bypass grafting and &gt;1 target saphenous vein graft lesions were associated with increased target vessel failure during entire follow-up, while preintervention Thrombolysis in Myocardial Infarction-3 flow was protective.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>In patients undergoing percutaneous coronary intervention of de novo saphenous vein graft lesions, there was no difference in target vessel failure at 12 months and long-term follow-up in the stent-only versus the balloon-stent group; however, the incidence of stent thrombosis was lower in the stent-only group, as was target vessel myocardial infarction.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Registration:<\/jats:title>\n            <jats:p>\n              URL:\n              <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.clinicaltrials.gov\">https:\/\/www.clinicaltrials.gov<\/jats:ext-link>\n              . Unique identifier: NCT 01121224.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circinterventions.119.008494","type":"journal-article","created":{"date-parts":[[2020,2,5]],"date-time":"2020-02-05T10:00:18Z","timestamp":1580896818000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":16,"title":["Stent-Only Versus Adjunctive Balloon Angioplasty Approach for Saphenous Vein Graft Percutaneous Coronary Intervention"],"prefix":"10.1161","volume":"13","author":[{"given":"Faisal","family":"Latif","sequence":"first","affiliation":[{"name":"VA Medical Center, Oklahoma City (F.L.)."},{"name":"University of Oklahoma, Oklahoma City (F.L.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren","family":"Uyeda","sequence":"additional","affiliation":[{"name":"VA Cooperative Studies Program Coordinating Center, Mountain View, CA (L.U., R.E., M.-C.S.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Edson","sequence":"additional","affiliation":[{"name":"VA Cooperative Studies Program Coordinating Center, Mountain View, CA (L.U., R.E., M.-C.S.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepak L.","family":"Bhatt","sequence":"additional","affiliation":[{"name":"VA Boston Healthcare System, MA (D.L., S.K., R.S.V)."},{"name":"Brigham and Women\u2019s Hospital Heart &amp; Vascular Center, Boston, MA (D.L.B.)."},{"name":"Harvard Medical School, Boston, MA (D.L.B.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Goldman","sequence":"additional","affiliation":[{"name":"University of Arizona Sarver Heart Center, Tucson (S.G.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"David R.","family":"Holmes","sequence":"additional","affiliation":[{"name":"Mayo Clinic, Rochester, MN (D.R.H.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sunil V.","family":"Rao","sequence":"additional","affiliation":[{"name":"Durham VA Medical Center, NC (S.V.R.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kendrick","family":"Shunk","sequence":"additional","affiliation":[{"name":"San Francisco VA Medical Center, CA (K.S.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kul","family":"Aggarwal","sequence":"additional","affiliation":[{"name":"Harry S Truman VA Hospital, Columbia, MO (K.A.)."},{"name":"University of Missouri Healthcare, Columbia (K.A.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barry","family":"Uretsky","sequence":"additional","affiliation":[{"name":"Central Arkansas Veterans Health System, Little Rock (B.U.)."},{"name":"University of Arkansas for Medical Sciences, Little Rock (B.U.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Islam","family":"Bolad","sequence":"additional","affiliation":[{"name":"Indiana University School of Medicine, Indianapolis (I.B.)."},{"name":"Roudebush VA Medical Center, Indianapolis, Indiana (I.B.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khaled","family":"Ziada","sequence":"additional","affiliation":[{"name":"University of Kentucky, Lexington (K.Z.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward","family":"McFalls","sequence":"additional","affiliation":[{"name":"VA Medical Center, Minneapolis, MN (E.M.)."},{"name":"University of Minnesota, Minneapolis (E.M.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anand","family":"Irimpen","sequence":"additional","affiliation":[{"name":"Southeast Louisiana Veterans Health Care System, New Orleans (A.I.)."},{"name":"Tulane University Heart and Vascular Institute, New Orleans, LA (A.I.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huu Tam","family":"Truong","sequence":"additional","affiliation":[{"name":"VA Loma Linda Medical Center, CA (H.T.T.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott","family":"Kinlay","sequence":"additional","affiliation":[{"name":"VA Cooperative Studies Program Coordinating Center, Mountain View, CA (L.U., R.E., M.-C.S.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasilios","family":"Papademetriou","sequence":"additional","affiliation":[{"name":"VA Medical center Washington DC (V.P.)."},{"name":"Georgetown University, Washington DC (V.P.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raghava S.","family":"Velagaleti","sequence":"additional","affiliation":[{"name":"VA Boston Healthcare System, MA (D.L., S.K., R.S.V)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bavana V.","family":"Rangan","sequence":"additional","affiliation":[{"name":"Minneapolis Heart Institute Foundation, MN (B.V.R., E.S.B.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kreton","family":"Mavromatis","sequence":"additional","affiliation":[{"name":"Atlanta VA Healthcare System, GA (K.M.)."},{"name":"Emory University, Atlanta, GA (K.M.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mei-Chiung","family":"Shih","sequence":"additional","affiliation":[{"name":"VA Cooperative Studies Program Coordinating Center, Mountain View, CA (L.U., R.E., M.-C.S.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Subhash","family":"Banerjee","sequence":"additional","affiliation":[{"name":"Dallas VA Medical Center, TX (S.B.)."},{"name":"University of Texas Southwestern Medical Center, Dallas (S.B.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emmanouil S.","family":"Brilakis","sequence":"additional","affiliation":[{"name":"Minneapolis Heart Institute Foundation, MN (B.V.R., E.S.B.)."},{"name":"Minneapolis Heart Institute, MN (E.S.B.)."},{"name":"Abbott Northwestern Hospital, Minneapolis, MN (E.S.B.)."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2010.07.009"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2001.117778"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.1258"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.100.24.2400"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(03)00309-0"},{"key":"e_1_3_4_7_2","first-page":"115","article-title":"Direct stenting may limit myocardial injury during percutaneous coronary intervention.","volume":"15","author":"Nageh T","year":"2003","unstructured":"Nageh, T, Thomas, MR, 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