{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T15:44:29Z","timestamp":1790610269986,"version":"4.1.0"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Interventions"],"published-print":{"date-parts":[[2020,7]]},"abstract":"<jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Coronary artery disease and aortic stenosis often coexist. Transcatheter aortic valve implantation (TAVI) has emerged as a valid therapeutic option for younger, lower-risk patients who may eventually require coronary artery disease treatment. Thus, post-TAVI coronary access (CA) and percutaneous coronary intervention are expected to increase. The purpose of this study was to retrospectively evaluate patients who were enrolled in the SOURCE 3 (SAPIEN 3 Aortic Bioprosthesis European Outcome) European registry for treatment with the balloon-expandable SAPIEN 3 transcatheter heart valve and underwent CA with or without percutaneous coronary intervention after TAVI.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>Baseline characteristics and clinical outcomes of patients with or without CA up to 3 years after TAVI were compared. A Kaplan-Meier estimate with a univariate model determined the impact of CA on cardiac mortality.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>\n              Of 1936 TAVI patients (mean age 81.6 years, 52% male), 68 (3.5%) had CA within 3 years (mean 441\u00b1332 days) after TAVI. At baseline, the logistic EuroSCORE was similar (20.2% versus 18.3%,\n              <jats:italic>P<\/jats:italic>\n              =0.2, CA and non-CA groups, respectively). Higher rates of coronary artery disease (76.5% versus 50.6%,\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001), myocardial infarction (20.6% versus 11.5%,\n              <jats:italic>P<\/jats:italic>\n              =0.03) and previous coronary artery bypass graft (22.1% versus 11.0%,\n              <jats:italic>P<\/jats:italic>\n              =0.01) were present in the CA group. In 100% of patients, CA was successfully achieved. The clinical success of percutaneous coronary intervention was 97.9%. Cardiovascular mortality was numerically higher in patients with CA than in those without CA.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>In the large SOURCE 3 European registry, CA was needed at 3-year follow-up after TAVI with a balloon-expandable valve in 3.5% of patients and was successful in all patients. The clinical success of percutaneous coronary intervention was 97.9%.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Registration:<\/jats:title>\n            <jats:p>\n              URL:\n              <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.clinicaltrials.gov\">https:\/\/www.clinicaltrials.gov<\/jats:ext-link>\n              . Unique identifier: NCT02698956.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circinterventions.120.008972","type":"journal-article","created":{"date-parts":[[2020,6,25]],"date-time":"2020-06-25T09:00:16Z","timestamp":1593075616000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":42,"title":["Coronary Access and Percutaneous Coronary Intervention Up to 3 Years After Transcatheter Aortic Valve Implantation With a Balloon-Expandable Valve"],"prefix":"10.1161","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5055-2917","authenticated-orcid":false,"given":"Giuseppe","family":"Tarantini","sequence":"first","affiliation":[{"name":"Cardiology Clinic, Department of Cardiac, Thoracic, and Vascular Sciences and Public Health Padova, University of Padua, Italy (G.T., L.N.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5823-2088","authenticated-orcid":false,"given":"Luca","family":"Nai Fovino","sequence":"additional","affiliation":[{"name":"Cardiology Clinic, Department of Cardiac, Thoracic, and Vascular Sciences and Public Health Padova, University of Padua, Italy (G.T., L.N.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pascal","family":"Le Prince","sequence":"additional","affiliation":[{"name":"La Piti\u00e9 Salp\u00e9tri\u00e8re, Paris, France (P.L.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olivier","family":"Darremont","sequence":"additional","affiliation":[{"name":"Clinique Saint-Augustin, Bordeaux, France (O.D.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Urena","sequence":"additional","affiliation":[{"name":"Bichat Hospital Paris, France (M.U.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio L.","family":"Bartorelli","sequence":"additional","affiliation":[{"name":"Centro Cardiologico Monzino IRCCS, University of Milan, Italy (A.L.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Flavien","family":"Vincent","sequence":"additional","affiliation":[{"name":"CHRU Lille, France (F.V.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomas","family":"Hovorka","sequence":"additional","affiliation":[{"name":"Edwards Lifesciences, Prague, Czech Republic (T.H., Y.A.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasmina","family":"Alcal\u00e1 Navarro","sequence":"additional","affiliation":[{"name":"Edwards Lifesciences, Prague, Czech Republic (T.H., Y.A.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Dumonteil","sequence":"additional","affiliation":[{"name":"Groupe CardioVasculaire Interventionnel (GCVI), Clinique Pasteur, Toulouse, France (N.D.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Ohlmann","sequence":"additional","affiliation":[{"name":"Department of Interventional Cardiology, University Hospital of Strasbourg, France (P.O.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olaf","family":"Wendler","sequence":"additional","affiliation":[{"name":"King\u2019s College Hospital, London, United Kingdom (O.W.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the SOURCE 3 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