{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T06:31:55Z","timestamp":1790145115047,"version":"4.0.1"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Interventions"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Despite the rapid adoption of transcatheter aortic valve replacement (TAVR) since its initial approval in 2011, the frequency and outcomes of surgical explantation of TAVR devices (TAVR-explant) is poorly understood.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>Patients undergoing TAVR-explant between January 2012 and June 2020 at 33 hospitals in Michigan were identified in the Society of Thoracic Surgeons Database and linked to index TAVR data from the Transcatheter Valve Therapy Registry through a statewide quality collaborative. The primary outcome was operative mortality. Indications for TAVR-explant, contraindications to redo TAVR, operative data, and outcomes were collected from Society of Thoracic Surgeons and Transcatheter Valve Therapy databases. Baseline Society of Thoracic Surgeons Predicted Risk of Mortality was compared between index TAVR and TAVR-explant.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>\n              Twenty-four surgeons at 12 hospitals performed TAVR-explants in 46 patients (median age, 73). The frequency of TAVR-explant was 0.4%, and the number of explants increased annually. Median time to TAVR-explant was 139 days and among known device types explanted, most were self-expanding valves (29\/41, 71%). Common indications for TAVR-explant were procedure-related failure (35%), paravalvular leak (28%), and need for other cardiac surgery (26%). Contraindications to redo TAVR included need for other cardiac surgery (28%), unsuitable noncoronary anatomy (13%), coronary obstruction (11%), and endocarditis (11%). Overall, 65% (30\/46) of patients underwent concomitant procedures, including aortic repair\/replacement in 33% (n=15), mitral surgery in 22% (n=10), and coronary artery bypass grafting in 16% (n=7). The median Society of Thoracic Surgeons Predicted Risk of Mortality was 4.2% at index TAVR and 9.3% at TAVR-explant (\n              <jats:italic>P<\/jats:italic>\n              =0.001). Operative mortality was 20% (9\/46) and 76% (35\/46) of patients had in-hospital complications. Of patients alive at discharge, 37% (17\/37) were discharged home and overall 3-month survival was 73\u00b114%.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>TAVR-explant is rare but increasing, and its clinical impact is substantial. As the utilization of TAVR expands into younger and lower-risk patients, providers should consider the potential for future TAVR-explant during selection of an initial valve strategy.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circinterventions.120.009927","type":"journal-article","created":{"date-parts":[[2021,3,15]],"date-time":"2021-03-15T10:00:49Z","timestamp":1615802449000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":46,"title":["Surgical Explantation of Transcatheter Aortic Valve Bioprostheses"],"prefix":"10.1161","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6988-7987","authenticated-orcid":true,"given":"Alexander A.","family":"Brescia","sequence":"first","affiliation":[{"name":"Department of Cardiac Surgery (A.A.B., G.M.D., S.F.), University of Michigan, Ann Arbor."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G. Michael","family":"Deeb","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery (A.A.B., G.M.D., S.F.), University of Michigan, Ann Arbor."},{"name":"Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor (G.M.D., S.L.W.S., D.T., C.H., P.F.T., M.C., F.L.S., S.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephane Leung Wai","family":"Sang","sequence":"additional","affiliation":[{"name":"Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor (G.M.D., S.L.W.S., D.T., C.H., P.F.T., M.C., F.L.S., S.F.)."},{"name":"Spectrum Health Medical Group, Cardiothoracic Surgery, Grand Rapids, MI (S.L.W.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daizo","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor (G.M.D., S.L.W.S., D.T., C.H., P.F.T., M.C., F.L.S., S.F.)."},{"name":"Henry Ford Hospital Division of Cardiac Surgery, Detroit, MI (D.T.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. Michael","family":"Grossman","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine (P.M.G., D.S., S.J.C.), University of Michigan, Ann Arbor."},{"name":"Blue Cross Blue Shield Cardiovascular Consortium, Ann Arbor, MI (P.M.G., D.S., S.J.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devraj","family":"Sukul","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine (P.M.G., D.S., S.J.C.), University of Michigan, Ann Arbor."},{"name":"Blue Cross Blue Shield Cardiovascular Consortium, Ann Arbor, MI (P.M.G., D.S., S.J.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang","family":"He","sequence":"additional","affiliation":[{"name":"Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor (G.M.D., S.L.W.S., D.T., C.H., P.F.T., M.C., F.L.S., S.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1567-7327","authenticated-orcid":true,"given":"Patricia F.","family":"Theurer","sequence":"additional","affiliation":[{"name":"Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor (G.M.D., S.L.W.S., D.T., C.H., P.F.T., M.C., F.L.S., S.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melissa","family":"Clark","sequence":"additional","affiliation":[{"name":"Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor (G.M.D., S.L.W.S., D.T., C.H., P.F.T., M.C., F.L.S., S.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis L.","family":"Shannon","sequence":"additional","affiliation":[{"name":"Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor (G.M.D., S.L.W.S., D.T., C.H., P.F.T., M.C., F.L.S., S.F.)."},{"name":"Division of Cardiovascular Surgery, Beaumont Health, Royal Oak, MI (F.L.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanley J.","family":"Chetcuti","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine (P.M.G., D.S., S.J.C.), University of Michigan, Ann Arbor."},{"name":"Blue Cross Blue Shield Cardiovascular Consortium, Ann Arbor, MI (P.M.G., D.S., S.J.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7898-5159","authenticated-orcid":true,"given":"Shinichi","family":"Fukuhara","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery (A.A.B., G.M.D., S.F.), University of Michigan, Ann Arbor."},{"name":"Michigan Society of Thoracic and Cardiovascular Surgeons Quality Collaborative, Ann Arbor (G.M.D., S.L.W.S., D.T., C.H., P.F.T., M.C., F.L.S., S.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the Michigan Society of Thoracic and Cardiovascular Surgeons and the Blue Cross Blue Shield of Michigan Cardiovascular 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Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCINTERVENTIONS.120.009927","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T02:26:37Z","timestamp":1715567197000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCINTERVENTIONS.120.009927"}},"subtitle":["A Statewide Experience"],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":14,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4]]}},"alternative-id":["10.1161\/CIRCINTERVENTIONS.120.009927"],"URL":"https:\/\/doi.org\/10.1161\/circinterventions.120.009927","relation":{},"ISSN":["1941-7640","1941-7632"],"issn-type":[{"value":"1941-7640","type":"print"},{"value":"1941-7632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"2020-07-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-01-12","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-03-15","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e009927"}}