{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T11:13:18Z","timestamp":1788174798009,"version":"build-2803163510"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","license":[{"start":{"date-parts":[[2023,6,1]],"date-time":"2023-06-01T00:00:00Z","timestamp":1685577600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005971","name":"Deutsche Herzstiftung","doi-asserted-by":"crossref","award":["S\/04\/21"],"award-info":[{"award-number":["S\/04\/21"]}],"id":[{"id":"10.13039\/501100005971","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100001316","name":"Abbott Laboratories","doi-asserted-by":"crossref","award":["N\/A"],"award-info":[{"award-number":["N\/A"]}],"id":[{"id":"10.13039\/100001316","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Interventions"],"published-print":{"date-parts":[[2023,6]]},"abstract":"<jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Transcatheter mitral valve replacement (TMVR) is an emerging therapeutic alternative for patients with secondary mitral regurgitation (MR). Outcomes of TMVR versus guideline-directed medical therapy (GDMT) have not been investigated for this population. This study aimed to compare clinical outcomes of patients with secondary MR undergoing TMVR versus GDMT alone.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>The CHOICE-MI registry (Choice of Optimal Transcatheter Treatment for Mitral Insufficiency) included patients with MR undergoing TMVR using dedicated devices. Patients with MR pathogeneses other than secondary MR were excluded. Patients treated with GDMT alone were derived from the control arm of the COAPT trial (Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation). We compared outcomes between the TMVR and GDMT groups, using propensity score matching to adjust for baseline differences.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>\n              After propensity score matching, 97 patient pairs undergoing TMVR (72.9\u00b18.7 years; 60.8% men; transapical access, 91.8%) versus GDMT (73.1\u00b111.0 years; 59.8% men) were compared. At 1 and 2 years, residual MR was \u22641+ in all patients of the TMVR group compared with 6.9% and 7.7%, respectively, in those receiving GDMT alone (both\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001). The 2-year rate of heart failure hospitalization was significantly lower in the TMVR group (32.8% versus 54.4%; hazard ratio, 0.59 [95% CI, 0.35\u20130.99];\n              <jats:italic>P<\/jats:italic>\n              =0.04). Among survivors, a higher proportion of patients were in the New York Heart Association functional class I or II in the TMVR group at 1 year (78.2% versus 59.7%;\n              <jats:italic>P<\/jats:italic>\n              =0.03) and at 2 years (77.8% versus 53.2%;\n              <jats:italic>P<\/jats:italic>\n              =0.09). Two-year mortality was similar in the 2 groups (TMVR versus GDMT, 36.8% versus 40.8%; hazard ratio, 1.01 [95% CI, 0.62\u20131.64];\n              <jats:italic>P<\/jats:italic>\n              =0.98).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>In this observational comparison, over 2-year follow-up, TMVR using mostly transapical devices in patients with secondary MR was associated with significant reduction of MR, symptomatic improvement, less frequent hospitalizations for heart failure, and similar mortality compared with GDMT.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Registration:<\/jats:title>\n            <jats:p>\n              URL:\n              <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/clinicaltrials.gov\">https:\/\/clinicaltrials.gov<\/jats:ext-link>\n              ; Unique identifier: NCT04688190 (CHOICE-MI) and NCT01626079 (COAPT).\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circinterventions.123.013045","type":"journal-article","created":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T06:30:11Z","timestamp":1684305011000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":20,"title":["Transcatheter Mitral Valve Replacement Versus Medical Therapy for Secondary Mitral Regurgitation: A Propensity Score\u2013Matched Comparison"],"prefix":"10.1161","volume":"16","clinical-trial-number":[{"clinical-trial-number":"nct01626079","registry":"10.18810\/clinical-trials-gov"},{"clinical-trial-number":"nct04688190","registry":"10.18810\/clinical-trials-gov"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5752-4951","authenticated-orcid":true,"given":"Sebastian","family":"Ludwig","sequence":"first","affiliation":[{"name":"Departments of Cardiology (S.L.), University Heart and Vascular Center Hamburg, Germany."},{"name":"German Center for Cardiovascular Research, Partner site Hamburg\/Kiel\/L\u00fcbeck, Germany (S.L.)."},{"name":"Cardiovascular Research Foundation, New York City, NY (S.L., D.J.C., A.C., A.S., Z.Z., Y.L., B.R., J.F.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2237-9050","authenticated-orcid":true,"given":"Lenard","family":"Conradi","sequence":"additional","affiliation":[{"name":"Cardiovascular Surgery (L.C.), University Heart and Vascular Center Hamburg, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9163-724X","authenticated-orcid":true,"given":"David J.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Foundation, New York City, NY (S.L., D.J.C., A.C., A.S., Z.Z., Y.L., B.R., J.F.G.)."},{"name":"St. Francis Hospital, Roslyn, New York (D.J.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1662-7874","authenticated-orcid":true,"given":"Augustin","family":"Coisne","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Foundation, New York City, NY (S.L., D.J.C., A.C., A.S., Z.Z., Y.L., B.R., J.F.G.)."},{"name":"University Lille, Inserm, CHU Lille, Institut Pasteur de Lille, France (A.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4731-4384","authenticated-orcid":true,"given":"Andrea","family":"Scotti","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Foundation, New York City, NY (S.L., D.J.C., A.C., A.S., Z.Z., Y.L., B.R., J.F.G.)."},{"name":"Montefiore-Einstein Center for Heart and Vascular Care, Montefiore Medical Center, NY (A.S., A.L.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4805-1037","authenticated-orcid":true,"given":"William T.","family":"Abraham","sequence":"additional","affiliation":[{"name":"Departments of Medicine, Physiology, and Cell Biology, Division of Cardiovascular Medicine, Davis Heart and Lung Research Institute, The Ohio State University, Columbus (W.T.A.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Walid","family":"Ben Ali","sequence":"additional","affiliation":[{"name":"Structural Valve Program, Montreal Heart Institute, Canada (W.B.A.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhipeng","family":"Zhou","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Foundation, New York City, NY (S.L., D.J.C., A.C., A.S., Z.Z., Y.L., B.R., J.F.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8440-9337","authenticated-orcid":true,"given":"Yanru","family":"Li","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Foundation, New York City, NY (S.L., D.J.C., A.C., A.S., Z.Z., Y.L., B.R., J.F.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1547-4869","authenticated-orcid":true,"given":"Saibal","family":"Kar","sequence":"additional","affiliation":[{"name":"Los Robles Regional Medical Center, Thousand Oaks, CA (S.K.)."},{"name":"Bakersfield Heart Hospital, CA (S.K.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2248-9252","authenticated-orcid":true,"given":"Alison","family":"Duncan","sequence":"additional","affiliation":[{"name":"Royal Brompton Hospital, London, United Kingdom (A.D.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. Scott","family":"Lim","sequence":"additional","affiliation":[{"name":"Division of Cardiology, University of Virginia, Charlottesville (D.S.L.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3855-1815","authenticated-orcid":true,"given":"Marianna","family":"Adamo","sequence":"additional","affiliation":[{"name":"Cardiac Catheterization Laboratory and Cardiology, ASST Spedali Civili and Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Italy (M. Adamo, M.M.)."},{"name":"Department of Cardiology, Heart Center, University of Cologne, Germany (M. Adam)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4155-4451","authenticated-orcid":true,"given":"Bj\u00f6rn","family":"Redfors","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Foundation, New York City, NY (S.L., D.J.C., A.C., A.S., Z.Z., Y.L., B.R., J.F.G.)."},{"name":"NewYork-Presbyterian Hospital\/Columbia University Medical Center (B.R.)."},{"name":"Department of Cardiology, Sahlgrenska University Hospital, Gothenburg, Sweden (B.R.)."},{"name":"Wallenberg Laboratory, Institute of Medicine, University of Gothenburg, Sweden (B.R.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5281-0166","authenticated-orcid":true,"given":"David W.M.","family":"Muller","sequence":"additional","affiliation":[{"name":"Cardiology Department, St. Vincent\u2019s Hospital, Sydney, Australia (D.W.M.M.)."},{"name":"School of Clinical Medicine, UNSW Medicine and Health UNSW Sydney, Australia (D.W.M.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John G.","family":"Webb","sequence":"additional","affiliation":[{"name":"St. Paul\u2019s Hospital, Vancouver, British Columbia, Canada (J.G.W.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anna S.","family":"Petronio","sequence":"additional","affiliation":[{"name":"Cardiac Catheterization Laboratory, Cardiothoracic and Vascular Department, University of Pisa, Italy (A.S.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6886-3660","authenticated-orcid":true,"given":"Hendrik","family":"Ruge","sequence":"additional","affiliation":[{"name":"Departments of Cardiovascular Surgery (H.R.), German Heart Center Munich, Germany."},{"name":"Cardiovascular Surgery, INSURE\u2013Institute for Translational Cardiac Surgery (H.R.), German Heart Center Munich, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georg","family":"Nickenig","sequence":"additional","affiliation":[{"name":"Heart Center Bonn, Germany (G.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Sondergaard","sequence":"additional","affiliation":[{"name":"Rigshospitalet, Copenhagen, Denmark (L.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6990-8135","authenticated-orcid":true,"given":"Matti","family":"Adam","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Heart Center, University of Cologne, Germany (M. Adam)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damiano","family":"Regazzoli","sequence":"additional","affiliation":[{"name":"IRCCS Humanitas Research Hospital, Milan, Italy (D.R.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6744-1850","authenticated-orcid":true,"given":"Andrea","family":"Garatti","sequence":"additional","affiliation":[{"name":"IRCCS Policlinico San Donato, Milan, Italy (A.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tobias","family":"Schmidt","sequence":"additional","affiliation":[{"name":"Medical Clinic II, University Heart Center L\u00fcbeck, Germany (T.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4950-5432","authenticated-orcid":true,"given":"Martin","family":"Andreas","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Medical University of Vienna, Austria (M. Andreas)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6381-6766","authenticated-orcid":true,"given":"Gry","family":"Dahle","sequence":"additional","affiliation":[{"name":"Oslo University Hospital, Rikshospitalet, Norway (G.D.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2892-8949","authenticated-orcid":true,"given":"Thomas","family":"Walther","sequence":"additional","affiliation":[{"name":"Frankfurt University Hospital, Germany (T.W.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joerg","family":"Kempfert","sequence":"additional","affiliation":[{"name":"German Heart Institute Berlin, Germany (J.K.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7219-990X","authenticated-orcid":true,"given":"Gilbert H.L.","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Mount Sinai Health System, New York, NY (G.H.L.T.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1937-063X","authenticated-orcid":true,"given":"Simon","family":"Redwood","sequence":"additional","affiliation":[{"name":"St. Thomas\u2019 Hospital, London, United Kingdom (S.R.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurizio","family":"Taramasso","sequence":"additional","affiliation":[{"name":"HerzZentrum Hirslanden Z\u00fcrich, Switzerland (M.T.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5416-165X","authenticated-orcid":true,"given":"Fabien","family":"Praz","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinik fu\u0308r Kardiologie, Inselspital Bern, Switzerland (F.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neil","family":"Fam","sequence":"additional","affiliation":[{"name":"St. Michael\u2019s Hospital, University of Toronto, Canada (N.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Dumonteil","sequence":"additional","affiliation":[{"name":"Groupe CardioVasculaire Interventionnel, Clinique Pasteur Toulouse, France (N.D.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1644-9542","authenticated-orcid":true,"given":"Jean-Fran\u00e7ois","family":"Obadia","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Louis Pradel Cardiologic Hospital, Lyon, France (J.-F.O.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1356-0037","authenticated-orcid":true,"given":"Ralph Stephan","family":"von Bardeleben","sequence":"additional","affiliation":[{"name":"Heart Valve Center and Heart and Vascular Center, Universit\u00e4tsmedizin Mainz, Germany (R.S.v.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8839-7476","authenticated-orcid":true,"given":"Tanja K.","family":"Rudolph","sequence":"additional","affiliation":[{"name":"Department of Interventional and General Cardiology, Heart and Diabetes Center North Rhine-Westphalia, Bad Oeynhausen, Ruhr University Bochum, Germany (T.K.R.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2880-6132","authenticated-orcid":true,"given":"Michael J.","family":"Reardon","sequence":"additional","affiliation":[{"name":"Houston Methodist Hospital, TX (M.J.R.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4846-8529","authenticated-orcid":true,"given":"Marco","family":"Metra","sequence":"additional","affiliation":[{"name":"Cardiac Catheterization Laboratory and Cardiology, ASST Spedali Civili and Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, Italy (M. Adamo, M.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3075-0203","authenticated-orcid":true,"given":"Paolo","family":"Denti","sequence":"additional","affiliation":[{"name":"Ospedale San Raffaele, Milan, Italy (P.D.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3148-9158","authenticated-orcid":true,"given":"Michael J.","family":"Mack","sequence":"additional","affiliation":[{"name":"Baylor Scott and White Heart Hospital Plano, TX (M.J.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2909-7961","authenticated-orcid":true,"given":"J\u00f6rg","family":"Hausleiter","sequence":"additional","affiliation":[{"name":"Medizinische Klinik und Poliklinik I, Klinikum der Universit\u00e4t Mu\u0308nchen, Munich, Germany (J.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1744-5271","authenticated-orcid":true,"given":"Federico M.","family":"Asch","sequence":"additional","affiliation":[{"name":"Cardiovascular Core Laboratories, MedStar Health Research Institute, Washington, DC (F.M.A.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9035-343X","authenticated-orcid":true,"given":"Azeem","family":"Latib","sequence":"additional","affiliation":[{"name":"Montefiore-Einstein Center for Heart and Vascular Care, Montefiore Medical Center, NY (A.S., A.L.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"JoAnn","family":"Lindenfeld","sequence":"additional","affiliation":[{"name":"Advanced Heart Failure and Cardiac Transplantation Section, Vanderbilt Heart and Vascular Institute, Nashville, TN (J.L.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4169-3766","authenticated-orcid":true,"given":"Thomas","family":"Modine","sequence":"additional","affiliation":[{"name":"Centre Hospitalier Universitaire de Bordeaux, France (T.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3416-8210","authenticated-orcid":true,"given":"Gregg W.","family":"Stone","sequence":"additional","affiliation":[{"name":"The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, NY (G.W.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2399-8320","authenticated-orcid":true,"given":"Juan F.","family":"Granada","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Foundation, New York City, NY (S.L., D.J.C., A.C., A.S., Z.Z., Y.L., B.R., J.F.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"on behalf of the CHOICE-MI and the COAPT Trial Investigators","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2017.2976"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.02.009"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1806640"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2020.12.047"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2016.10.068"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2021.08.060"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.10.061"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.2492"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezu546"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.06.1208"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2020.08.006"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2021.10.018"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1805374"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2019.09.017"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1080\/24748706.2021.1902595"},{"key":"e_1_3_3_17_2","unstructured":"Rogers J. Contemporary clinical and echocardiographic outcomes of 1000+ patients treated with MitraClipTM G4: results from the EXPAND G4 post approval study. Oral presentation at: Transcatheter Cardiovascular Therpeutics (TCT); September 2022; Boston MA."},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2021.10.011"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.2797"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.shj.2022.100025"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2021.04.051"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2020.12.038"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.012525"}],"container-title":["Circulation: Cardiovascular Interventions"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCINTERVENTIONS.123.013045","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T02:31:19Z","timestamp":1715567479000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCINTERVENTIONS.123.013045"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6]]},"references-count":22,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6]]}},"alternative-id":["10.1161\/CIRCINTERVENTIONS.123.013045"],"URL":"https:\/\/doi.org\/10.1161\/circinterventions.123.013045","relation":{},"ISSN":["1941-7640","1941-7632"],"issn-type":[{"value":"1941-7640","type":"print"},{"value":"1941-7632","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,6]]},"assertion":[{"value":"2023-03-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-09","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-05-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}