{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T08:07:21Z","timestamp":1784966841139,"version":"3.55.0"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Interventions"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:sec>\n            <jats:title>BACKGROUND:<\/jats:title>\n            <jats:p>SAPIEN3 (S3) is a ubiquitous redo\u2013transcatheter aortic valve (TAV) replacement alternative for degenerated Evolut valves, but S3 sizing for S3-in-Evolut remains unclear. We sought to compare the impact of in vivo computed tomography (CT)-sizing on redo-TAV feasibility for S3-in-Evolut with traditional bench-sizing.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>METHODS:<\/jats:title>\n            <jats:p>CT scans of 290 patients treated using Evolut R\/PRO\/PRO+ between July 2015 and December 2021 were analyzed. S3-in-Evolut was simulated using S3 outflow\/neoskirt plane (NSP) at node-6, -5, and -4. CT-sizing for S3 was determined by averaging 4 areas of the Evolut stent frame at NSP level and 3 nodes below. Redo-TAV was deemed feasible if the NSP was below the coronaries, or the narrowest valve (virtual S3)-to-aorta distance was &gt;4 mm. Risk of prosthesis-patient mismatch was estimated using predicted indexed-effective orifice area.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>RESULTS:<\/jats:title>\n            <jats:p>\n              Compared with bench-sizing, CT-sizing yielded smaller S3 size in 82% at node-6, 81% at node-5, and 84% at node-4. Factors associated with CT-sizing less than bench-sizing were larger index Evolut size, underexpansion of index Evolut, and shallower implant depth (all\n              <jats:italic toggle=\"yes\">P<\/jats:italic>\n              &lt;0.05). CT-sizing increased redo-TAV feasibility by +8% at node-6, +10% at node-5, and +4% at node-4. Redo-TAV feasibility increased with annulus size, sinotubular junction dimensions, coronary heights, index Evolut size, deeper Evolut implant depth, and lower NSP levels (all\n              <jats:italic toggle=\"yes\">P<\/jats:italic>\n              &lt;0.05). CT-sizing had a slightly higher estimated risk of severe prosthesis-patient mismatch (9% at node-6, 7% at node-5, and 6% at node-4), which could be mitigated by changing the NSP.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>CONCLUSIONS:<\/jats:title>\n            <jats:p>CT-sizing for S3-in-Evolut is associated with higher feasibility of redo-TAV compared with bench-sizing, potentially reducing the risk of excessive oversizing and S3 underexpansion. Further validation using real-world clinical data is necessary.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circinterventions.123.013903","type":"journal-article","created":{"date-parts":[[2024,6,27]],"date-time":"2024-06-27T09:01:20Z","timestamp":1719478880000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["In Vivo Computed Tomography Sizing for Redo\u2013Transcatheter Aortic Valve Replacement in Evolut Valves: Impact on Sizing, Feasibility, and Prosthesis-Patient Mismatch"],"prefix":"10.1161","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0087-4168","authenticated-orcid":true,"given":"Atsushi","family":"Okada","sequence":"first","affiliation":[{"name":"Valve Science Center (A.O., K.R.T., E.W.-K., L.I.S., M.R.B., H.K., C.W., A.P., J.R.L., P.S., V.N.B.), Minneapolis Heart Institute Foundation, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7235-5551","authenticated-orcid":true,"given":"Miho","family":"Fukui","sequence":"additional","affiliation":[{"name":"Cardiovascular Imaging Research Center and Core Lab (M.F., J.L.C.), Minneapolis Heart Institute Foundation, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9426-3618","authenticated-orcid":true,"given":"Syed","family":"Zaid","sequence":"additional","affiliation":[{"name":"Michael E. DeBakey VA Medical Center, Baylor College of Medicine, Houston, TX (S.Z.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kiahltone R.","family":"Thao","sequence":"additional","affiliation":[{"name":"Valve Science Center (A.O., K.R.T., E.W.-K., L.I.S., M.R.B., H.K., C.W., A.P., J.R.L., P.S., V.N.B.), Minneapolis Heart Institute Foundation, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0142-1248","authenticated-orcid":true,"given":"Evan","family":"Walser-Kuntz","sequence":"additional","affiliation":[{"name":"Valve Science Center (A.O., K.R.T., E.W.-K., L.I.S., M.R.B., H.K., C.W., A.P., J.R.L., P.S., V.N.B.), Minneapolis Heart Institute Foundation, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2388-0640","authenticated-orcid":true,"given":"Larissa I.","family":"Stanberry","sequence":"additional","affiliation":[{"name":"Valve Science Center (A.O., K.R.T., E.W.-K., L.I.S., M.R.B., H.K., C.W., A.P., J.R.L., P.S., V.N.B.), Minneapolis Heart Institute Foundation, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0217-1834","authenticated-orcid":true,"given":"Marcus R.","family":"Burns","sequence":"additional","affiliation":[{"name":"Valve Science Center (A.O., K.R.T., E.W.-K., L.I.S., M.R.B., H.K., C.W., A.P., J.R.L., P.S., V.N.B.), Minneapolis Heart Institute Foundation, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Koike","sequence":"additional","affiliation":[{"name":"Valve Science Center (A.O., K.R.T., E.W.-K., L.I.S., M.R.B., H.K., C.W., A.P., J.R.L., P.S., V.N.B.), Minneapolis Heart Institute Foundation, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Wang","sequence":"additional","affiliation":[{"name":"Valve Science Center (A.O., K.R.T., E.W.-K., L.I.S., M.R.B., H.K., C.W., A.P., J.R.L., P.S., V.N.B.), Minneapolis Heart Institute Foundation, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asa","family":"Phichaphop","sequence":"additional","affiliation":[{"name":"Valve Science Center (A.O., K.R.T., E.W.-K., L.I.S., M.R.B., H.K., C.W., A.P., J.R.L., P.S., V.N.B.), Minneapolis Heart Institute Foundation, MN."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John R.","family":"Lesser","sequence":"additional","affiliation":[{"name":"Valve Science Center (A.O., K.R.T., E.W.-K., L.I.S., M.R.B., H.K., C.W., A.P., J.R.L., P.S., V.N.B.), Minneapolis Heart Institute Foundation, MN."},{"name":"Minneapolis Heart Institute at Abbott Northwestern Hospital, MN (J.R.L., J.L.C., P.S., V.N.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u00e3o L.","family":"Cavalcante","sequence":"additional","affiliation":[{"name":"Cardiovascular Imaging Research Center and Core Lab (M.F., J.L.C.), Minneapolis Heart Institute Foundation, MN."},{"name":"Minneapolis Heart Institute at Abbott Northwestern Hospital, MN (J.R.L., J.L.C., P.S., V.N.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6401-854X","authenticated-orcid":true,"given":"Paul","family":"Sorajja","sequence":"additional","affiliation":[{"name":"Valve Science Center (A.O., K.R.T., E.W.-K., L.I.S., M.R.B., H.K., C.W., A.P., J.R.L., P.S., V.N.B.), Minneapolis Heart Institute Foundation, MN."},{"name":"Minneapolis Heart Institute at Abbott Northwestern Hospital, MN (J.R.L., J.L.C., P.S., V.N.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2579-6434","authenticated-orcid":true,"given":"Vinayak N.","family":"Bapat","sequence":"additional","affiliation":[{"name":"Valve Science Center (A.O., K.R.T., E.W.-K., L.I.S., M.R.B., H.K., C.W., A.P., J.R.L., P.S., V.N.B.), Minneapolis Heart Institute Foundation, MN."},{"name":"Minneapolis Heart Institute at Abbott Northwestern Hospital, MN (J.R.L., 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