{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T22:53:06Z","timestamp":1778799186405,"version":"3.51.4"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Quality and Outcomes"],"published-print":{"date-parts":[[2009,11]]},"abstract":"<jats:p>\n            <jats:bold>\n              <jats:italic>Background\u2014<\/jats:italic>\n            <\/jats:bold>\n            Percutaneous coronary intervention (PCI) has witnessed rapid technological advancements, resulting in improved safety and effectiveness over time. Little, however, is known about the temporal impact on patient-reported symptoms and quality of life after PCI.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Methods and Results\u2014<\/jats:italic>\n            <\/jats:bold>\n            Temporal trends in post-PCI symptoms were analyzed using 8879 consecutive patients enrolled in the National Heart, Lung, and Blood Institute\u2013sponsored Dynamic Registry (wave 1: 1997 [bare metal stents], wave 2: 1999 [uniform use of stents], wave 3: 2001 [brachytherapy], wave 4, 5: 2004, 2006 [drug eluting stents]). Patients undergoing PCI in the recent waves were older and more often reported comorbidities. However, fewer patients across the waves reported post-PCI angina at one year (wave 1 to 5: 24%, 23%, 18%, 20%, 20%;\n            <jats:italic>P<\/jats:italic>\n            <jats:sub>trend<\/jats:sub>\n            &lt;0.001). The lower risk of angina in recent waves was explained by patient characteristics including use of antianginal medications at discharge (relative risk [95% CI] for waves 2, 3, 4 versus 1: 1.0 [0.9 to 1.2], 0.9 [0.7 to 1.1], 1.0 [0.8 to 1.3], 0.9 [0.7 to 1.1]). Similar trend was seen in the average quality of life scores over time (adjusted mean score for waves 1 to 5: 6.2, 6.5, 6.6 and 6.6;\n            <jats:italic>P<\/jats:italic>\n            <jats:sub>trend<\/jats:sub>\n            =0.01). Other factors associated with angina at 1 year included younger age, female gender, prior revascularization, need for repeat PCI, and hospitalization for myocardial infarction over 1 year.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Conclusion\u2014<\/jats:italic>\n            <\/jats:bold>\n            Favorable temporal trends are seen in patient-reported symptoms after PCI in routine clinical practice. Specific subgroups, however, remain at risk for symptoms at 1 year and thus warrant closer attention.\n          <\/jats:p>","DOI":"10.1161\/circoutcomes.109.869131","type":"journal-article","created":{"date-parts":[[2009,10,14]],"date-time":"2009-10-14T06:56:30Z","timestamp":1255503390000},"page":"607-615","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":41,"title":["Temporal Trends in Patient-Reported Angina at 1 Year After Percutaneous Coronary Revascularization in the Stent Era"],"prefix":"10.1161","volume":"2","author":[{"given":"Lakshmi","family":"Venkitachalam","sequence":"first","affiliation":[{"name":"From the Cardiovascular Institute, Department of Medicine, School of Medicine (L.V., S.R.M., O.C.M.), and the Department of Epidemiology (F.S., K.S.-T., C.H.B., S.F.K.), Graduate School of Public Health, University of Pittsburgh, Pa; the College of Nursing (K.E.K.), University of South Florida, Tampa, Fla; the University of New Mexico School of Medicine (W.L.), Albuquerque, NM; the Department of Cardiology (J.S.), New York University Medical Center, New York, NY; Lenox Hill Hospital (H.A.C.), New..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin E.","family":"Kip","sequence":"additional","affiliation":[{"name":"From the Cardiovascular Institute, Department of Medicine, School of Medicine (L.V., S.R.M., O.C.M.), and the Department of Epidemiology (F.S., K.S.-T., C.H.B., S.F.K.), Graduate School of Public Health, University of Pittsburgh, Pa; the College of Nursing (K.E.K.), University of South Florida, Tampa, Fla; the University of New Mexico School of Medicine (W.L.), Albuquerque, NM; the Department of Cardiology (J.S.), New York University Medical Center, New York, NY; Lenox Hill Hospital (H.A.C.), New..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suresh R.","family":"Mulukutla","sequence":"additional","affiliation":[{"name":"From the Cardiovascular Institute, Department of Medicine, School of Medicine (L.V., S.R.M., O.C.M.), and the Department of Epidemiology (F.S., K.S.-T., C.H.B., S.F.K.), Graduate School of Public Health, University of Pittsburgh, Pa; the College of Nursing (K.E.K.), University of South Florida, Tampa, Fla; the University of New Mexico School of Medicine (W.L.), Albuquerque, NM; the Department of Cardiology (J.S.), New York University Medical Center, New York, NY; Lenox Hill Hospital (H.A.C.), New..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faith","family":"Selzer","sequence":"additional","affiliation":[{"name":"From the Cardiovascular Institute, Department of Medicine, School of Medicine (L.V., S.R.M., O.C.M.), and the Department of Epidemiology (F.S., K.S.-T., C.H.B., S.F.K.), Graduate School of Public Health, University of Pittsburgh, Pa; the College of Nursing (K.E.K.), University of South Florida, Tampa, Fla; the University of New Mexico School of Medicine (W.L.), Albuquerque, NM; the Department of Cardiology (J.S.), New York University Medical Center, New York, NY; Lenox Hill Hospital (H.A.C.), New..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Warren","family":"Laskey","sequence":"additional","affiliation":[{"name":"From the Cardiovascular Institute, Department of Medicine, School of Medicine (L.V., S.R.M., O.C.M.), and the Department of Epidemiology (F.S., K.S.-T., C.H.B., S.F.K.), Graduate School of Public Health, University of Pittsburgh, Pa; the College of Nursing (K.E.K.), University of South Florida, Tampa, Fla; the University of New Mexico School of Medicine (W.L.), Albuquerque, NM; the Department of Cardiology (J.S.), New York University Medical Center, New York, NY; Lenox Hill Hospital (H.A.C.), New..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Slater","sequence":"additional","affiliation":[{"name":"From the Cardiovascular Institute, Department of Medicine, School of Medicine (L.V., S.R.M., O.C.M.), and the Department of Epidemiology (F.S., K.S.-T., C.H.B., S.F.K.), Graduate School of Public Health, University of Pittsburgh, Pa; the College of Nursing (K.E.K.), University of South Florida, Tampa, Fla; the University of New Mexico School of Medicine (W.L.), Albuquerque, NM; the Department of Cardiology (J.S.), New York University Medical Center, New York, NY; Lenox Hill Hospital (H.A.C.), New..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Howard A.","family":"Cohen","sequence":"additional","affiliation":[{"name":"From the Cardiovascular Institute, Department of Medicine, School of Medicine (L.V., S.R.M., O.C.M.), and the Department of Epidemiology (F.S., K.S.-T., C.H.B., S.F.K.), Graduate School of Public Health, University of Pittsburgh, Pa; the College of Nursing (K.E.K.), University of South Florida, Tampa, Fla; the University of New Mexico School of Medicine (W.L.), Albuquerque, NM; the Department of Cardiology (J.S.), New York University Medical Center, New York, NY; Lenox Hill Hospital (H.A.C.), New..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert L.","family":"Wilensky","sequence":"additional","affiliation":[{"name":"From the Cardiovascular Institute, Department of Medicine, School of Medicine (L.V., S.R.M., O.C.M.), and the Department of Epidemiology (F.S., K.S.-T., C.H.B., S.F.K.), Graduate School of Public Health, University of Pittsburgh, Pa; the College of Nursing (K.E.K.), University of South Florida, Tampa, Fla; the University of New Mexico School of Medicine (W.L.), Albuquerque, NM; the Department of Cardiology (J.S.), New York University Medical Center, New York, NY; Lenox Hill Hospital (H.A.C.), New..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David O.","family":"Williams","sequence":"additional","affiliation":[{"name":"From the Cardiovascular Institute, Department of Medicine, School of Medicine (L.V., S.R.M., O.C.M.), and the Department of Epidemiology (F.S., K.S.-T., C.H.B., S.F.K.), Graduate School of Public Health, University of Pittsburgh, Pa; the College of Nursing (K.E.K.), University of South Florida, Tampa, Fla; the University of New Mexico School of Medicine (W.L.), Albuquerque, NM; the Department of Cardiology (J.S.), New York University Medical Center, New York, NY; Lenox Hill Hospital (H.A.C.), New..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oscar C.","family":"Marroquin","sequence":"additional","affiliation":[{"name":"From the Cardiovascular Institute, Department of Medicine, School of Medicine (L.V., S.R.M., O.C.M.), and the Department of Epidemiology (F.S., K.S.-T., C.H.B., S.F.K.), Graduate School of Public Health, University of Pittsburgh, Pa; the College of Nursing (K.E.K.), University of South Florida, Tampa, Fla; the University of New Mexico School of Medicine (W.L.), Albuquerque, NM; the Department of Cardiology (J.S.), New York University Medical Center, New York, NY; Lenox Hill Hospital (H.A.C.), New..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kim","family":"Sutton-Tyrrell","sequence":"additional","affiliation":[{"name":"From the Cardiovascular Institute, Department of Medicine, School of Medicine (L.V., S.R.M., O.C.M.), and the Department of Epidemiology (F.S., K.S.-T., C.H.B., S.F.K.), Graduate School of Public Health, University of Pittsburgh, Pa; the College of Nursing (K.E.K.), University of South Florida, Tampa, Fla; the University of New Mexico School of Medicine (W.L.), Albuquerque, NM; the Department of Cardiology (J.S.), New York University Medical Center, New York, NY; Lenox Hill Hospital (H.A.C.), New..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clareann H.","family":"Bunker","sequence":"additional","affiliation":[{"name":"From the Cardiovascular Institute, Department of Medicine, School of Medicine (L.V., S.R.M., O.C.M.), and the Department of Epidemiology (F.S., K.S.-T., C.H.B., S.F.K.), Graduate School of Public Health, University of Pittsburgh, Pa; the College of Nursing (K.E.K.), University of South Florida, Tampa, Fla; the University of New Mexico School of Medicine (W.L.), Albuquerque, NM; the Department of Cardiology (J.S.), New York University Medical Center, New York, NY; Lenox Hill Hospital (H.A.C.), New..."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheryl F.","family":"Kelsey","sequence":"additional","affiliation":[{"name":"From the Cardiovascular Institute, Department of Medicine, School of Medicine (L.V., S.R.M., O.C.M.), and the Department of Epidemiology (F.S., K.S.-T., C.H.B., S.F.K.), Graduate School of Public Health, University of Pittsburgh, Pa; the College of Nursing (K.E.K.), University of South Florida, Tampa, Fla; the University of New Mexico School of Medicine (W.L.), Albuquerque, NM; the Department of Cardiology (J.S.), New York University Medical Center, New York, NY; Lenox Hill Hospital (H.A.C.), New..."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.102.24.2945"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.108.825323"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000020688.24874.90"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199201023260102"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01599-6"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1067\/mhj.2002.125505"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.80.3.2527641"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199607253350401"},{"key":"e_1_3_2_9_2","first-page":"645","volume":"27","year":"1962","unstructured":"ROSE GA. 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