{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T15:06:18Z","timestamp":1787151978013,"version":"build-2736575974"},"reference-count":49,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Quality and Outcomes"],"published-print":{"date-parts":[[2010,3]]},"abstract":"<jats:p>\n            <jats:bold>\n              <jats:italic>Background\u2014<\/jats:italic>\n            <\/jats:bold>\n            Prior studies have associated low social support (SS) with increased rehospitalization and mortality after acute myocardial infarction. However, relatively little is known about whether similar patterns exist for other outcomes, such as health status and depressive symptoms, and whether these patterns vary by sex.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Methods and Results\u2014<\/jats:italic>\n            <\/jats:bold>\n            Using data from 2411 English- or Spanish-speaking patients with acute myocardial infarction enrolled in a 19-center prospective study, we examined the association of SS (low, moderate, high) with health status (angina, disease-specific quality of life, general physical and mental functioning) and depressive symptoms over the first year of recovery. Overall and sex-stratified associations were evaluated using mixed-effects Poisson and linear regression, adjusting for site, baseline health status, baseline depressive symptoms, and demographic and clinical factors. Patients with the lowest SS (relative to those with the highest) had increased risk of angina (relative risk, 1.27; 95% confidence interval [CI], 1.10, 1.48); lower disease-specific quality of life (mean difference [\u03b2]=\u22123.33; 95% CI, \u22125.25, \u22121.41), lower mental functioning (\u03b2=\u22121.72; 95% CI, \u22122.65, \u22120.79), and more depressive symptoms (\u03b2=0.94; 95% CI, 0.51, 1.38). A nonsignificant trend toward lower physical functioning (\u03b2=\u22120.87; 95% CI, \u22121.95, 0.20) was observed. In sex-stratified analyses, the relationship between SS and outcomes was stronger for women than for men, with a significant SS-by-sex interaction for disease-specific quality of life, physical functioning, and depressive symptoms (all\n            <jats:italic>P<\/jats:italic>\n            &lt;0.02).\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Conclusions\u2014<\/jats:italic>\n            <\/jats:bold>\n            Lower SS is associated with worse health status and more depressive symptoms over the first year of acute myocardial infarction recovery, particularly for women.\n          <\/jats:p>","DOI":"10.1161\/circoutcomes.109.899815","type":"journal-article","created":{"date-parts":[[2010,2,17]],"date-time":"2010-02-17T05:10:10Z","timestamp":1266383410000},"page":"143-150","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":82,"title":["The Role of Social Support in Health Status and Depressive Symptoms After Acute Myocardial Infarction"],"prefix":"10.1161","volume":"3","author":[{"given":"Erica C.","family":"Leifheit-Limson","sequence":"first","affiliation":[{"name":"From Yale University (E.C.L.-L., S.V.K., H.L., J.H.L.), New Haven, Conn; Saint Luke\u2019s Mid America Heart Institute (K.J.R., P.G.J., D.M.B., J.A.S.), Kansas City, Mo; Emory University (S.P.), Atlanta, Ga; University of Colorado-Denver (P.N.P.), Aurora, Colo; Denver Health Medical Center (P.N.P.), Denver, Colo; and University of Missouri\u2013Kansas City (J.A.S.), Kansas City, Mo."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberly J.","family":"Reid","sequence":"additional","affiliation":[{"name":"From Yale University (E.C.L.-L., S.V.K., H.L., J.H.L.), New Haven, Conn; Saint Luke\u2019s Mid America Heart Institute (K.J.R., P.G.J., D.M.B., J.A.S.), Kansas City, Mo; Emory University (S.P.), Atlanta, Ga; University of Colorado-Denver (P.N.P.), Aurora, Colo; Denver Health Medical Center (P.N.P.), Denver, Colo; and University of Missouri\u2013Kansas City (J.A.S.), Kansas City, Mo."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stanislav V.","family":"Kasl","sequence":"additional","affiliation":[{"name":"From Yale University (E.C.L.-L., S.V.K., H.L., J.H.L.), New Haven, Conn; Saint Luke\u2019s Mid America Heart Institute (K.J.R., P.G.J., D.M.B., J.A.S.), Kansas City, Mo; Emory University (S.P.), Atlanta, Ga; University of Colorado-Denver (P.N.P.), Aurora, Colo; Denver Health Medical Center (P.N.P.), Denver, Colo; and University of Missouri\u2013Kansas City (J.A.S.), Kansas City, Mo."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haiqun","family":"Lin","sequence":"additional","affiliation":[{"name":"From Yale University (E.C.L.-L., S.V.K., H.L., J.H.L.), New Haven, Conn; Saint Luke\u2019s Mid America Heart Institute (K.J.R., P.G.J., D.M.B., J.A.S.), Kansas City, Mo; Emory University (S.P.), Atlanta, Ga; University of Colorado-Denver (P.N.P.), Aurora, Colo; Denver Health Medical Center (P.N.P.), Denver, Colo; and University of Missouri\u2013Kansas City (J.A.S.), Kansas City, Mo."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip G.","family":"Jones","sequence":"additional","affiliation":[{"name":"From Yale University (E.C.L.-L., S.V.K., H.L., J.H.L.), New Haven, Conn; Saint Luke\u2019s Mid America Heart Institute (K.J.R., P.G.J., D.M.B., J.A.S.), Kansas City, Mo; Emory University (S.P.), Atlanta, Ga; University of Colorado-Denver (P.N.P.), Aurora, Colo; Denver Health Medical Center (P.N.P.), Denver, Colo; and University of Missouri\u2013Kansas City (J.A.S.), Kansas City, Mo."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donna M.","family":"Buchanan","sequence":"additional","affiliation":[{"name":"From Yale University (E.C.L.-L., S.V.K., H.L., J.H.L.), New Haven, Conn; Saint Luke\u2019s Mid America Heart Institute (K.J.R., P.G.J., D.M.B., J.A.S.), Kansas City, Mo; Emory University (S.P.), Atlanta, Ga; University of Colorado-Denver (P.N.P.), Aurora, Colo; Denver Health Medical Center (P.N.P.), Denver, Colo; and University of Missouri\u2013Kansas City (J.A.S.), Kansas City, Mo."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susmita","family":"Parashar","sequence":"additional","affiliation":[{"name":"From Yale University (E.C.L.-L., S.V.K., H.L., J.H.L.), New Haven, Conn; Saint Luke\u2019s Mid America Heart Institute (K.J.R., P.G.J., D.M.B., J.A.S.), Kansas City, Mo; Emory University (S.P.), Atlanta, Ga; University of Colorado-Denver (P.N.P.), Aurora, Colo; Denver Health Medical Center (P.N.P.), Denver, Colo; and University of Missouri\u2013Kansas City (J.A.S.), Kansas City, Mo."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pamela N.","family":"Peterson","sequence":"additional","affiliation":[{"name":"From Yale University (E.C.L.-L., S.V.K., H.L., J.H.L.), New Haven, Conn; Saint Luke\u2019s Mid America Heart Institute (K.J.R., P.G.J., D.M.B., J.A.S.), Kansas City, Mo; Emory University (S.P.), Atlanta, Ga; University of Colorado-Denver (P.N.P.), Aurora, Colo; Denver Health Medical Center (P.N.P.), Denver, Colo; and University of Missouri\u2013Kansas City (J.A.S.), Kansas City, Mo."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Spertus","sequence":"additional","affiliation":[{"name":"From Yale University (E.C.L.-L., S.V.K., H.L., J.H.L.), New Haven, Conn; Saint Luke\u2019s Mid America Heart Institute (K.J.R., P.G.J., D.M.B., J.A.S.), Kansas City, Mo; Emory University (S.P.), Atlanta, Ga; University of Colorado-Denver (P.N.P.), Aurora, Colo; Denver Health Medical Center (P.N.P.), Denver, Colo; and University of Missouri\u2013Kansas City (J.A.S.), Kansas City, Mo."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Judith H.","family":"Lichtman","sequence":"additional","affiliation":[{"name":"From Yale University (E.C.L.-L., S.V.K., H.L., J.H.L.), New Haven, Conn; Saint Luke\u2019s Mid America Heart Institute (K.J.R., P.G.J., D.M.B., J.A.S.), Kansas City, Mo; Emory University (S.P.), Atlanta, Ga; University of Colorado-Denver (P.N.P.), Aurora, Colo; Denver Health Medical Center (P.N.P.), Denver, Colo; and University of Missouri\u2013Kansas City (J.A.S.), Kansas City, Mo."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006842-199505000-00006"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.psy.0000188393.73571.0a"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF00844754"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0147-9563(95)80024-7"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1497.1997.07121.x"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(00)00961-9"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008960308011"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1067\/mhl.2002.129447"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.psy.0000116775.98593.f4"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.2190\/BY6D-LMK8-P8HT-DMP9"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpsychores.2005.06.080"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a112674"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a113387"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a113544"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a114977"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-117-12-1003"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1037\/0278-6133.12.5.376"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/0277-9536(94)00404-H"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.97.10.958"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.PSY.0000041546.04128.43"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.PSY.0000033122.09203.A3"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ypmed.2003.10.010"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.socscimed.2005.12.004"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1300\/J013v43n01_04"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11136-006-9162-4"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-007-0106-7"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2005.05.026"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-8703(00)90301-6"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1097\/00008483-200601000-00002"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(94)00397-9"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199603000-00003"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.01.099"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000020688.24874.90"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.105.536102"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1525-1497.2001.016009606.x"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.1093\/aje\/kwh090"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a116297"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1037\/0021-843X.106.3.478"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1002\/gps.590"},{"key":"e_1_3_2_40_2","doi-asserted-by":"crossref","unstructured":"Fairclough DL. Design and Analysis of Quality of Life Studies in Clinical Trials. Boca Raton: Chapman & Hall\/CRC; 2002.","DOI":"10.1201\/9781420035438"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000020805.31531.48"},{"key":"e_1_3_2_42_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.108.190769"},{"key":"e_1_3_2_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-7358(01)00102-7"},{"key":"e_1_3_2_44_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.289.23.3106"},{"key":"e_1_3_2_45_2","doi-asserted-by":"publisher","DOI":"10.1161\/circ.99.16.2192"},{"key":"e_1_3_2_46_2","doi-asserted-by":"publisher","DOI":"10.1207\/S15327957PSPR0601_1"},{"key":"e_1_3_2_47_2","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.59.2.115"},{"key":"e_1_3_2_48_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006842-199901000-00006"},{"key":"e_1_3_2_49_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.8.876"}],"container-title":["Circulation: Cardiovascular Quality and Outcomes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCOUTCOMES.109.899815","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T02:52:10Z","timestamp":1715568730000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCOUTCOMES.109.899815"}},"subtitle":["Evidence for a Stronger Relationship Among Women"],"short-title":[],"issued":{"date-parts":[[2010,3]]},"references-count":49,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,3]]}},"alternative-id":["10.1161\/CIRCOUTCOMES.109.899815"],"URL":"https:\/\/doi.org\/10.1161\/circoutcomes.109.899815","relation":{},"ISSN":["1941-7713","1941-7705"],"issn-type":[{"value":"1941-7713","type":"print"},{"value":"1941-7705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,3]]},"assertion":[{"value":"2010-02-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}