{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T13:46:22Z","timestamp":1780667182057,"version":"3.54.1"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Quality and Outcomes"],"published-print":{"date-parts":[[2013,7]]},"abstract":"<jats:sec>\n            <jats:title>Background\u2014<\/jats:title>\n            <jats:p>Little is known about the clinical features, procedural risks, or survival of patients receiving replacement versus new implantable cardioverter-defibrillators (ICDs).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods and Results\u2014<\/jats:title>\n            <jats:p>\n              Entries in the National Cardiovascular Data Registry (NCDR) ICD Registry from 2005 through 2010 were eligible for inclusion (n=463\u2009978). Baseline demographic data, clinical information, and procedural variables were compared between patients receiving new (n=359\u2009993; 77.6%) and replacement (n=103\u2009985; 22.4%) ICDs and entered into a propensity match model to determine adjusted survival rates. Patients receiving replacement ICDs were older (70.7 versus 67.5 years of age) and more likely to have atrial fibrillation (41.8% versus 31.4%;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001) and ventricular tachycardia (60.5% versus 33.9%;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001) compared with patients receiving new ICDs. Median battery life was only 4.6 years (25%\u201375% interquartile range, 3.7\u20135.8) for all replaced devices, 5.8 (25%\u201375% interquartile range, 4.2\u20137.5) for single-chamber, 5.1 (25%\u201375% interquartile range, 4.1\u20136.1) for dual-chamber, and 3.9 (25%\u201375% interquartile range, 3.2\u20134.6) years for biventricular devices. Patients receiving replacement ICDs had lower rates of index admission complications (0.9% versus 3.2%;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001) but greater risk for death compared receiving patients receiving new ICDs in unadjusted analysis (hazard ratio, 1.18; 95% confidence interval, 1.16\u20131.20;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.0001) and after propensity-score matching (hazard ratio, 1.28; 95% confidence interval, 1.25\u20131.30;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.0001).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>Patients receiving replacement ICDs are older and at greater risk for death compared with those receiving initial ICD implants. The battery life of initial ICDs is shorter than previously reported.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circoutcomes.111.000054","type":"journal-article","created":{"date-parts":[[2013,6,12]],"date-time":"2013-06-12T02:00:27Z","timestamp":1371002427000},"page":"488-497","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":62,"title":["Characteristics and Outcomes of Patients Receiving New and Replacement Implantable Cardioverter-Defibrillators"],"prefix":"10.1161","volume":"6","author":[{"given":"Daniel B.","family":"Kramer","sequence":"first","affiliation":[{"name":"From the Beth Israel Deaconess Medical Center, Boston, MA (D.B.K., A.E.B., M.E.J., P.J.Z., M.R.R., S.L.M.); Harvard Medical School, Boston, MA (D.B.K., P.A.N., A.E.B., M.E.J., S.-L.N., P.J.Z., M.R.R., S.L.M.); Mid-America Heart Institute, Kansas City, MO (K.F.K., J.A.S.); Massachusetts General Hospital, Boston (P.A.N.); Hebrew SeniorLife Institute for Aging Research, Boston, MA (D.B.K., S.L.M.); and Harvard School of Public Health, Boston, MA (S.-L.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin F.","family":"Kennedy","sequence":"additional","affiliation":[{"name":"From the Beth Israel Deaconess Medical Center, Boston, MA (D.B.K., A.E.B., M.E.J., P.J.Z., M.R.R., S.L.M.); Harvard Medical School, Boston, MA (D.B.K., P.A.N., A.E.B., M.E.J., S.-L.N., P.J.Z., M.R.R., S.L.M.); Mid-America Heart Institute, Kansas City, MO (K.F.K., J.A.S.); Massachusetts General Hospital, Boston (P.A.N.); Hebrew SeniorLife Institute for Aging Research, Boston, MA (D.B.K., S.L.M.); and Harvard School of Public Health, Boston, MA (S.-L.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter A.","family":"Noseworthy","sequence":"additional","affiliation":[{"name":"From the Beth Israel Deaconess Medical Center, Boston, MA (D.B.K., A.E.B., M.E.J., P.J.Z., M.R.R., S.L.M.); Harvard Medical School, Boston, MA (D.B.K., P.A.N., A.E.B., M.E.J., S.-L.N., P.J.Z., M.R.R., S.L.M.); Mid-America Heart Institute, Kansas City, MO (K.F.K., J.A.S.); Massachusetts General Hospital, Boston (P.A.N.); Hebrew SeniorLife Institute for Aging Research, Boston, MA (D.B.K., S.L.M.); and Harvard School of Public Health, Boston, MA (S.-L.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfred E.","family":"Buxton","sequence":"additional","affiliation":[{"name":"From the Beth Israel Deaconess Medical Center, Boston, MA (D.B.K., A.E.B., M.E.J., P.J.Z., M.R.R., S.L.M.); Harvard Medical School, Boston, MA (D.B.K., P.A.N., A.E.B., M.E.J., S.-L.N., P.J.Z., M.R.R., S.L.M.); Mid-America Heart Institute, Kansas City, MO (K.F.K., J.A.S.); Massachusetts General Hospital, Boston (P.A.N.); Hebrew SeniorLife Institute for Aging Research, Boston, MA (D.B.K., S.L.M.); and Harvard School of Public Health, Boston, MA (S.-L.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark E.","family":"Josephson","sequence":"additional","affiliation":[{"name":"From the Beth Israel Deaconess Medical Center, Boston, MA (D.B.K., A.E.B., M.E.J., P.J.Z., M.R.R., S.L.M.); Harvard Medical School, Boston, MA (D.B.K., P.A.N., A.E.B., M.E.J., S.-L.N., P.J.Z., M.R.R., S.L.M.); Mid-America Heart Institute, Kansas City, MO (K.F.K., J.A.S.); Massachusetts General Hospital, Boston (P.A.N.); Hebrew SeniorLife Institute for Aging Research, Boston, MA (D.B.K., S.L.M.); and Harvard School of Public Health, Boston, MA (S.-L.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sharon-Lise","family":"Normand","sequence":"additional","affiliation":[{"name":"From the Beth Israel Deaconess Medical Center, Boston, MA (D.B.K., A.E.B., M.E.J., P.J.Z., M.R.R., S.L.M.); Harvard Medical School, Boston, MA (D.B.K., P.A.N., A.E.B., M.E.J., S.-L.N., P.J.Z., M.R.R., S.L.M.); Mid-America Heart Institute, Kansas City, MO (K.F.K., J.A.S.); Massachusetts General Hospital, Boston (P.A.N.); Hebrew SeniorLife Institute for Aging Research, Boston, MA (D.B.K., S.L.M.); and Harvard School of Public Health, Boston, MA (S.-L.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John A.","family":"Spertus","sequence":"additional","affiliation":[{"name":"From the Beth Israel Deaconess Medical Center, Boston, MA (D.B.K., A.E.B., M.E.J., P.J.Z., M.R.R., S.L.M.); Harvard Medical School, Boston, MA (D.B.K., P.A.N., A.E.B., M.E.J., S.-L.N., P.J.Z., M.R.R., S.L.M.); Mid-America Heart Institute, Kansas City, MO (K.F.K., J.A.S.); Massachusetts General Hospital, Boston (P.A.N.); Hebrew SeniorLife Institute for Aging Research, Boston, MA (D.B.K., S.L.M.); and Harvard School of Public Health, Boston, MA (S.-L.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter J.","family":"Zimetbaum","sequence":"additional","affiliation":[{"name":"From the Beth Israel Deaconess Medical Center, Boston, MA (D.B.K., A.E.B., M.E.J., P.J.Z., M.R.R., S.L.M.); Harvard Medical School, Boston, MA (D.B.K., P.A.N., A.E.B., M.E.J., S.-L.N., P.J.Z., M.R.R., S.L.M.); Mid-America Heart Institute, Kansas City, MO (K.F.K., J.A.S.); Massachusetts General Hospital, Boston (P.A.N.); Hebrew SeniorLife Institute for Aging Research, Boston, MA (D.B.K., S.L.M.); and Harvard School of Public Health, Boston, MA (S.-L.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew R.","family":"Reynolds","sequence":"additional","affiliation":[{"name":"From the Beth Israel Deaconess Medical Center, Boston, MA (D.B.K., A.E.B., M.E.J., P.J.Z., M.R.R., S.L.M.); Harvard Medical School, Boston, MA (D.B.K., P.A.N., A.E.B., M.E.J., S.-L.N., P.J.Z., M.R.R., S.L.M.); Mid-America Heart Institute, Kansas City, MO (K.F.K., J.A.S.); Massachusetts General Hospital, Boston (P.A.N.); Hebrew SeniorLife Institute for Aging Research, Boston, MA (D.B.K., S.L.M.); and Harvard School of Public Health, Boston, MA (S.-L.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susan L.","family":"Mitchell","sequence":"additional","affiliation":[{"name":"From the Beth Israel Deaconess Medical Center, Boston, MA (D.B.K., A.E.B., M.E.J., P.J.Z., M.R.R., S.L.M.); Harvard Medical School, Boston, MA (D.B.K., P.A.N., A.E.B., M.E.J., S.-L.N., P.J.Z., M.R.R., S.L.M.); Mid-America Heart Institute, Kansas City, MO (K.F.K., J.A.S.); Massachusetts General Hospital, Boston (P.A.N.); Hebrew SeniorLife Institute for Aging Research, Boston, MA (D.B.K., S.L.M.); and Harvard School of Public Health, Boston, MA (S.-L.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2010.07.015"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.110.959676"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/circep.110.959791"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.110.976076"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCUALTIONAHA.108.189742"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.08.058"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.108.816884"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.04.095"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2011.08.031"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2005.04.009"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp1111467"},{"key":"e_1_3_3_13_2","unstructured":"National Cardiovascular Data Registry\u2014ICD Registry. http:\/\/chapteraffairs.acc.org\/quality\/accreg\/Documents\/Chapter%20Toolkit.pdf. 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