{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T17:44:06Z","timestamp":1781027046585,"version":"3.54.1"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Quality and Outcomes"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:sec>\n            <jats:title>Background\u2014<\/jats:title>\n            <jats:p>The use and popularity of the biphasic waveform defibrillator as a replacement for the monophasic waveform defibrillator are increasing, but it is unclear whether this can improve the rate of survival among out-of-hospital cardiac arrest patients. This study aimed to verify the hypothesis that the outcome of out-of-hospital cardiac arrest patients who received defibrillation shock with the biphasic waveform defibrillator was better than that of patients who received defibrillation shock with the monophasic defibrillator.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods and Results\u2014<\/jats:title>\n            <jats:p>\n              This prospective, nationwide, population-based, observational study included 21 172 out-of-hospital cardiac arrest patients with initial ventricular fibrillation or pulseless ventricular tachycardia from January 1, 2005, through December 31, 2007. Defibrillation shock was performed by monophasic defibrillator on 8224 (39%) patients and by biphasic defibrillator on 12 948 (61%) patients. The rate of survival at 1 month with minimal neurological impairment was 11.6% (951\/8192) in the monophasic defibrillator group and 12.8% (1653\/12 928) in the biphasic defibrillator group. Hierarchical logistic regression analysis using a generalized estimation equation showed no significant difference between the biphasic and monophasic groups in 1-month survival with minimal neurological impairment (adjusted odds ratio, 1.07; 95% confidence interval, 0.91\u20131.26;\n              <jats:italic>P<\/jats:italic>\n              =0.42). Confirmatory propensity score analyses showed similar results.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>Although monophasic defibrillators are being replaced by biphasic defibrillators, our nationwide population-based observational study failed to demonstrate a statistically significant association between defibrillation waveform and 1-month survival rate with minimal neurological impairment.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circoutcomes.112.965319","type":"journal-article","created":{"date-parts":[[2012,9,12]],"date-time":"2012-09-12T05:57:25Z","timestamp":1347429445000},"page":"689-696","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":9,"title":["Comparison of Outcomes After Use of Biphasic or Monophasic Defibrillators Among Out-of-Hospital Cardiac Arrest Patients"],"prefix":"10.1161","volume":"5","author":[{"given":"Seizan","family":"Tanabe","sequence":"first","affiliation":[{"name":"From the Emergency Life-Saving Technique Academy of Tokyo, Tokyo, Japan (S.T.); Department of Health Management and Policy Graduate School of Medicine, The University of Tokyo, Tokyo, Japan (H.H., H.Yasunaga); Department of Public Health, Health Management and Policy, Nara Medical University School of Medicine, Nara, Japan (T.O., M.A., T.I.); Department of Planning, Information and Management, The University of Tokyo Hospital, Tokyo, Japan (S.K.); Emergency Life-Saving Technique Academy of Kyushu,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideo","family":"Yasunaga","sequence":"additional","affiliation":[{"name":"From the Emergency Life-Saving Technique Academy of Tokyo, Tokyo, Japan (S.T.); Department of Health Management and Policy Graduate School of Medicine, The University of Tokyo, Tokyo, Japan (H.H., H.Yasunaga); Department of Public Health, Health Management and Policy, Nara Medical University School of Medicine, Nara, Japan (T.O., M.A., T.I.); Department of Planning, Information and Management, The University of Tokyo Hospital, Tokyo, Japan (S.K.); Emergency Life-Saving Technique Academy of Kyushu,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toshio","family":"Ogawa","sequence":"additional","affiliation":[{"name":"From the Emergency Life-Saving Technique Academy of Tokyo, Tokyo, Japan (S.T.); Department of Health Management and Policy Graduate School of Medicine, The University of Tokyo, Tokyo, Japan (H.H., H.Yasunaga); Department of Public Health, Health Management and Policy, Nara Medical University School of Medicine, Nara, Japan (T.O., M.A., T.I.); Department of Planning, Information and Management, The University of Tokyo Hospital, Tokyo, Japan (S.K.); Emergency Life-Saving Technique Academy of Kyushu,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soichi","family":"Koike","sequence":"additional","affiliation":[{"name":"From the Emergency Life-Saving Technique Academy of Tokyo, Tokyo, Japan (S.T.); Department of Health Management and Policy Graduate School of Medicine, The University of Tokyo, Tokyo, Japan (H.H., H.Yasunaga); Department of Public Health, Health Management and Policy, Nara Medical University School of Medicine, Nara, Japan (T.O., M.A., T.I.); Department of Planning, Information and Management, The University of Tokyo Hospital, Tokyo, Japan (S.K.); Emergency Life-Saving Technique Academy of Kyushu,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manabu","family":"Akahane","sequence":"additional","affiliation":[{"name":"From the Emergency Life-Saving Technique Academy of Tokyo, Tokyo, Japan (S.T.); Department of Health Management and Policy Graduate School of Medicine, The University of Tokyo, Tokyo, Japan (H.H., H.Yasunaga); Department of Public Health, Health Management and Policy, Nara Medical University School of Medicine, Nara, Japan (T.O., M.A., T.I.); Department of Planning, Information and Management, The University of Tokyo Hospital, Tokyo, Japan (S.K.); Emergency Life-Saving Technique Academy of Kyushu,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiromasa","family":"Horiguchi","sequence":"additional","affiliation":[{"name":"From the Emergency Life-Saving Technique Academy of Tokyo, Tokyo, Japan (S.T.); Department of Health Management and Policy Graduate School of Medicine, The University of Tokyo, Tokyo, Japan (H.H., H.Yasunaga); Department of Public Health, Health Management and Policy, Nara Medical University School of Medicine, Nara, Japan (T.O., M.A., T.I.); Department of Planning, Information and Management, The University of Tokyo Hospital, Tokyo, Japan (S.K.); Emergency Life-Saving Technique Academy of Kyushu,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tetsuo","family":"Hatanaka","sequence":"additional","affiliation":[{"name":"From the Emergency Life-Saving Technique Academy of Tokyo, Tokyo, Japan (S.T.); Department of Health Management and Policy Graduate School of Medicine, The University of Tokyo, Tokyo, Japan (H.H., H.Yasunaga); Department of Public Health, Health Management and Policy, Nara Medical University School of Medicine, Nara, Japan (T.O., M.A., T.I.); Department of Planning, Information and Management, The University of Tokyo Hospital, Tokyo, Japan (S.K.); Emergency Life-Saving Technique Academy of Kyushu,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroyuki","family":"Yokota","sequence":"additional","affiliation":[{"name":"From the Emergency Life-Saving Technique Academy of Tokyo, Tokyo, Japan (S.T.); Department of Health Management and Policy Graduate School of Medicine, The University of Tokyo, Tokyo, Japan (H.H., H.Yasunaga); Department of Public Health, Health Management and Policy, Nara Medical University School of Medicine, Nara, Japan (T.O., M.A., T.I.); Department of Planning, Information and Management, The University of Tokyo Hospital, Tokyo, Japan (S.K.); Emergency Life-Saving Technique Academy of Kyushu,..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoaki","family":"Imamura","sequence":"additional","affiliation":[{"name":"From the Emergency Life-Saving Technique Academy of Tokyo, Tokyo, Japan (S.T.); Department of Health Management and Policy Graduate School of Medicine, The University of Tokyo, Tokyo, Japan (H.H., H.Yasunaga); Department of Public Health, Health Management and Policy, Nara Medical University School of Medicine, Nara, Japan (T.O., M.A., T.I.); Department of Planning, Information and Management, The University of Tokyo Hospital, Tokyo, Japan (S.K.); Emergency Life-Saving Technique Academy of Kyushu,..."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.479915"},{"key":"e_1_3_3_3_2","first-page":"1","article-title":"Out-of-hospital cardiac arrest surveillance \u2014 Cardiac Arrest Registry to Enhance Survival (CARES), United States, October 1, 2005\u2013December 31, 2010.","volume":"60","author":"McNally B","year":"2011","unstructured":"McNally B, Robb R, Mehta M, Vellano K, Valderrama AL, Yoon PW, Sasson C, Crouch A, Perez AB, Merritt R, Kellermann A. 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