{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,13]],"date-time":"2026-03-13T16:38:18Z","timestamp":1773419898780,"version":"3.50.1"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Quality and Outcomes"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:sec>\n            <jats:title>Background\u2014<\/jats:title>\n            <jats:p>Prior studies have found that obese patients have paradoxically lower in-hospital mortality after non\u2013ST-segment\u2013elevation myocardial infarction than their normal-weight counterparts, yet whether these associations persist long term is unknown.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods and Results\u2014<\/jats:title>\n            <jats:p>We linked detailed clinical data for patients with non\u2013ST-segment\u2013elevation myocardial infarction aged \u226565 years in the Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes With Early Implementation of the American College of Cardiology\/American Heart Association Guidelines (CRUSADE) Registry to Medicare claims data to obtain longitudinal outcomes. Using height and weight measured on admission, patients were categorized into 6 body mass index (BMI [kilograms per meter squared]) groups. Multivariable Cox proportional hazards models were used to estimate the association between BMI and (1) all-cause mortality, (2) all-cause readmission, (3) cardiovascular readmission, and (4) noncardiovascular readmission for 3 years after hospital discharge. Among older patients with non\u2013ST-segment\u2013elevation myocardial infarction (n=34 465), 36.3% were overweight and 27.7% were obese. Obese patients were younger and more likely to have hypertension, diabetes mellitus, and dyslipidemia than normal or underweight patients. Relative to normal-weight patients, long-term mortality was lower for patients classified as overweight (BMI, 25.0\u201329.9), obese class I (BMI, 30.0\u201334.9), and obese class II (BMI, 35.0\u201339.9), but not obese class III (BMI \u226540.0). In contrast, 3-year all-cause and cardiovascular readmission were similar across BMI categories. Relative to normal-weight patients, noncardiovascular readmissions were similar for obese class I but higher for obese class II and obese class III.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions\u2014<\/jats:title>\n            <jats:p>All-cause long-term mortality was generally lower for overweight and obese older patients after non\u2013ST-segment\u2013elevation myocardial infarction relative to those with normal weight. Longitudinal readmissions were similar or higher with increasing BMI.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circoutcomes.113.000421","type":"journal-article","created":{"date-parts":[[2013,12,11]],"date-time":"2013-12-11T03:52:49Z","timestamp":1386733969000},"page":"102-109","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":38,"title":["Association of Body Mass Index and Long-Term Outcomes in Older Patients With Non\u2013ST-Segment\u2013Elevation Myocardial Infarction"],"prefix":"10.1161","volume":"7","author":[{"given":"Emily C.","family":"O\u2019Brien","sequence":"first","affiliation":[{"name":"From the Departments of Clinical Pharmacology (E.C.O., K.P.A., M.T.R., E.D.P.) and Outcomes Research (S.A.P.) Duke Clinical Research Institute, Durham, NC; and Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark (E.L.F.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emil L.","family":"Fosbol","sequence":"additional","affiliation":[{"name":"From the Departments of Clinical Pharmacology (E.C.O., K.P.A., M.T.R., E.D.P.) and Outcomes Research (S.A.P.) Duke Clinical Research Institute, Durham, NC; and Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark (E.L.F.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. Andrew","family":"Peng","sequence":"additional","affiliation":[{"name":"From the Departments of Clinical Pharmacology (E.C.O., K.P.A., M.T.R., E.D.P.) and Outcomes Research (S.A.P.) Duke Clinical Research Institute, Durham, NC; and Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark (E.L.F.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen P.","family":"Alexander","sequence":"additional","affiliation":[{"name":"From the Departments of Clinical Pharmacology (E.C.O., K.P.A., M.T.R., E.D.P.) and Outcomes Research (S.A.P.) Duke Clinical Research Institute, Durham, NC; and Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark (E.L.F.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew T.","family":"Roe","sequence":"additional","affiliation":[{"name":"From the Departments of Clinical Pharmacology (E.C.O., K.P.A., M.T.R., E.D.P.) and Outcomes Research (S.A.P.) Duke Clinical Research Institute, Durham, NC; and Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark (E.L.F.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric D.","family":"Peterson","sequence":"additional","affiliation":[{"name":"From the Departments of Clinical Pharmacology (E.C.O., K.P.A., M.T.R., E.D.P.) and Outcomes Research (S.A.P.) Duke Clinical Research Institute, Durham, NC; and Department of Cardiology, Gentofte University Hospital, Hellerup, Denmark (E.L.F.)."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.167.16.1720"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9149(03)00031-6"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.165.1.55"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/81.3.543"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs217"},{"key":"e_1_3_4_7_2","first-page":"581","article-title":"Association of weight status with mortality in adults with incident diabetes.","volume":"308","author":"Carnethon MR","year":"2012","unstructured":"Carnethon MR, De Chavez PJ, Biggs ML, Lewis CE, Pankow JS, Bertoni AG, Golden SH, Liu K, Mukamal KJ, Campbell-Jenkins B, Dyer AR. 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