{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T20:35:43Z","timestamp":1788554143703,"version":"build-2803163510"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Quality and Outcomes"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:sec>\n            <jats:title>Background<\/jats:title>\n            <jats:p>Disability-adjusted life years (DALY) are a common public health metric used to consistently estimate and compare health loss because of both fatal and nonfatal disease burden. The annual number of DALY because of adult out-of-hospital cardiac arrest (OHCA) in the United States is unknown. Our objective was to estimate the DALY after adult nontraumatic, emergency medical services\u2013treated OHCA, and to compare OHCA DALY to other leading causes of death and disability in the US.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p>The DALY were calculated as the sum of years of life lost and years lived with disability. The years of life lost were calculated using all adult nontraumatic emergency medical services\u2013treated OHCA with complete data from the national Cardiac Arrest Registry to Enhance Survival database for 2016, and actuarial data for remaining life expectancy at the age of death. Cerebral performance category scores from the Cardiac Arrest Registry to Enhance Survival database and previously established disability weights were used to estimate years lived with disability. The cohort\u2019s calculated DALY were extrapolated to a national level to estimate total US DALY. Data were reported as total, mean, and DALY per 100\u2009000 individuals. A total of 59\u2009752 OHCA met study inclusion criteria. The DALY for the study population were 1\u2009194\u2009993 (years of life lost, 1\u2009194\u2009069; years lived with disability, 924) in 2016. The estimated total DALY following adult nontraumatic emergency medical services\u2013treated OHCA in the US were 4\u2009354 \u2009192 (years of life lost, 4\u2009350 \u2009825; years lived with disability, 3365) for the index year 2016. The rate of OHCA DALY were 1347 per 100\u2009000 population, which ranked third in the US behind ischemic heart disease (2447) and low back and neck pain (1565). Sensitivity analyses yielded similar findings.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p>Adult nontraumatic OHCA is a leading cause of annual DALY in the US and should be a focus of public health policy and resources.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circoutcomes.118.004677","type":"journal-article","created":{"date-parts":[[2019,3,12]],"date-time":"2019-03-12T12:29:43Z","timestamp":1552393783000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":68,"title":["Disability-Adjusted Life Years Following Adult Out-of-Hospital Cardiac Arrest in the United States"],"prefix":"10.1161","volume":"12","author":[{"given":"Ryan A.","family":"Coute","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, University of Alabama School of Medicine, Birmingham (R.A.C., M.C.K.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian H.","family":"Nathanson","sequence":"additional","affiliation":[{"name":"OptiStatim, LLC, Longmeadow, MA (B.H.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashish R.","family":"Panchal","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Ohio State University Wexner Medical Center, Columbus (A.R.P.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael C.","family":"Kurz","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, University of Alabama School of Medicine, Birmingham (R.A.C., M.C.K.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan L.","family":"Haas","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, University of Michigan, Ann Arbor (N.L.H., R.W.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bryan","family":"McNally","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Emory University, Atlanta, GA (B.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert W.","family":"Neumar","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, University of Michigan, Ann Arbor (N.L.H., R.W.N.)."},{"name":"Michigan Center for Integrative Research in Critical Care, University of Michigan, Ann Arbor (R.W.N.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy J.","family":"Mader","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, University of Massachusetts Medical School\u2014Baystate, Springfield (T.J.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"name":"for the CARES Surveillance Group","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.emc.2011.09.003"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000485"},{"key":"e_1_3_3_4_2","first-page":"49","volume-title":"In: Strategies to Improve Cardiac Arrest Survival: A Time to Act","author":"Committee on the Treatment of Cardiac Arrest","year":"2015","unstructured":"Committee on the Treatment of Cardiac Arrest: Current status and future directions; board on health sciences policy; institute of medicine. Graham, R, McCoy, MA, Schultz, AM, eds. In: Strategies to Improve Cardiac Arrest Survival: A Time to Act. Washington, DC: National Academies Press (US); 2015;49\u2013100."},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.113.001034"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)32130-X"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00038-014-0552-z"},{"key":"e_1_3_3_8_2","unstructured":"Global Health Data Exchange. Institutes for Health Metrics and Evaluation. http:\/\/ghdx.healthdata.org\/gbd-results-tool. Accessed November 6 2017."},{"key":"e_1_3_3_9_2","unstructured":"Cardiac Arrest Registry to Enhance Survival. Data Sharing Policy. https:\/\/mycares.net\/sitepages\/datasharepolicy.jsp. 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