{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T01:54:12Z","timestamp":1790733252324,"version":"4.1.0"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Quality and Outcomes"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Restricting transcatheter aortic valve replacement (TAVR) to centers based on volume thresholds alone can potentially create unintended disparities in healthcare access. We aimed to compare the influence of population density in state of Florida in regard to access to TAVR, TAVR utilization rates, and in-hospital mortality.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods and Results:<\/jats:title>\n            <jats:p>\n              From 2011 to 2016, we used data from the Agency for Health Care Administration to calculate travel time and distance for each TAVR patient by comparing their home address to their TAVR facility ZIP code. Travel time and distance, TAVR rates, and mortality were compared across categories of low to high population density (population per square miles of land). Of the 6531 patients included, the mean (SD) age was 82 (9) years, 43% were female and 91% were White. Patients residing in the lowest category (&lt;50\/square miles) were younger, more likely to be men, and less likely to be a racial minority. Those residing in the lowest category density faced a longer unadjusted driving distances and times to their TAVR center (mean extra distance [miles]=43.5 [95% CI, 35.6\u201351.4];\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001; mean extra time (minutes)=45.6 [95% CI, 38.3\u201352.9],\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001). This association persisted regardless of the methods used to determine population density. Excluding uninhabitable land, there was a 7-fold difference in TAVR utilization rates in the lowest versus highest population density regions (7 versus 45 per 100\u2009000,\n              <jats:italic>P<\/jats:italic>\n              -for-pairwise-comparisons &lt;0.001) and increase in TAVR in-hospital mortality (adjusted OR, 6.13 [95% CI, 1.97\u201319.1];\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>Older patients living in rural counties in Florida face (1) significantly longer travel distances and times for TAVR, (2) lower TAVR utilization rates, and (3) higher adjusted TAVR mortality. These findings suggest that there are trade-offs between access to TAVR, its rate of utilization, and procedural mortality, all of which are important considerations when defining institutional and operator requirements for TAVR across the country.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circoutcomes.119.006245","type":"journal-article","created":{"date-parts":[[2020,8,19]],"date-time":"2020-08-19T19:40:47Z","timestamp":1597866047000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":31,"title":["Transcatheter Aortic Valve Replacement in Low-Population Density Areas"],"prefix":"10.1161","volume":"13","author":[{"given":"Abdulla A.","family":"Damluji","sequence":"first","affiliation":[{"name":"Inova Center of Outcomes Research, Inova Heart and Vascular Institute, Falls Church, VA (A.A.D., M.W.S., C.M.O., W.B.)."},{"name":"Division of Cardiology, Johns Hopkins University, Baltimore, MD (A.A.D., J.R.R.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"II","given":"Michael","family":"Fabbro","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, University of Miami, FL (M.F., R.H.E.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard H.","family":"Epstein","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, University of Miami, FL (M.F., R.H.E.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan","family":"Rayer","sequence":"additional","affiliation":[{"name":"Bureau of Economic and Business Research, University of Florida, Gainesville, FL (S.R., Y.W.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Wang","sequence":"additional","affiliation":[{"name":"Bureau of Economic and Business Research, University of Florida, Gainesville, FL (S.R., Y.W.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mauro","family":"Moscucci","sequence":"additional","affiliation":[{"name":"University of Michigan, Ann Arbor, MI (M.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2038-6070","authenticated-orcid":true,"given":"Mauricio G.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Cardiovascular Division, University of Miami, FL (M.G.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John D.","family":"Carroll","sequence":"additional","affiliation":[{"name":"Division of Cardiology, University of Colorado School of Medicine, Aurora, CO (J.D.C., J.C.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John C.","family":"Messenger","sequence":"additional","affiliation":[{"name":"Division of Cardiology, University of Colorado School of Medicine, Aurora, CO (J.D.C., J.C.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jon R.","family":"Resar","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Johns Hopkins University, Baltimore, MD (A.A.D., J.R.R.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Cohen","sequence":"additional","affiliation":[{"name":"University of Missouri-Kansas City School of Medicine, Kansas City, MO (D.J.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4305-5883","authenticated-orcid":true,"given":"Matthew W.","family":"Sherwood","sequence":"additional","affiliation":[{"name":"Inova Center of Outcomes Research, Inova Heart and Vascular Institute, Falls Church, VA (A.A.D., M.W.S., C.M.O., W.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher M.","family":"O\u2019Connor","sequence":"additional","affiliation":[{"name":"Inova Center of Outcomes Research, Inova Heart and Vascular Institute, Falls Church, VA (A.A.D., M.W.S., C.M.O., W.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne","family":"Batchelor","sequence":"additional","affiliation":[{"name":"Inova Center of Outcomes Research, Inova Heart and Vascular Institute, Falls Church, VA (A.A.D., M.W.S., C.M.O., W.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMp1508472"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2016.07.017"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2018.07.002"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.04.056"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.4606"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.283.19.2579"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/107755870105800205"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10900-013-9681-1"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0277-9536(99)00365-2"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2017.3766"},{"key":"e_1_3_4_12_2","first-page":"1","article-title":"Insurance coverage, access to care, and medical debt since the ACA: a look at California, Florida, New York, and Texas.","volume":"7","author":"Gunja MZ","year":"2017","unstructured":"Gunja, MZ, Collins, SR, Doty, MM, Beutel, S. Insurance coverage, access to care, and medical debt since the ACA: a look at California, Florida, New York, and Texas. Issue Brief (Commonw Fund). 2017;7:1\u201312.","journal-title":"Issue Brief (Commonw Fund)"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.2014.1414"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.12.2.7"},{"key":"e_1_3_4_15_2","volume-title":"State Standards For Access To Care In Medicaid Managed Care","author":"Murrin S","year":"2014","unstructured":"Murrin, S. State Standards For Access To Care In Medicaid Managed Care. 2014. Department of Health and Human Services. https:\/\/oig.hhs.gov\/oei\/reports\/oei-02-11-00320.pdf. Accessed April 2020."},{"key":"e_1_3_4_16_2","unstructured":"Rayer S Wang Y. Measuring Population Density For Counties In Florida. Bureau of Business and Economic Research. 2104. https:\/\/www.bebr.ufl.edu\/population\/website-article\/measuring-population-density-counties-florida. Accessed April 2020."},{"key":"e_1_3_4_17_2","volume-title":"Standard Populations Data","unstructured":"Standard Populations Data. National Cancer Institute. https:\/\/seer.cancer.gov\/stdpopulations\/stdpop.19ages.html. Accessed April 2020."},{"key":"e_1_3_4_18_2","volume-title":"Distance Matrix API","unstructured":"Distance Matrix API. Google. https:\/\/developers.google.com\/maps\/documentation\/distance-matrix\/start. Accessed April 2020."},{"key":"e_1_3_4_19_2","unstructured":"https:\/\/www.census.gov\/programs-surveys\/geography\/geographies\/reference-maps.html. Accessed April 2020."},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1186\/1476-072X-3-21"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1093\/jamia\/ocw181"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.03.074"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2014.07.051"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa1901109"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.113.000370"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2017.06.020"},{"key":"e_1_3_4_27_2","unstructured":"National Healthcare Quality and Disparities Report Chartbook on Rural Health Care. Rockville MD: Agency for Healthcare Research and Quality. 2017;AHRQ Pub. No. 17(18)-0001-2-EF. https:\/\/www.ahrq.gov\/sites\/default\/files\/wysiwyg\/research\/findings\/nhqrdr\/chartbooks\/qdr-ruralhealthchartbook-update.pdf"},{"key":"e_1_3_4_28_2","first-page":"11","article-title":"Clinton\u2019s \u2018Medicare for More\u2019 not such an easy cure.","volume":"25","author":"Kirkner RM","year":"2016","unstructured":"Kirkner, RM. Clinton\u2019s \u2018Medicare for More\u2019 not such an easy cure. Manag Care. 2016;25:11\u201312.","journal-title":"Manag Care"},{"key":"e_1_3_4_29_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2017.8336"},{"key":"e_1_3_4_30_2","doi-asserted-by":"publisher","DOI":"10.1177\/107755879505200406"}],"container-title":["Circulation: Cardiovascular Quality and Outcomes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCOUTCOMES.119.006245","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T03:35:02Z","timestamp":1715571302000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCOUTCOMES.119.006245"}},"subtitle":["Assessing Healthcare Access for Older Adults With Severe Aortic Stenosis"],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":29,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2020,8]]}},"alternative-id":["10.1161\/CIRCOUTCOMES.119.006245"],"URL":"https:\/\/doi.org\/10.1161\/circoutcomes.119.006245","relation":{},"ISSN":["1941-7713","1941-7705"],"issn-type":[{"value":"1941-7713","type":"print"},{"value":"1941-7705","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8]]},"assertion":[{"value":"2019-10-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-04-28","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-08-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e006245"}}