{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T07:35:17Z","timestamp":1787816117244,"version":"build-2784847793"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Cardiovascular Quality and Outcomes"],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Despite the benefits of novel therapeutics, inequitable diffusion of new technologies may generate disparities. We examined the growth of transcatheter aortic valve replacement (TAVR) in the United States to understand the characteristics of hospitals that developed TAVR programs and the socioeconomic status of patients these hospitals served.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>We identified fee-for-service Medicare beneficiaries aged 66 years or older who underwent TAVR between January 1, 2012, and December 31, 2018, and hospitals that developed TAVR programs (defined as performing \u226510 TAVRs over the study period). We used linear regression models to compare socioeconomic characteristics of patients treated at hospitals that did and did not establish TAVR programs and described the association between core-based statistical area level markers of socioeconomic status and TAVR rates.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>\n              Between 2012 and 2018, 583 hospitals developed new TAVR programs, including 572 (98.1%) in metropolitan areas, and 293 (50.3%) in metropolitan areas with preexisting TAVR programs. Compared with hospitals that did not start TAVR programs, hospitals that did start TAVR programs treated fewer patients with dual eligibility for Medicaid (difference of \u22122.83% [95% CI, \u22123.78% to \u22121.89%],\n              <jats:italic>P<\/jats:italic>\n              \u22640.01), higher median household incomes (difference $2447 [95% CI, $1348\u2013$3547],\n              <jats:italic>P<\/jats:italic>\n              =0.03), and from areas with lower distressed communities index scores (difference \u22124.02 units [95% CI, \u22125.43 to \u22122.61],\n              <jats:italic>P<\/jats:italic>\n              \u22640.01). After adjusting for the age, clinical comorbidities, race and ethnicity and socioeconomic status, areas with TAVR programs had higher rates of TAVR and TAVR rates per 100\u2009000 Medicare beneficiaries were higher in core-based statistical areas with fewer dual eligible patients, higher median income, and lower distressed communities index scores.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>During the initial growth phase of TAVR programs in the United States, hospitals serving wealthier patients were more likely to start programs. This pattern of growth has led to inequities in the dispersion of TAVR, with lower rates in poorer communities.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circoutcomes.121.008260","type":"journal-article","created":{"date-parts":[[2021,10,21]],"date-time":"2021-10-21T09:00:15Z","timestamp":1634806815000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":51,"title":["Socioeconomic and Geographic Characteristics of Hospitals Establishing Transcatheter Aortic Valve Replacement Programs, 2012\u20132018"],"prefix":"10.1161","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7227-6423","authenticated-orcid":true,"given":"Ashwin S.","family":"Nathan","sequence":"first","affiliation":[{"name":"Division of Cardiology (A.S.N., S.A.M.K., E.J.D., L.A.E., H.C.H., J.G., A.C.F.), Hospital of the University of Pennsylvania, Philadelphia."},{"name":"Penn Cardiovascular Outcomes, Quality, and Evaluative Research Center (A.S.N., L.Y., N.Y., S.A.M.K., E.J.D., L.A.E., N.D.D., P.W.G., J.G., A.C.F.), University of Pennsylvania, Philadelphia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9267-6531","authenticated-orcid":true,"given":"Lin","family":"Yang","sequence":"additional","affiliation":[{"name":"Penn Cardiovascular Outcomes, Quality, and Evaluative Research Center (A.S.N., L.Y., N.Y., S.A.M.K., E.J.D., L.A.E., N.D.D., P.W.G., J.G., A.C.F.), University of Pennsylvania, Philadelphia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3997-5860","authenticated-orcid":true,"given":"Nancy","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1345-3004","authenticated-orcid":true,"given":"Sameed Ahmed M.","family":"Khatana","sequence":"additional","affiliation":[{"name":"Division of Cardiology (A.S.N., S.A.M.K., E.J.D., L.A.E., H.C.H., J.G., A.C.F.), Hospital of the University of Pennsylvania, Philadelphia."},{"name":"Penn Cardiovascular Outcomes, Quality, and Evaluative Research Center (A.S.N., L.Y., N.Y., S.A.M.K., E.J.D., L.A.E., N.D.D., P.W.G., J.G., A.C.F.), University of Pennsylvania, Philadelphia."},{"name":"Leonard Davis Institute of Health Economics (A.S.N., L.Y., S.A.M.K., E.J.D., L.A.E., N.D.D., P.W.G., J.G., A.C.F.), University of Pennsylvania, Philadelphia."},{"name":"Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA (S.A.M.K., P.W.G., J.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elias J.","family":"Dayoub","sequence":"additional","affiliation":[{"name":"Division of Cardiology (A.S.N., S.A.M.K., E.J.D., L.A.E., H.C.H., J.G., A.C.F.), Hospital of the University of Pennsylvania, Philadelphia."},{"name":"Penn Cardiovascular Outcomes, Quality, and Evaluative Research Center (A.S.N., L.Y., N.Y., S.A.M.K., E.J.D., L.A.E., N.D.D., P.W.G., J.G., A.C.F.), University of Pennsylvania, Philadelphia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren A.","family":"Eberly","sequence":"additional","affiliation":[{"name":"Division of Cardiology (A.S.N., S.A.M.K., E.J.D., L.A.E., H.C.H., J.G., A.C.F.), Hospital of the University of Pennsylvania, Philadelphia."},{"name":"Penn Cardiovascular Outcomes, Quality, and Evaluative Research Center (A.S.N., L.Y., N.Y., S.A.M.K., E.J.D., L.A.E., N.D.D., P.W.G., J.G., A.C.F.), University of Pennsylvania, Philadelphia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1599-2957","authenticated-orcid":true,"given":"Sreekanth","family":"Vemulapalli","sequence":"additional","affiliation":[{"name":"Duke Clinical Research Institute, Durham, NC (S.V.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8319-5637","authenticated-orcid":true,"given":"Suzanne J.","family":"Baron","sequence":"additional","affiliation":[{"name":"Lahey Hospital and Medical Center, Burlington, MA (S.J.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9163-724X","authenticated-orcid":true,"given":"David J.","family":"Cohen","sequence":"additional","affiliation":[{"name":"St. Francis Hospital, Roslyn, New York (D.J.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4456-5674","authenticated-orcid":true,"given":"Nimesh D.","family":"Desai","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery (N.D.D., J.E.B.), Hospital of the University of Pennsylvania, Philadelphia."},{"name":"Penn Cardiovascular Outcomes, Quality, and Evaluative Research Center (A.S.N., L.Y., N.Y., S.A.M.K., E.J.D., L.A.E., N.D.D., P.W.G., J.G., A.C.F.), University of Pennsylvania, Philadelphia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7145-0453","authenticated-orcid":true,"given":"Joseph E.","family":"Bavaria","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery (N.D.D., J.E.B.), Hospital of the University of Pennsylvania, Philadelphia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3322-9568","authenticated-orcid":true,"given":"Howard C.","family":"Herrmann","sequence":"additional","affiliation":[{"name":"Division of Cardiology (A.S.N., S.A.M.K., E.J.D., L.A.E., H.C.H., J.G., A.C.F.), Hospital of the University of Pennsylvania, Philadelphia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7374-4292","authenticated-orcid":true,"given":"Peter W.","family":"Groeneveld","sequence":"additional","affiliation":[{"name":"Penn Cardiovascular Outcomes, Quality, and Evaluative Research Center (A.S.N., L.Y., N.Y., S.A.M.K., E.J.D., L.A.E., N.D.D., P.W.G., J.G., A.C.F.), University of Pennsylvania, Philadelphia."},{"name":"Leonard Davis Institute of Health Economics (A.S.N., L.Y., S.A.M.K., E.J.D., L.A.E., N.D.D., P.W.G., J.G., A.C.F.), University of Pennsylvania, Philadelphia."},{"name":"Corporal Michael J. 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