{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T11:23:34Z","timestamp":1791890614477,"version":"4.3.4"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:00:00Z","timestamp":1777593600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circ: Population Health and Outcomes"],"published-print":{"date-parts":[[2026,5]]},"abstract":"<jats:sec>\n                    <jats:title>BACKGROUND:<\/jats:title>\n                    <jats:p>This trial aimed to test the effectiveness of a data-driven quality improvement program in primary care on cardiovascular hospitalizations, major adverse cardiovascular events (MACE), risk factor profiles, and medication prescriptions at 24 months in people with coronary heart disease (CHD) compared with standard care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS:<\/jats:title>\n                    <jats:p>A single-blind, cluster randomized controlled trial recruiting Australian primary care practices (2019\u20132022) was conducted. Practices using compliant data extraction software and having \u2265200 adult patients annually with CHD were the units of randomization, and adults with CHD (who visited their general practitioner in the past 12 months) were the units of analysis. Practices were randomized to intervention (12-month data-driven quality improvement including benchmarking, monthly reporting, and improvement planning) or control (standard care). The primary outcome was the proportion of participants who had unplanned cardiovascular disease hospitalizations at 24 months. Secondary outcomes were MACE, medication prescriptions, risk factor targets, and management planning. Data were extracted from electronic records linked to administrative data.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS:<\/jats:title>\n                    <jats:p>A total of 51 primary care practices participated, resulting in a patient cohort of 7864. The mean age of the patient cohort was 71.9 (\u00b111.8) years, 68% were men, and 24% had a prior myocardial infarction. At 24 months, there was no significant difference between the groups for unplanned cardiovascular disease hospitalizations (relative risk, 0.91 [95% CI, 0.75\u20131.10]; MACE, 0.81 [95% CI, 0.61\u20131.07]; prescription of antiplatelet, 0.94 [95% CI, 0.79\u20131.13]), statin, 1.03 [95% CI, 0.97\u20131.09], angiotensin-converting enzyme or angiotensin receptor blocker, 1.00 [95% CI, 0.93\u20131.07]; risk factor targets for low-density lipoprotein cholesterol, 0.99 [95% CI, 0.86\u20131.13], systolic blood pressure, 0.97 [95% CI, 0.87\u20131.09], or smoking, 0.96 [95% CI, 0.57\u20131.59]; or management planning, 1.02 [95% CI, 0.64\u20131.63]).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS:<\/jats:title>\n                    <jats:p>A primary care, data-driven quality improvement program did not improve unplanned hospitalizations, MACE, medication prescriptions, achievement of risk factor targets, or management planning for people with CHD. Robust evidence for the use of a data-driven, collaborative approach to improving care for people with CHD in primary care remains elusive.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>REGISTRATION:<\/jats:title>\n                    <jats:p>\n                      URL:\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.anzctr.org.au\">https:\/\/www.anzctr.org.au<\/jats:ext-link>\n                      ; Unique identifier: ACTRN12619001790134.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/circoutcomes.125.012904","type":"journal-article","created":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T09:00:17Z","timestamp":1776243617000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Effectiveness of Data-Driven Quality Improvement on Hospitalizations and Health Outcomes for People With Coronary Heart Disease in Primary Care (QUEL): A Cluster Randomized Controlled Trial With 24-Month Follow-Up"],"prefix":"10.1161","volume":"19","clinical-trial-number":[{"clinical-trial-number":"actrn12619001790134","registry":"10.18810\/anzctr"}],"author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8707-5563","authenticated-orcid":true,"given":"Julie","family":"Redfern","sequence":"first","affiliation":[{"name":"Institute for Evidence-Based Healthcare (J.R.), Bond University, Gold Coast, Australia."},{"name":"Faculty of Medicine and Health (J.R.), Bond University, Gold Coast, Australia."},{"name":"Faculty of Medicine and Health (J.R., N.H., Q.T., C.K.C., R.G., D.M., T.U., K.H.), The University of Sydney, Australia."},{"name":"Susan Wakil School of Nursing and Midwifery (J.R., R.G.), The University of Sydney, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5444-1624","authenticated-orcid":true,"given":"Nashid","family":"Hafiz","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health (J.R., N.H., Q.T., C.K.C., R.G., D.M., T.U., K.H.), The University of Sydney, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8602-3347","authenticated-orcid":true,"given":"Qiang","family":"Tu","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health (J.R., N.H., Q.T., C.K.C., R.G., D.M., T.U., K.H.), The University of Sydney, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5291-8989","authenticated-orcid":true,"given":"Andrew","family":"Knight","sequence":"additional","affiliation":[{"name":"School of Health Sciences, Faculty of Medicine and Health, The University of Sydney, Australia (A.K.)."},{"name":"University of New South Wales, Sydney, Australia (A.K.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4582-7728","authenticated-orcid":true,"given":"Charlotte","family":"Hespe","sequence":"additional","affiliation":[{"name":"The University of Notre Dame, School of Medicine, Sydney, Australia (C.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4693-0038","authenticated-orcid":true,"given":"Clara K.","family":"Chow","sequence":"additional","affiliation":[{"name":"Faculty of Medicine and Health (J.R., N.H., Q.T., C.K.C., R.G., D.M., T.U., K.H.), The University of Sydney, Australia."},{"name":"Westmead Applied Research Centre, University of Sydney, Australia (C.K.C., T.U.)."},{"name":"Western Sydney Local Health District, Australia 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