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Growing insights into the temporal-spatial dynamics of immune responses across cardiovascular diseases have fueled the emergence of cardioimmunology as a promising field for interdisciplinary and translational research. The advent of high-throughput, single-cell multiomics has allowed for unprecedented advances in our understanding of cardiovascular immunology, among major causes of mortality, including myocardial infarction and ischemic heart disease, abdominal aortic aneurysm, and congenital heart disease. 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