{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T17:05:31Z","timestamp":1787504731889,"version":"build-2736575974"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"22","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[2006,6,6]]},"abstract":"<jats:p>\n                    <jats:bold>\n                      <jats:italic>Background\u2014<\/jats:italic>\n                    <\/jats:bold>\n                    The optimal treatment for dysfunctional right ventricle\u2013to\u2013pulmonary artery (RV-PA) conduits is unknown. Limited follow-up data on stenting of RV-PA conduits have been reported.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>\n                      <jats:italic>Methods and Results\u2014<\/jats:italic>\n                    <\/jats:bold>\n                    Between 1990 and 2004, deployment of balloon-expandable bare stents was attempted in 242 obstructed RV-PA conduits in 221 patients (median age, 6.7 years). Acute hemodynamic changes after stenting included significantly decreased RV systolic pressure (89\u00b118 to 65\u00b120 mm Hg,\n                    <jats:italic>P<\/jats:italic>\n                    &lt;0.001) and peak RV-PA gradient (59\u00b119 to 27\u00b114 mm Hg,\n                    <jats:italic>P<\/jats:italic>\n                    &lt;0.001). There were no deaths, and, aside from 5 malpositioned stents requiring surgical removal, there were no serious procedural complications. During follow-up of 4.0\u00b13.2 years, 9 patients died and 2 underwent heart transplantation, none related to catheterization or stent malfunction. During 155 follow-up catheterizations in 126 patients, the stent was redilated in 83 patients and additional stents were placed in 41. Stent fractures were diagnosed in 56 patients (43%) and associated with stent compression and substernal location but did not cause acute hemodynamic consequences. By Kaplan-Meier analysis, median freedom from conduit surgery after stenting was 2.7 years (3.9 years in patients &gt;5 years), with younger age, homograft conduit, conduit diameter \u226410 mm, diagnosis other than tetralogy of Fallot, Genesis stent, higher prestent RV:aortic pressure ratio, and stent malposition associated with shorter freedom from surgery. Tricuspid regurgitation and RV function did not change between stent implantation and subsequent surgery.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>\n                      <jats:italic>Conclusions\u2014<\/jats:italic>\n                    <\/jats:bold>\n                    Conduit stenting is an effective interim treatment for RV-PA conduit obstruction and prolongs conduit lifespan in most patients. Stent fractures were common but not associated with significant complications or earlier conduit reoperation.\n                  <\/jats:p>","DOI":"10.1161\/circulationaha.105.607127","type":"journal-article","created":{"date-parts":[[2006,5,31]],"date-time":"2006-05-31T05:09:16Z","timestamp":1149052156000},"page":"2598-2605","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":164,"title":["Endovascular Stenting of Obstructed Right Ventricle\u2013to\u2013Pulmonary Artery Conduits"],"prefix":"10.1161","volume":"113","author":[{"given":"Lynn F.","family":"Peng","sequence":"first","affiliation":[{"name":"From the Departments of Cardiology (L.F.P., D.B.M., A.W.N., A.J.P., A.C.M., J.E.L.) and Cardiac Surgery (E.A.B.), Children\u2019s Hospital Boston; and Departments of Pediatrics (L.F.P., D.B.M., A.W.N., A.J.P., A.C.M., J.E.L.) and Surgery (E.A.B.), Harvard Medical School, Boston, Mass."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doff B.","family":"McElhinney","sequence":"additional","affiliation":[{"name":"From the Departments of Cardiology (L.F.P., D.B.M., A.W.N., A.J.P., A.C.M., J.E.L.) and Cardiac Surgery (E.A.B.), Children\u2019s Hospital Boston; and Departments of Pediatrics (L.F.P., D.B.M., A.W.N., A.J.P., A.C.M., J.E.L.) and Surgery (E.A.B.), Harvard Medical School, Boston, Mass."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan W.","family":"Nugent","sequence":"additional","affiliation":[{"name":"From the Departments of Cardiology (L.F.P., D.B.M., A.W.N., A.J.P., A.C.M., J.E.L.) and Cardiac Surgery (E.A.B.), Children\u2019s Hospital Boston; and Departments of Pediatrics (L.F.P., D.B.M., A.W.N., A.J.P., A.C.M., J.E.L.) and Surgery (E.A.B.), Harvard Medical School, Boston, Mass."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J.","family":"Powell","sequence":"additional","affiliation":[{"name":"From the Departments of Cardiology (L.F.P., D.B.M., A.W.N., A.J.P., A.C.M., J.E.L.) and Cardiac Surgery (E.A.B.), Children\u2019s Hospital Boston; and Departments of Pediatrics (L.F.P., D.B.M., A.W.N., A.J.P., A.C.M., J.E.L.) and Surgery (E.A.B.), Harvard Medical School, Boston, Mass."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Audrey C.","family":"Marshall","sequence":"additional","affiliation":[{"name":"From the Departments of Cardiology (L.F.P., D.B.M., A.W.N., A.J.P., A.C.M., J.E.L.) and Cardiac Surgery (E.A.B.), Children\u2019s Hospital Boston; and Departments of Pediatrics (L.F.P., D.B.M., A.W.N., A.J.P., A.C.M., J.E.L.) and Surgery (E.A.B.), Harvard Medical School, Boston, Mass."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emile A.","family":"Bacha","sequence":"additional","affiliation":[{"name":"From the Departments of Cardiology (L.F.P., D.B.M., A.W.N., A.J.P., A.C.M., J.E.L.) and Cardiac Surgery (E.A.B.), Children\u2019s Hospital Boston; and Departments of Pediatrics (L.F.P., D.B.M., A.W.N., A.J.P., A.C.M., J.E.L.) and Surgery (E.A.B.), Harvard Medical School, Boston, Mass."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James E.","family":"Lock","sequence":"additional","affiliation":[{"name":"From the Departments of Cardiology (L.F.P., D.B.M., A.W.N., A.J.P., A.C.M., J.E.L.) and Cardiac Surgery (E.A.B.), Children\u2019s Hospital Boston; and Departments of Pediatrics (L.F.P., D.B.M., A.W.N., A.J.P., A.C.M., J.E.L.) and Surgery (E.A.B.), Harvard Medical School, Boston, Mass."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2005.04.014"},{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(02)04547-2"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(00)00628-X"},{"key":"e_1_3_2_4_2","first-page":"660","volume":"4","year":"1995","unstructured":"Tam RK, Tolan MJ, Zamvar VY, Slavik Z, Pickering R, Keeton BR, Salmon AP, Webber SA, Tsang V, Lamb RK. 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