{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T09:16:26Z","timestamp":1791105386288,"version":"4.1.0"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"17","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[2010,5,4]]},"abstract":"<jats:p>\n            <jats:bold>\n              <jats:italic>Background\u2014<\/jats:italic>\n            <\/jats:bold>\n            The purported advantage of ABO-incompatible (ABO-I) listing is to reduce wait times and wait-list mortality among infants awaiting heart transplantation. We sought to describe recent trends in ABO-I listing for US infants and to determine the impact of ABO-I listing on wait times and wait-list mortality.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Methods and Results\u2014<\/jats:italic>\n            <\/jats:bold>\n            In this multicenter retrospective cohort study using Organ Procurement and Transplant Network data, infants &lt;12 months of age listed for heart transplantation between 1999 and 2008 (n=1331) were analyzed. Infants listed for an ABO-I transplant were compared with a propensity score\u2013matched cohort listed for an ABO-compatible transplant through the use of a Cox shared-frailty model. The primary end point was time to heart transplantation. The percentage of eligible infants listed for an ABO-I heart increased from 0% before 2002 to 53% in 2007 (\n            <jats:italic>P<\/jats:italic>\n            &lt;0.001 for trend). Compared with infants listed exclusively for an ABO-compatible heart, infants with a primary ABO-I listing strategy (n=235) were more likely to be listed 1A, to have congenital heart disease and renal failure, and to require extracorporeal membrane oxygenation. For the propensity score\u2013matched groups (n=197 matched pairs), there was no difference in wait-list mortality; however, infants with blood type O assigned an ABO-I listing strategy were more likely to undergo heart transplantation by 30 days (31% versus 16%;\n            <jats:italic>P<\/jats:italic>\n            =0.007) with a less pronounced effect for infants with other blood types.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>Conclusions\u2014<\/jats:italic>\n            <\/jats:bold>\n            The proportion of US infants listed for an ABO-I heart transplantation has risen dramatically in recent years but still appears to be preferentially used for sicker infant candidates. The ABO-I listing strategy is associated with a higher likelihood of transplantation within 30 days for infants with blood group O and may benefit a broader range of transplantation candidates.\n          <\/jats:p>","DOI":"10.1161\/circulationaha.109.885756","type":"journal-article","created":{"date-parts":[[2010,4,20]],"date-time":"2010-04-20T03:44:56Z","timestamp":1271735096000},"page":"1926-1933","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":63,"title":["Impact of ABO-Incompatible Listing on Wait-List Outcomes Among Infants Listed for Heart Transplantation in the United States"],"prefix":"10.1161","volume":"121","author":[{"given":"Christopher S.","family":"Almond","sequence":"first","affiliation":[{"name":"From the Department of Cardiology (C.S.A., K.G., R.R.T., G.E.P., E.D.B., L.B.S., T.P.S.), Department of Cardiac Surgery (F.F.-T.), and Pediatric Transplant Center (C.S.A., E.D.B., L.B.S., F.F.-T., T.P.S.), Children\u2019s Hospital Boston; Departments of Pediatrics (C.S.A., R.R.T., E.D.B., L.B.S., T.P.S.) and Surgery (F.F.-T.), Harvard Medical School; and Department of Biostatistics (K.G.), Harvard School of Public Health, Boston, Mass."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimberlee","family":"Gauvreau","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology (C.S.A., K.G., R.R.T., G.E.P., E.D.B., L.B.S., T.P.S.), Department of Cardiac Surgery (F.F.-T.), and Pediatric Transplant Center (C.S.A., E.D.B., L.B.S., F.F.-T., T.P.S.), Children\u2019s Hospital Boston; Departments of Pediatrics (C.S.A., R.R.T., E.D.B., L.B.S., T.P.S.) and Surgery (F.F.-T.), Harvard Medical School; and Department of Biostatistics (K.G.), Harvard School of Public Health, Boston, Mass."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravi R.","family":"Thiagarajan","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology (C.S.A., K.G., R.R.T., G.E.P., E.D.B., L.B.S., T.P.S.), Department of Cardiac Surgery (F.F.-T.), and Pediatric Transplant Center (C.S.A., E.D.B., L.B.S., F.F.-T., T.P.S.), Children\u2019s Hospital Boston; Departments of Pediatrics (C.S.A., R.R.T., E.D.B., L.B.S., T.P.S.) and Surgery (F.F.-T.), Harvard Medical School; and Department of Biostatistics (K.G.), Harvard School of Public Health, Boston, Mass."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gary E.","family":"Piercey","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology (C.S.A., K.G., R.R.T., G.E.P., E.D.B., L.B.S., T.P.S.), Department of Cardiac Surgery (F.F.-T.), and Pediatric Transplant Center (C.S.A., E.D.B., L.B.S., F.F.-T., T.P.S.), Children\u2019s Hospital Boston; Departments of Pediatrics (C.S.A., R.R.T., E.D.B., L.B.S., T.P.S.) and Surgery (F.F.-T.), Harvard Medical School; and Department of Biostatistics (K.G.), Harvard School of Public Health, Boston, Mass."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth D.","family":"Blume","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology (C.S.A., K.G., R.R.T., G.E.P., E.D.B., L.B.S., T.P.S.), Department of Cardiac Surgery (F.F.-T.), and Pediatric Transplant Center (C.S.A., E.D.B., L.B.S., F.F.-T., T.P.S.), Children\u2019s Hospital Boston; Departments of Pediatrics (C.S.A., R.R.T., E.D.B., L.B.S., T.P.S.) and Surgery (F.F.-T.), Harvard Medical School; and Department of Biostatistics (K.G.), Harvard School of Public Health, Boston, Mass."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslie B.","family":"Smoot","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology (C.S.A., K.G., R.R.T., G.E.P., E.D.B., L.B.S., T.P.S.), Department of Cardiac Surgery (F.F.-T.), and Pediatric Transplant Center (C.S.A., E.D.B., L.B.S., F.F.-T., T.P.S.), Children\u2019s Hospital Boston; Departments of Pediatrics (C.S.A., R.R.T., E.D.B., L.B.S., T.P.S.) and Surgery (F.F.-T.), Harvard Medical School; and Department of Biostatistics (K.G.), Harvard School of Public Health, Boston, Mass."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis","family":"Fynn-Thompson","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology (C.S.A., K.G., R.R.T., G.E.P., E.D.B., L.B.S., T.P.S.), Department of Cardiac Surgery (F.F.-T.), and Pediatric Transplant Center (C.S.A., E.D.B., L.B.S., F.F.-T., T.P.S.), Children\u2019s Hospital Boston; Departments of Pediatrics (C.S.A., R.R.T., E.D.B., L.B.S., T.P.S.) and Surgery (F.F.-T.), Harvard Medical School; and Department of Biostatistics (K.G.), Harvard School of Public Health, Boston, Mass."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tajinder P.","family":"Singh","sequence":"additional","affiliation":[{"name":"From the Department of Cardiology (C.S.A., K.G., R.R.T., G.E.P., E.D.B., L.B.S., T.P.S.), Department of Cardiac Surgery (F.F.-T.), and Pediatric Transplant Center (C.S.A., E.D.B., L.B.S., F.F.-T., T.P.S.), Children\u2019s Hospital Boston; Departments of Pediatrics (C.S.A., R.R.T., E.D.B., L.B.S., T.P.S.) and Surgery (F.F.-T.), Harvard Medical School; and Department of Biostatistics (K.G.), Harvard School of Public Health, Boston, Mass."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_1_2","unstructured":"McDiarmid S. 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Doctors say girl in donor mix-up has permanent brain damage. The New York Times. March 12 2003."},{"key":"e_1_3_2_13_2","first-page":"4463","volume":"19","year":"1987","unstructured":"Paul LC, Baldwin WM III. Humoral rejection mechanisms and ABO incompatibility in renal transplantation. Transplant Proc. 1987; 19: 4463\u20134467.","journal-title":"Transplant Proc"},{"key":"e_1_3_2_14_2","first-page":"1255","volume":"16","year":"1997","unstructured":"Morrow WR, Naftel D, Chinnock R, Canter C, Boucek M, Zales V, McGiffin DC, Kirklin JK. Outcome of listing for heart transplantation in infants younger than six months: predictors of death and interval to transplantation: the Pediatric Heart Transplantation Study Group. J Heart Lung Transplant. 1997; 16: 1255\u20131266.","journal-title":"J Heart Lung Transplant"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-2498(02)00670-8"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.108.815712"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.107.709022"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2007.07.011"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2007.07.042"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2007.02040.x"},{"key":"e_1_3_2_21_2","first-page":"56649","year":"1999","unstructured":"Department of Health and Human Services. Organ Procurement and Transplantation Network: final rule. Vol Fed Reg 42 CFR. 1999: 56649\u201356661.","journal-title":"Vol Fed Reg 42 CFR"}],"container-title":["Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCULATIONAHA.109.885756","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T05:58:43Z","timestamp":1715579923000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCULATIONAHA.109.885756"}},"subtitle":["A Propensity Analysis"],"short-title":[],"issued":{"date-parts":[[2010,5,4]]},"references-count":21,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2010,5,4]]}},"alternative-id":["10.1161\/CIRCULATIONAHA.109.885756"],"URL":"https:\/\/doi.org\/10.1161\/circulationaha.109.885756","relation":{},"ISSN":["0009-7322","1524-4539"],"issn-type":[{"value":"0009-7322","type":"print"},{"value":"1524-4539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2010,5,4]]},"assertion":[{"value":"2010-04-19","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}