{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T13:57:47Z","timestamp":1782309467073,"version":"3.54.5"},"reference-count":36,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"25","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[2010,6,29]]},"abstract":"<jats:p>\n                    <jats:bold>\n                      <jats:italic>Background\u2014<\/jats:italic>\n                    <\/jats:bold>\n                    Thoracic endovascular aortic repair offers a less invasive approach for the treatment of ruptured descending thoracic aortic aneurysms (rDTAA). Due to the low incidence of this life-threatening condition, little is known about the outcomes of endovascular repair of rDTAA and the factors that affect these outcomes.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>\n                      <jats:italic>Methods and Results\u2014<\/jats:italic>\n                    <\/jats:bold>\n                    We retrospectively investigated the outcomes of 87 patients who underwent thoracic endovascular aortic repair for rDTAA at 7 referral centers between 2002 and 2009. The mean age was 69.8\u00b112 years and 69.0% of the patients were men. Hypovolemic shock was present in 21.8% of patients, and 40.2% were hemodynamically unstable. The 30-day mortality rate was 18.4%, and hypovolemic shock (odds ratio 4.75; 95% confidence interval, 1.37 to 16.5;\n                    <jats:italic>P<\/jats:italic>\n                    =0.014) and hemothorax at admission (odds ratio 6.65; 95% confidence interval, 1.64 to 27.1;\n                    <jats:italic>P<\/jats:italic>\n                    =0.008) were associated with increased 30-day mortality after adjusting for age. Stroke and paraplegia occurred each in 8.0%, and endoleak was diagnosed in 18.4% of patients within the first 30 days after thoracic endovascular aortic repair. Four additional patients died as a result of procedure-related complications during a median follow-up of 13 months; the estimated aneurysm-related mortality at 4 years was 25.4%.\n                  <\/jats:p>\n                  <jats:p>\n                    <jats:bold>\n                      <jats:italic>Conclusion\u2014<\/jats:italic>\n                    <\/jats:bold>\n                    Endovascular repair of rDTAA is associated with encouraging results. The endovascular approach was associated with considerable rates of neurological complications and procedure-related complications such as endoleak.\n                  <\/jats:p>","DOI":"10.1161\/circulationaha.109.908871","type":"journal-article","created":{"date-parts":[[2010,6,15]],"date-time":"2010-06-15T00:19:16Z","timestamp":1276561156000},"page":"2718-2723","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":52,"title":["Outcomes of Endovascular Repair of Ruptured Descending Thoracic Aortic Aneurysms"],"prefix":"10.1161","volume":"121","author":[{"given":"Frederik H.W.","family":"Jonker","sequence":"first","affiliation":[{"name":"From the Section of Vascular Surgery, Cardiothoracic Surgery and Interventional Radiology, Yale University School of Medicine, New Haven, and VA Connecticut Healthcare System, West Haven, Conn (F.H.W.J., B.E.M.); Erasmus University Medical Center (H.J.M.V.), Rotterdam; St. Antonius Hospital (R.H.H.), Nieuwegein; University Medical Center Utrecht (F.L.M.), Utrecht, the Netherlands; Baylor College of Medicine (P.H.L., H.A.), Houston, Tex; Policlinico San Donato IRCCS, Cardiovascular Center \u201cE. Malan,\u201d..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hence J.M.","family":"Verhagen","sequence":"additional","affiliation":[{"name":"From the Section of Vascular Surgery, Cardiothoracic Surgery and Interventional Radiology, Yale University School of Medicine, New Haven, and VA Connecticut Healthcare System, West Haven, Conn (F.H.W.J., B.E.M.); Erasmus University Medical Center (H.J.M.V.), Rotterdam; St. Antonius Hospital (R.H.H.), Nieuwegein; University Medical Center Utrecht (F.L.M.), Utrecht, the Netherlands; Baylor College of Medicine (P.H.L., H.A.), Houston, Tex; Policlinico San Donato IRCCS, Cardiovascular Center \u201cE. Malan,\u201d..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter H.","family":"Lin","sequence":"additional","affiliation":[{"name":"From the Section of Vascular Surgery, Cardiothoracic Surgery and Interventional Radiology, Yale University School of Medicine, New Haven, and VA Connecticut Healthcare System, West Haven, Conn (F.H.W.J., B.E.M.); Erasmus University Medical Center (H.J.M.V.), Rotterdam; St. Antonius Hospital (R.H.H.), Nieuwegein; University Medical Center Utrecht (F.L.M.), Utrecht, the Netherlands; Baylor College of Medicine (P.H.L., H.A.), Houston, Tex; Policlinico San Donato IRCCS, Cardiovascular Center \u201cE. Malan,\u201d..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin H.","family":"Heijmen","sequence":"additional","affiliation":[{"name":"From the Section of Vascular Surgery, Cardiothoracic Surgery and Interventional Radiology, Yale University School of Medicine, New Haven, and VA Connecticut Healthcare System, West Haven, Conn (F.H.W.J., B.E.M.); Erasmus University Medical Center (H.J.M.V.), Rotterdam; St. Antonius Hospital (R.H.H.), Nieuwegein; University Medical Center Utrecht (F.L.M.), Utrecht, the Netherlands; Baylor College of Medicine (P.H.L., H.A.), Houston, Tex; Policlinico San Donato IRCCS, Cardiovascular Center \u201cE. Malan,\u201d..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santi","family":"Trimarchi","sequence":"additional","affiliation":[{"name":"From the Section of Vascular Surgery, Cardiothoracic Surgery and Interventional Radiology, Yale University School of Medicine, New Haven, and VA Connecticut Healthcare System, West Haven, Conn (F.H.W.J., B.E.M.); Erasmus University Medical Center (H.J.M.V.), Rotterdam; St. Antonius Hospital (R.H.H.), Nieuwegein; University Medical Center Utrecht (F.L.M.), Utrecht, the Netherlands; Baylor College of Medicine (P.H.L., H.A.), Houston, Tex; Policlinico San Donato IRCCS, Cardiovascular Center \u201cE. Malan,\u201d..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. Anthony","family":"Lee","sequence":"additional","affiliation":[{"name":"From the Section of Vascular Surgery, Cardiothoracic Surgery and Interventional Radiology, Yale University School of Medicine, New Haven, and VA Connecticut Healthcare System, West Haven, Conn (F.H.W.J., B.E.M.); Erasmus University Medical Center (H.J.M.V.), Rotterdam; St. Antonius Hospital (R.H.H.), Nieuwegein; University Medical Center Utrecht (F.L.M.), Utrecht, the Netherlands; Baylor College of Medicine (P.H.L., H.A.), Houston, Tex; Policlinico San Donato IRCCS, Cardiovascular Center \u201cE. Malan,\u201d..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frans L.","family":"Moll","sequence":"additional","affiliation":[{"name":"From the Section of Vascular Surgery, Cardiothoracic Surgery and Interventional Radiology, Yale University School of Medicine, New Haven, and VA Connecticut Healthcare System, West Haven, Conn (F.H.W.J., B.E.M.); Erasmus University Medical Center (H.J.M.V.), Rotterdam; St. Antonius Hospital (R.H.H.), Nieuwegein; University Medical Center Utrecht (F.L.M.), Utrecht, the Netherlands; Baylor College of Medicine (P.H.L., H.A.), Houston, Tex; Policlinico San Donato IRCCS, Cardiovascular Center \u201cE. Malan,\u201d..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Husam","family":"Athamneh","sequence":"additional","affiliation":[{"name":"From the Section of Vascular Surgery, Cardiothoracic Surgery and Interventional Radiology, Yale University School of Medicine, New Haven, and VA Connecticut Healthcare System, West Haven, Conn (F.H.W.J., B.E.M.); Erasmus University Medical Center (H.J.M.V.), Rotterdam; St. Antonius Hospital (R.H.H.), Nieuwegein; University Medical Center Utrecht (F.L.M.), Utrecht, the Netherlands; Baylor College of Medicine (P.H.L., H.A.), Houston, Tex; Policlinico San Donato IRCCS, Cardiovascular Center \u201cE. Malan,\u201d..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bart E.","family":"Muhs","sequence":"additional","affiliation":[{"name":"From the Section of Vascular Surgery, Cardiothoracic Surgery and Interventional Radiology, Yale University School of Medicine, New Haven, and VA Connecticut Healthcare System, West Haven, Conn (F.H.W.J., B.E.M.); Erasmus University Medical Center (H.J.M.V.), Rotterdam; St. Antonius Hospital (R.H.H.), Nieuwegein; University Medical Center Utrecht (F.L.M.), Utrecht, the Netherlands; Baylor College of Medicine (P.H.L., H.A.), Houston, Tex; Policlinico San Donato IRCCS, Cardiovascular Center \u201cE. 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