{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T09:22:47Z","timestamp":1791883367077,"version":"4.3.4"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[2013,7,16]]},"abstract":"<jats:sec>\n                    <jats:title>Background\u2014<\/jats:title>\n                    <jats:p>Aortic root rupture is a major concern with balloon-expandable transcatheter aortic valve replacement (TAVR). We sought to identify predictors of aortic root rupture during balloon-expandable TAVR by using multidetector computed tomography.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results\u2014<\/jats:title>\n                    <jats:p>\n                      Thirty-one consecutive patients who experienced left ventricular outflow tract (LVOT)\/annular\/aortic contained\/noncontained rupture during TAVR were collected from 16 centers. A caliper-matched sample of 31 consecutive patients without annular rupture, who underwent pre-TAVR multidetector computed tomography served as a control group. Multidetector computed tomography assessment included short- and long-axis diameters and cross-sectional area of the sinotubular junction, annulus, and LVOT, and the presence, location, and extent of calcification of the LVOT, as well. There were no significant differences between the 2 groups in any preoperative clinical and echocardiographic variables. Aortic root rupture was identified in 20 patients and periaortic hematoma in 11. Patients with root rupture had a higher degree of subannular\/LVOT calcification quantified by the Agatston score (181.2\u00b1211.0 versus 22.5\u00b137.6,\n                      <jats:italic>P<\/jats:italic>\n                      &lt;0.001), and a higher frequency of \u226520% annular area oversizing (79.4% versus 29.0%,\n                      <jats:italic>P<\/jats:italic>\n                      &lt;0.001) and balloon postdilatation (22.6% versus 0.0%,\n                      <jats:italic>P<\/jats:italic>\n                      =0.005). In conditional logistic regression analysis for the matched data, moderate\/severe LVOT\/subannular calcifications (odds ratio, 10.92; 95% confidence interval, 3.23\u201336.91;\n                      <jats:italic>P<\/jats:italic>\n                      &lt;0.001) and prosthesis oversizing \u226520% (odds ratio, 8.38; 95% confidence interval, 2.67\u201326.33;\n                      <jats:italic>P<\/jats:italic>\n                      &lt;0.001) were associated with aortic root contained\/noncontained rupture.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions\u2014<\/jats:title>\n                    <jats:p>This study demonstrates that LVOT calcification and aggressive annular area oversizing are associated with an increased risk of aortic root rupture during TAVR with balloon-expandable prostheses. Larger studies are warranted to confirm these findings.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/circulationaha.113.002947","type":"journal-article","created":{"date-parts":[[2013,6,7]],"date-time":"2013-06-07T22:20:58Z","timestamp":1370643658000},"page":"244-253","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":553,"title":["Anatomical and Procedural Features Associated With Aortic Root Rupture During Balloon-Expandable Transcatheter Aortic Valve Replacement"],"prefix":"10.1161","volume":"128","author":[{"given":"Marco","family":"Barbanti","sequence":"first","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tae-Hyun","family":"Yang","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep","family":"Rod\u00e8s Cabau","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corrado","family":"Tamburino","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Wood","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hasan","family":"Jilaihawi","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Phillip","family":"Blanke","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raj R.","family":"Makkar","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azeem","family":"Latib","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Colombo","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giuseppe","family":"Tarantini","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rekha","family":"Raju","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald K.","family":"Binder","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giang","family":"Nguyen","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Melanie","family":"Freeman","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henrique B.","family":"Ribeiro","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samir","family":"Kapadia","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Min","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gudrun","family":"Feuchtner","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronen","family":"Gurtvich","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faisal","family":"Alqoofi","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Pelletier","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gian Paolo","family":"Ussia","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Massimo","family":"Napodano","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Fabio Sandoli","family":"de Brito","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susheel","family":"Kodali","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bjarne L.","family":"Norgaard","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolaj C.","family":"Hansson","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregor","family":"Pache","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio J.","family":"Canovas","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); Ferrarotto Hospital, University of Catania, Italy (M.B., C.T.); Busan Paik Hospital, Inje University, South Korea (T.-H.Y.); Quebec Heart &amp; Lung Institute, Laval University, Quebec City, Canada (J.R.C., H.B.R., J.M.); Cedars-Sinai Heart Institute, Los Angeles, CA (H.J., R.R.M.); University Hospital Freiburg, Germany (P.B., G.P.); EMO-GVM Centro Cuore Columbus and San Raffaele..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongbin","family":"Zhang","sequence":"additional","affiliation":[{"name":"From St Paul\u2019s Hospital, Vancouver, Canada (M.B., T.-H.Y., D.A.W., R.R., R.K.B., G.N.,M.F., H.Z., J.G.W., J.L.); 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