{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T00:53:16Z","timestamp":1792630396399,"version":"4.5.0"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[2014,8,26]]},"abstract":"<jats:sec>\n                    <jats:title>Background\u2014<\/jats:title>\n                    <jats:p>Our objective was to obtain contemporary lifetime estimates of congenital heart disease (CHD) prevalence using population-based data sources up to year 2010.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results\u2014<\/jats:title>\n                    <jats:p>The Quebec CHD database contains 28 years of longitudinal data on all individuals with CHD from 1983 to 2010. Severe CHD was defined as tetralogy of Fallot, truncus arteriosus, transposition complexes, endocardial cushion defects, and univentricular hearts. We used latent class bayesian models combining case definitions from physician claims, hospitalization, and surgical data to obtain point and interval prevalence estimates of CHD in the first year of life, in children (&lt;18 years of age) and in adults. We identified 107\u2009559 CHD patients from 1983 to 2010. Prevalence of CHD in the first year of life was 8.21 per 1000 live births (95% confidence interval, 7.47\u20139.02) from 1998 to 2005. In 2010, overall prevalence of CHD was 13.11 per 1000 (95% confidence interval, 12.43\u201313.81) in children and 6.12 per 1000 (95% confidence interval, 5.69\u20136.57) in adults. CHD prevalence increased by 11% in children and 57% in adults from 2000 to 2010. Prevalence in the severe CHD subgroup increased by 19% (95% confidence interval, 17%\u201321%) in children and 55% (51%\u201362%) in adults. By 2010, adults accounted for 66% of the entire CHD population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions\u2014<\/jats:title>\n                    <jats:p>With an increase of &gt;50% in CHD prevalence since 2000, by 2010 adults accounted for two thirds of patients with severe and other forms of CHD in the general population. Our findings should inform allocation of resources and the planning of workforce needs for the predominantly adult CHD population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/circulationaha.113.008396","type":"journal-article","created":{"date-parts":[[2014,6,19]],"date-time":"2014-06-19T01:11:46Z","timestamp":1403140306000},"page":"749-756","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1145,"title":["Lifetime Prevalence of Congenital Heart Disease in the General Population From 2000 to 2010"],"prefix":"10.1161","volume":"130","author":[{"given":"Ariane J.","family":"Marelli","sequence":"first","affiliation":[{"name":"From the McGill Adult Unit for Congenital Heart Disease Excellence (A.J.M., R.I.-I., L.G., M.K.) and Division of Clinical Epidemiology (N.D.), McGill University Health Centre, Montreal, Canada; and Division of Cardiology, Stollery Children\u2019s Hospital and Department of Pediatrics, University of Alberta, Edmonton, Canada (A.S.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raluca","family":"Ionescu-Ittu","sequence":"additional","affiliation":[{"name":"From the McGill Adult Unit for Congenital Heart Disease Excellence (A.J.M., R.I.-I., L.G., M.K.) and Division of Clinical Epidemiology (N.D.), McGill University Health Centre, Montreal, Canada; and Division of Cardiology, Stollery Children\u2019s Hospital and Department of Pediatrics, University of Alberta, Edmonton, Canada (A.S.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew S.","family":"Mackie","sequence":"additional","affiliation":[{"name":"From the McGill Adult Unit for Congenital Heart Disease Excellence (A.J.M., R.I.-I., L.G., M.K.) and Division of Clinical Epidemiology (N.D.), McGill University Health Centre, Montreal, Canada; and Division of Cardiology, Stollery Children\u2019s Hospital and Department of Pediatrics, University of Alberta, Edmonton, Canada (A.S.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liming","family":"Guo","sequence":"additional","affiliation":[{"name":"From the McGill Adult Unit for Congenital Heart Disease Excellence (A.J.M., R.I.-I., L.G., M.K.) and Division of Clinical Epidemiology (N.D.), McGill University Health Centre, Montreal, Canada; and Division of Cardiology, Stollery Children\u2019s Hospital and Department of Pediatrics, University of Alberta, Edmonton, Canada (A.S.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nandini","family":"Dendukuri","sequence":"additional","affiliation":[{"name":"From the McGill Adult Unit for Congenital Heart Disease Excellence (A.J.M., R.I.-I., L.G., M.K.) and Division of Clinical Epidemiology (N.D.), McGill University Health Centre, Montreal, Canada; and Division of Cardiology, Stollery Children\u2019s Hospital and Department of Pediatrics, University of Alberta, Edmonton, Canada (A.S.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Kaouache","sequence":"additional","affiliation":[{"name":"From the McGill Adult Unit for Congenital Heart Disease Excellence (A.J.M., R.I.-I., L.G., M.K.) and Division of Clinical Epidemiology (N.D.), McGill University Health Centre, Montreal, Canada; and Division of Cardiology, Stollery Children\u2019s Hospital and Department of Pediatrics, University of Alberta, Edmonton, Canada (A.S.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2008.05.059"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e31823ac046"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.106.627224"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.03.085"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.108.190690"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2012-3435"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.109.866319"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.03.033"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2010.07.017"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2007.11.003"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.108.839464"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2006.10.054"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.06.041"},{"key":"e_1_3_3_15_2","unstructured":"Russo CA Elixhauser A. Hospitalizations for Birth Defects 2004. HCUP Statistical Brief #24. Rockville MD: Agency for Healthcare Research and Quality; January 2007. http:\/\/www.hcup-us.ahrq.gov\/reports\/statbriefs\/sb24.pdf. Accessed June 5 2014."},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2008.08.029"},{"key":"e_1_3_3_17_2","volume-title":"Annual Demographic Statistics","author":"Statistics Canada","year":"2010","unstructured":"Statistics Canada. Table 051-0001: estimates of population, by age group and sex for July 1, Canada, provinces and territories, annual (persons unless otherwise noted). Annual Demographic Statistics. CANSIM (database). 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Report of the New England Regional Infant Cardiac Program. Pediatrics. 1980;65:375\u2013461.","journal-title":"Pediatrics"},{"key":"e_1_3_3_30_2","unstructured":"Institut de la statistique Qu\u00e9bec. Donn\u00e9es d\u00e9mographiques r\u00e9gionales: estimation de la popultaion des r\u00e9gions m\u00e9tropolitaines de recensement selon le groupe d\u2019\u00e2ge et le sexe. Institut de la Statistique Qu\u00e9bec Web site. 2013. http:\/\/www.stat.gouv.qc.ca\/donstat\/societe\/demographie\/dons_regnl\/regional\/indei.htm. Accessed May 1 2014."}],"container-title":["Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCULATIONAHA.113.008396","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T03:13:12Z","timestamp":1715569992000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCULATIONAHA.113.008396"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8,26]]},"references-count":29,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2014,8,26]]}},"alternative-id":["10.1161\/CIRCULATIONAHA.113.008396"],"URL":"https:\/\/doi.org\/10.1161\/circulationaha.113.008396","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.718457354.793532719","asserted-by":"object"}]},"ISSN":["0009-7322","1524-4539"],"issn-type":[{"value":"0009-7322","type":"print"},{"value":"1524-4539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,8,26]]},"assertion":[{"value":"2013-12-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-06-06","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-06-18","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}