{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T12:40:49Z","timestamp":1792240849860,"version":"4.4.0"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"24","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:sec>\n                    <jats:title>Background\u2014<\/jats:title>\n                    <jats:p>Mycotic aortic aneurysm (MAA) is a rare and life-threatening disease. The aim of this European multicenter collaboration was to study the durability of endovascular aortic repair (EVAR) of MAA, by assessing late infection\u2013related complications and long-term survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results\u2014<\/jats:title>\n                    <jats:p>All EVAR treated MAAs, between 1999 and 2013 at 16 European centers, were retrospectively reviewed. One hundred twenty-three patients with 130 MAAs were identified. Mean age was 69 years (range 39\u201386), 87 (71%) were men, 58 (47%) had immunodeficiency, and 47 (38%) presented with rupture. Anatomic locations were ascending\/arch (n=4), descending (n=34), paravisceral (n=15), infrarenal aorta (n=63), and multiple (n=7). Treatments were thoracic EVAR (n=43), fenestrated\/branched EVAR (n=9), and infrarenal EVAR (n=71). Antibiotic was administered for mean 30 weeks. Mean follow-up was 35 months (range 1 week to 149 months). Six patients (5%) were converted to open repair during follow-up. Survival was 91% (95% confidence interval, 86% to 96%), 75% (67% to 83%), 55% (44% to 66%), and 41% (28% to 54%) after 1, 12, 60, and 120 months, respectively. Infection-related death occurred in 23 patients (19%), 9 after discontinuation of antibiotic treatment. A Cox regression analysis demonstrated non-Salmonella\u2013positive culture as predictors for late infection\u2013related death.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions\u2014<\/jats:title>\n                    <jats:p>Endovascular treatment of MAA is feasible and for most patients a durable treatment option. Late infections do occur, are often lethal, and warrant long-term antibiotic treatment and follow-up. Patients with non-Salmonella\u2013positive blood cultures were more likely to die from late infection.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/circulationaha.114.009481","type":"journal-article","created":{"date-parts":[[2014,11,7]],"date-time":"2014-11-07T03:40:46Z","timestamp":1415331646000},"page":"2136-2142","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":260,"title":["Endovascular Treatment of Mycotic Aortic Aneurysms"],"prefix":"10.1161","volume":"130","author":[{"given":"Karl","family":"S\u00f6relius","sequence":"first","affiliation":[{"name":"From the Institution of Surgical Sciences, Department of Vascular Surgery, Uppsala University, Sweden (K.S., K.M., M.B., A.W.); Department of Vascular Surgery, Na Homolce Hospital, Prague, Czech Republic (P.S.); Department of Vascular Surgery, Karolinska Hospital, Stockholm, Sweden (C.-M.W.); Department of Vascular Surgery, Guy\u2019s &amp; St. Thomas\u2019 Hospital, London, United Kingdom (R.E.C., P.T., O.L.); St. George\u2019s Vascular Institute, London, United Kingdom (M.T., J. Brownrigg); Department of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin","family":"Mani","sequence":"additional","affiliation":[{"name":"From the Institution of Surgical Sciences, Department of Vascular Surgery, Uppsala University, Sweden (K.S., K.M., M.B., A.W.); Department of Vascular Surgery, Na Homolce Hospital, Prague, Czech Republic (P.S.); Department of Vascular Surgery, Karolinska Hospital, Stockholm, Sweden (C.-M.W.); Department of Vascular Surgery, Guy\u2019s &amp; St. Thomas\u2019 Hospital, London, United Kingdom (R.E.C., P.T., O.L.); St. George\u2019s Vascular Institute, London, United Kingdom (M.T., J. Brownrigg); Department of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Bj\u00f6rck","sequence":"additional","affiliation":[{"name":"From the Institution of Surgical Sciences, Department of Vascular Surgery, Uppsala University, Sweden (K.S., K.M., M.B., A.W.); Department of Vascular Surgery, Na Homolce Hospital, Prague, Czech Republic (P.S.); Department of Vascular Surgery, Karolinska Hospital, Stockholm, Sweden (C.-M.W.); Department of Vascular Surgery, Guy\u2019s &amp; St. Thomas\u2019 Hospital, London, United Kingdom (R.E.C., P.T., O.L.); St. George\u2019s Vascular Institute, London, United Kingdom (M.T., J. Brownrigg); Department of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petr","family":"Sedivy","sequence":"additional","affiliation":[{"name":"From the Institution of Surgical Sciences, Department of Vascular Surgery, Uppsala University, Sweden (K.S., K.M., M.B., A.W.); Department of Vascular Surgery, Na Homolce Hospital, Prague, Czech Republic (P.S.); Department of Vascular Surgery, Karolinska Hospital, Stockholm, Sweden (C.-M.W.); Department of Vascular Surgery, Guy\u2019s &amp; St. Thomas\u2019 Hospital, London, United Kingdom (R.E.C., P.T., O.L.); St. George\u2019s Vascular Institute, London, United Kingdom (M.T., J. Brownrigg); Department of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl-Magnus","family":"Wahlgren","sequence":"additional","affiliation":[{"name":"From the Institution of Surgical Sciences, Department of Vascular Surgery, Uppsala University, Sweden (K.S., K.M., M.B., A.W.); Department of Vascular Surgery, Na Homolce Hospital, Prague, Czech Republic (P.S.); Department of Vascular Surgery, Karolinska Hospital, Stockholm, Sweden (C.-M.W.); Department of Vascular Surgery, Guy\u2019s &amp; St. Thomas\u2019 Hospital, London, United Kingdom (R.E.C., P.T., O.L.); St. George\u2019s Vascular Institute, London, United Kingdom (M.T., J. Brownrigg); Department of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Taylor","sequence":"additional","affiliation":[{"name":"From the Institution of Surgical Sciences, Department of Vascular Surgery, Uppsala University, Sweden (K.S., K.M., M.B., A.W.); Department of Vascular Surgery, Na Homolce Hospital, Prague, Czech Republic (P.S.); Department of Vascular Surgery, Karolinska Hospital, Stockholm, Sweden (C.-M.W.); Department of Vascular Surgery, Guy\u2019s &amp; St. Thomas\u2019 Hospital, London, United Kingdom (R.E.C., P.T., O.L.); St. George\u2019s Vascular Institute, London, United Kingdom (M.T., J. Brownrigg); Department of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rachel E.","family":"Clough","sequence":"additional","affiliation":[{"name":"From the Institution of Surgical Sciences, Department of Vascular Surgery, Uppsala University, Sweden (K.S., K.M., M.B., A.W.); Department of Vascular Surgery, Na Homolce Hospital, Prague, Czech Republic (P.S.); Department of Vascular Surgery, Karolinska Hospital, Stockholm, Sweden (C.-M.W.); Department of Vascular Surgery, Guy\u2019s &amp; St. Thomas\u2019 Hospital, London, United Kingdom (R.E.C., P.T., O.L.); St. George\u2019s Vascular Institute, London, United Kingdom (M.T., J. 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Brownrigg); Department of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matt","family":"Thompson","sequence":"additional","affiliation":[{"name":"From the Institution of Surgical Sciences, Department of Vascular Surgery, Uppsala University, Sweden (K.S., K.M., M.B., A.W.); Department of Vascular Surgery, Na Homolce Hospital, Prague, Czech Republic (P.S.); Department of Vascular Surgery, Karolinska Hospital, Stockholm, Sweden (C.-M.W.); Department of Vascular Surgery, Guy\u2019s &amp; St. Thomas\u2019 Hospital, London, United Kingdom (R.E.C., P.T., O.L.); St. George\u2019s Vascular Institute, London, United Kingdom (M.T., J. 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Brownrigg); Department of..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Usman","family":"Jaffer","sequence":"additional","affiliation":[{"name":"From the Institution of Surgical Sciences, Department of Vascular Surgery, Uppsala University, Sweden (K.S., K.M., M.B., A.W.); Department of Vascular Surgery, Na Homolce Hospital, Prague, Czech Republic (P.S.); Department of Vascular Surgery, Karolinska Hospital, Stockholm, Sweden (C.-M.W.); Department of Vascular Surgery, Guy\u2019s &amp; St. Thomas\u2019 Hospital, London, United Kingdom (R.E.C., P.T., O.L.); St. George\u2019s Vascular Institute, London, United Kingdom (M.T., J. 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