{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T23:16:43Z","timestamp":1792192603513,"version":"4.4.0"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"18","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[2015,5,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background\u2014<\/jats:title>\n                    <jats:p>We aimed to determine the incidence, predictors, clinical characteristics, management, and outcomes of infective endocarditis (IE) after transcatheter aortic valve implantation (TAVI).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and Results\u2014<\/jats:title>\n                    <jats:p>\n                      This multicenter registry included 53 patients (mean age, 79\u00b18 years; men, 57%) who suffered IE after TAVI of 7944 patients after a mean follow-up of 1.1\u00b11.2 years (incidence, 0.67%, 0.50% within the first year after TAVI). Mean time from TAVI was 6 months (interquartile range, 1\u201314 months). Orotracheal intubation (hazard ratio, 3.87; 95% confidence interval, 1.55\u20139.64;\n                      <jats:italic>P<\/jats:italic>\n                      =0.004) and the self-expandable CoreValve system (hazard ratio, 3.12; 95% confidence interval, 1.37\u20137.14;\n                      <jats:italic>P<\/jats:italic>\n                      =0.007) were associated with IE (multivariate analysis including 3067 patients with individual data). The most frequent causal microorganisms were\n                      <jats:italic>coagulase-negative staphylococci<\/jats:italic>\n                      (24%), followed by\n                      <jats:italic>Staphylococcus aureus<\/jats:italic>\n                      (21%) and\n                      <jats:italic>enterococci<\/jats:italic>\n                      (21%). Vegetations were present in 77% of patients (transcatheter valve leaflets, 39%; stent frame, 17%; mitral valve, 21%). At least 1 complication of IE occurred in 87% of patients (heart failure in 68%). However, only 11% of patients underwent valve intervention (valve explantation and valve-in-valve procedure in 4 and 2 patients, respectively). The mortality rate in hospital was 47.2% and increased to 66% at the 1-year follow-up. IE complications such as heart failure (\n                      <jats:italic>P<\/jats:italic>\n                      =0.037) and septic shock (\n                      <jats:italic>P<\/jats:italic>\n                      =0.002) were associated with increased in-hospital mortality.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions\u2014<\/jats:title>\n                    <jats:p>\n                      The incidence of IE at 1 year after TAVI was 0.50%, and the risk increased with the use of orotracheal intubation and a self-expandable valve system.\n                      <jats:italic>Staphylococci<\/jats:italic>\n                      and\n                      <jats:italic>enterococci<\/jats:italic>\n                      were the most common agents. Although most patients presented at least 1 complication of IE, valve intervention was performed in a minority of patients, and nearly half of the patients died during the hospitalization period.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/circulationaha.114.014089","type":"journal-article","created":{"date-parts":[[2015,3,9]],"date-time":"2015-03-09T22:12:59Z","timestamp":1425939179000},"page":"1566-1574","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":254,"title":["Infective Endocarditis After Transcatheter Aortic Valve Implantation"],"prefix":"10.1161","volume":"131","author":[{"given":"Ignacio J.","family":"Amat-Santos","sequence":"first","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Messika-Zeitoun","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helene","family":"Eltchaninoff","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samir","family":"Kapadia","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stamatios","family":"Lerakis","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asim N.","family":"Cheema","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrique","family":"Guti\u00e9rrez-Ibanes","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio J.","family":"Munoz-Garcia","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manuel","family":"Pan","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John G.","family":"Webb","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard C.","family":"Herrmann","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Susheel","family":"Kodali","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Nombela-Franco","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corrado","family":"Tamburino","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hasan","family":"Jilaihawi","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Bernard","family":"Masson","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Fabio Sandoli","family":"de Brito","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Cristina","family":"Ferreira","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valter Correa","family":"Lima","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Armando","family":"Mangione","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernard","family":"Iung","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alec","family":"Vahanian","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Durand","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. Murat","family":"Tuzcu","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salim S.","family":"Hayek","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rocio","family":"Angulo-Llanos","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan J.","family":"G\u00f3mez-Doblas","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. 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Kapadia, E.M.T.); Emory University School of Medicine, Division of Cardiology, Atlanta, GA (S.L., S.S.H.);..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danny","family":"Dvir","sequence":"additional","affiliation":[{"name":"From Quebec Heart &amp; Lung Institute, Quebec, Canada (I.J.A.-S., H.B.R., M.U., E.D., P.P., J.R.-C.); Hospital Cl\u00ednico Universitario de Valladolid, Spain (I.J.A.-S., J.L, A.S.R.); Assistance Publique-H\u00f4pitaux de Paris, Bichat Hospital, France (D.M.-Z., B.I., A.V.); H\u00f4pital Charles Nicolle, University of Rouen, France (H.E., E.D.); Department of Cardiovascular Medicine, Cleveland Clinic, OH (S. 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