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Management of peripartum cardiomyopathy is largely limited to the same neurohormonal antagonists used in other forms of cardiomyopathy, and no proven disease-specific therapies exist yet. Research in the past decade has suggested that peripartum cardiomyopathy is caused by vascular dysfunction, triggered by late-gestational maternal hormones. Most recently, information has also indicated that many cases of peripartum cardiomyopathy have genetic underpinnings. We review here the known epidemiology, clinical presentation, and management of peripartum cardiomyopathy, as well as the current knowledge of the pathophysiology of the disease.<\/jats:p>","DOI":"10.1161\/circulationaha.115.020491","type":"journal-article","created":{"date-parts":[[2016,4,4]],"date-time":"2016-04-04T18:04:21Z","timestamp":1459793061000},"page":"1397-1409","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":368,"title":["Peripartum Cardiomyopathy"],"prefix":"10.1161","volume":"133","author":[{"given":"Zolt","family":"Arany","sequence":"first","affiliation":[{"name":"From Perelman School of Medicine, University of Pennsylvania, Philadelphia (Z.A.); and Department of Medicine, Division of Cardiovascular Medicine and Department of Obstetrics and Gynecology, University of Southern California, Los Angeles (U.E.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uri","family":"Elkayam","sequence":"additional","affiliation":[{"name":"From Perelman School of Medicine, University of Pennsylvania, Philadelphia (Z.A.); and Department of Medicine, Division of Cardiovascular Medicine and Department of Obstetrics and Gynecology, University of Southern California, Los Angeles (U.E.)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","volume-title":"De L\u2019influence reciproque de la grossesse et del maladies du Coeur [thesis]","author":"Porak C","year":"1880","unstructured":"Porak C. 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