{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,13]],"date-time":"2025-11-13T07:08:14Z","timestamp":1763017694649},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[2017,1,3]]},"abstract":"<jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Guidelines recommend that patients with low ejection fraction (EF) after myocardial infarction (MI) have their EF reassessed 40 days after MI for implantable cardioverter-defibrillator (ICD) candidacy. This study examines rates of EF reassessment and their association with 1-year ICD implantation in post-MI patients with low EF.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>\n              We examined rates of postdischarge EF reassessment and ICD implantation among 10\u2009289 Medicare-insured patients \u226565 years of age with an EF\u226435% during the index MI admission from January 2007 through September 2010 in ACTION Registry\u2013GWTG (Acute Coronary Treatment and Intervention Outcomes Network Registry\n              <jats:sup>\u2013<\/jats:sup>\n              Get With The Guidelines). Multivariable Cox models tested the association between time-dependent EF reassessment and 1-year ICD implantation, stratified by revascularization status during the index MI admission.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>\n              Among patients with EF \u226435% during the index MI admission, 66.8% (95% confidence interval [CI], 65.9\u201367.8) had EF reassessment within the next year. Revascularized patients were more likely to have EF reassessment (76.9% [95% CI, 75.8\u201378.0)] versus 53.7% [95% CI, 52.2\u201355.2];\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001) and had shorter times to EF reassessment (median, 67 versus 84 days;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001) than nonrevascularized patients. Among patients with EF reassessment, only 11% received an ICD within 1 year. Reassessment of EF was associated with a higher likelihood of ICD implantation for both revascularized (unadjusted, 12.1% versus 2.4%,\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001; adjusted hazard ratio, 10.6, 95% CI, 7.7\u201314.8) and nonrevascularized (unadjusted, 10.0% versus 1.7%,\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001; adjusted hazard ratio, 6.1, 95% CI, 4.1\u20139.2) patients.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>In US practice, EF reassessments are commonly performed among patients with MI with an initially reduced EF. Although 1-year EF reassessment is associated with increased likelihood of ICD implantation, 1-year ICD implantation rates remain very low even among patients with EF reassessment, regardless of revascularization status.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/circulationaha.116.022359","type":"journal-article","created":{"date-parts":[[2016,11,18]],"date-time":"2016-11-18T01:10:27Z","timestamp":1479431427000},"page":"38-47","update-policy":"http:\/\/dx.doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":14,"title":["Reassessment of Cardiac Function and Implantable Cardioverter-Defibrillator Use Among Medicare Patients With Low Ejection Fraction After Myocardial Infarction"],"prefix":"10.1161","volume":"135","author":[{"given":"Sean D.","family":"Pokorney","sequence":"first","affiliation":[{"name":"From Duke University Medical Center, Durham, NC (S.D.P., S.M.A.-K., E.J.V., E.D.P., T.Y.W.); Duke Clinical Research Institute, Durham, NC (S.D.P., A.Y.C., L.T., S.M.A.-K., E.J.V., E.D.P., T.Y.W.); Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA (A.L.M.); UCLA Health System, Los Angeles, CA (G.C.F.); and UT Southwestern Medical Center, Dallas, TX (J.A.d.L.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy L.","family":"Miller","sequence":"additional","affiliation":[{"name":"From Duke University Medical Center, Durham, NC (S.D.P., S.M.A.-K., E.J.V., E.D.P., T.Y.W.); Duke Clinical Research Institute, Durham, NC (S.D.P., A.Y.C., L.T., S.M.A.-K., E.J.V., E.D.P., T.Y.W.); Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA (A.L.M.); UCLA Health System, Los Angeles, CA (G.C.F.); and UT Southwestern Medical Center, Dallas, TX (J.A.d.L.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anita Y.","family":"Chen","sequence":"additional","affiliation":[{"name":"From Duke University Medical Center, Durham, NC (S.D.P., S.M.A.-K., E.J.V., E.D.P., T.Y.W.); Duke Clinical Research Institute, Durham, NC (S.D.P., A.Y.C., L.T., S.M.A.-K., E.J.V., E.D.P., T.Y.W.); Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA (A.L.M.); UCLA Health System, Los Angeles, CA (G.C.F.); and UT Southwestern Medical Center, Dallas, TX (J.A.d.L.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laine","family":"Thomas","sequence":"additional","affiliation":[{"name":"From Duke University Medical Center, Durham, NC (S.D.P., S.M.A.-K., E.J.V., E.D.P., T.Y.W.); Duke Clinical Research Institute, Durham, NC (S.D.P., A.Y.C., L.T., S.M.A.-K., E.J.V., E.D.P., T.Y.W.); Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA (A.L.M.); UCLA Health System, Los Angeles, CA (G.C.F.); and UT Southwestern Medical Center, Dallas, TX (J.A.d.L.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregg C.","family":"Fonarow","sequence":"additional","affiliation":[{"name":"From Duke University Medical Center, Durham, NC (S.D.P., S.M.A.-K., E.J.V., E.D.P., T.Y.W.); Duke Clinical Research Institute, Durham, NC (S.D.P., A.Y.C., L.T., S.M.A.-K., E.J.V., E.D.P., T.Y.W.); Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA (A.L.M.); UCLA Health System, Los Angeles, CA (G.C.F.); and UT Southwestern Medical Center, Dallas, TX (J.A.d.L.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James A.","family":"de Lemos","sequence":"additional","affiliation":[{"name":"From Duke University Medical Center, Durham, NC (S.D.P., S.M.A.-K., E.J.V., E.D.P., T.Y.W.); Duke Clinical Research Institute, Durham, NC (S.D.P., A.Y.C., L.T., S.M.A.-K., E.J.V., E.D.P., T.Y.W.); Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA (A.L.M.); UCLA Health System, Los Angeles, CA (G.C.F.); and UT Southwestern Medical Center, Dallas, TX (J.A.d.L.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sana M.","family":"Al-Khatib","sequence":"additional","affiliation":[{"name":"From Duke University Medical Center, Durham, NC (S.D.P., S.M.A.-K., E.J.V., E.D.P., T.Y.W.); Duke Clinical Research Institute, Durham, NC (S.D.P., A.Y.C., L.T., S.M.A.-K., E.J.V., E.D.P., T.Y.W.); Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA (A.L.M.); UCLA Health System, Los Angeles, CA (G.C.F.); and UT Southwestern Medical Center, Dallas, TX (J.A.d.L.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric J.","family":"Velazquez","sequence":"additional","affiliation":[{"name":"From Duke University Medical Center, Durham, NC (S.D.P., S.M.A.-K., E.J.V., E.D.P., T.Y.W.); Duke Clinical Research Institute, Durham, NC (S.D.P., A.Y.C., L.T., S.M.A.-K., E.J.V., E.D.P., T.Y.W.); Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA (A.L.M.); UCLA Health System, Los Angeles, CA (G.C.F.); and UT Southwestern Medical Center, Dallas, TX (J.A.d.L.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric D.","family":"Peterson","sequence":"additional","affiliation":[{"name":"From Duke University Medical Center, Durham, NC (S.D.P., S.M.A.-K., E.J.V., E.D.P., T.Y.W.); Duke Clinical Research Institute, Durham, NC (S.D.P., A.Y.C., L.T., S.M.A.-K., E.J.V., E.D.P., T.Y.W.); Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA (A.L.M.); UCLA Health System, Los Angeles, CA (G.C.F.); and UT Southwestern Medical Center, Dallas, TX (J.A.d.L.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tracy Y.","family":"Wang","sequence":"additional","affiliation":[{"name":"From Duke University Medical Center, Durham, NC (S.D.P., S.M.A.-K., E.J.V., E.D.P., T.Y.W.); Duke Clinical Research Institute, Durham, NC (S.D.P., A.Y.C., L.T., S.M.A.-K., E.J.V., E.D.P., T.Y.W.); Brigham and Women\u2019s Hospital and Harvard Medical School, Boston, MA (A.L.M.); UCLA Health System, Los Angeles, CA (G.C.F.); and UT Southwestern Medical Center, Dallas, TX (J.A.d.L.)."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa013474"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa043399"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa043938"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa041489"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0901889"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/0735-1097(95)00012-S"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.96.10.3294"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa010713"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)01965-4"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(99)00157-6"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-134-6-200103200-00009"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCUALTIONAHA.108.189742"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e31829e8807"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.12.026"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.002539"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2013.07.019"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.6409"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.27.5.1315"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.297.8.831"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1161\/circoutcomes.108.847145"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2010.200261"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2009.04.002"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1214\/aos\/1176350951"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2005.08.021"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.12218"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.009924"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.508093"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.115.017001"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.115.002291"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2013.01.008"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.114.001306"}],"container-title":["Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCULATIONAHA.116.022359","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T06:34:31Z","timestamp":1715582071000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCULATIONAHA.116.022359"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,1,3]]},"references-count":31,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1,3]]}},"alternative-id":["10.1161\/CIRCULATIONAHA.116.022359"],"URL":"https:\/\/doi.org\/10.1161\/circulationaha.116.022359","relation":{},"ISSN":["0009-7322","1524-4539"],"issn-type":[{"value":"0009-7322","type":"print"},{"value":"1524-4539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,1,3]]},"assertion":[{"value":"2016-03-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-10-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-11-16","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}