{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T18:15:28Z","timestamp":1792001728498,"version":"4.4.0"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[2017,2,28]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Small studies have suggested that high-intensity interval training (HIIT) is superior to moderate continuous training (MCT) in reversing cardiac remodeling and increasing aerobic capacity in patients with heart failure with reduced ejection fraction. The present multicenter trial compared 12 weeks of supervised interventions of HIIT, MCT, or a recommendation of regular exercise (RRE).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Two hundred sixty-one patients with left ventricular ejection fraction \u226435% and New York Heart Association class II to III were randomly assigned to HIIT at 90% to 95% of maximal heart rate, MCT at 60% to 70% of maximal heart rate, or RRE. Thereafter, patients were encouraged to continue exercising on their own. Clinical assessments were performed at baseline, after the intervention, and at follow-up after 52 weeks. Primary end point was a between-group comparison of change in left ventricular end-diastolic diameter from baseline to 12 weeks.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Groups did not differ in age (median, 60 years), sex (19% women), ischemic pathogenesis (59%), or medication. Change in left ventricular end-diastolic diameter from baseline to 12 weeks was not different between HIIT and MCT (\n                      <jats:italic>P<\/jats:italic>\n                      =0.45); left ventricular end-diastolic diameter changes compared with RRE were \u22122.8 mm (\u22125.2 to \u22120.4 mm;\n                      <jats:italic>P<\/jats:italic>\n                      =0.02) in HIIT and \u22121.2 mm (\u22123.6 to 1.2 mm;\n                      <jats:italic>P<\/jats:italic>\n                      =0.34) in MCT. There was also no difference between HIIT and MCT in peak oxygen uptake (\n                      <jats:italic>P<\/jats:italic>\n                      =0.70), but both were superior to RRE. However, none of these changes was maintained at follow-up after 52 weeks. Serious adverse events were not statistically different during supervised intervention or at follow-up at 52 weeks (HIIT, 39%; MCT, 25%; RRE, 34%;\n                      <jats:italic>P<\/jats:italic>\n                      =0.16). Training records showed that 51% of patients exercised below prescribed target during supervised HIIT and 80% above target in MCT.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>HIIT was not superior to MCT in changing left ventricular remodeling or aerobic capacity, and its feasibility remains unresolved in patients with heart failure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Clinical Trial Registration:<\/jats:title>\n                    <jats:p>\n                      URL:\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"http:\/\/www.clinicaltrials.gov\">http:\/\/www.clinicaltrials.gov<\/jats:ext-link>\n                      . Unique identifier: NCT00917046.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/circulationaha.116.022924","type":"journal-article","created":{"date-parts":[[2017,1,12]],"date-time":"2017-01-12T21:30:44Z","timestamp":1484256644000},"page":"839-849","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":375,"title":["High-Intensity Interval Training in Patients With Heart Failure With Reduced Ejection Fraction"],"prefix":"10.1161","volume":"135","author":[{"given":"\u00d8yvind","family":"Ellingsen","sequence":"first","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Halle","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viviane","family":"Conraads","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asbj\u00f8rn","family":"St\u00f8ylen","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H\u00e5vard","family":"Dalen","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles","family":"Delagardelle","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alf-Inge","family":"Larsen","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torstein","family":"Hole","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alessandro","family":"Mezzani","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emeline M.","family":"Van Craenenbroeck","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vibeke","family":"Videm","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Beckers","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey W.","family":"Christle","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ephraim","family":"Winzer","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norman","family":"Mangner","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix","family":"Woitek","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"H\u00f6llriegel","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel","family":"Pressler","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tea","family":"Monk-Hansen","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Snoer","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Feiereisen","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Torstein","family":"Valborgland","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Kjekshus","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rainer","family":"Hambrecht","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Gielen","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trine","family":"Karlsen","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Prescott","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Axel","family":"Linke","sequence":"additional","affiliation":[{"name":"From St. Olavs Hospital, Trondheim University Hospital, Norway (\u00d8.E., A.S., H.D., V.V., T.K.); K.G. Jebsen Center for Exercise in Medicine, Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway (\u00d8.E., H.D., T.K.); Department of Prevention, Rehabilitation and Sports Medicine, Technische Universit\u00e4t M\u00fcnchen, Klinikum rechts der Isar, Germany (M.H., J.W.C., A.P.); DZHK (German Center for Cardiovascular Research), Partner Site Munich Heart..."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehw128"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/2047487312437063"},{"key":"e_1_3_4_4_2","first-page":"CD003331","article-title":"Exercise-based rehabilitation for heart failure.","volume":"4","author":"Taylor RS","year":"2014","unstructured":"Taylor RS, Sagar VA, Davies EJ, Briscoe S, Coats AJ, Dalal H, Lough F, Rees K, Singh S. Exercise-based rehabilitation for heart failure. Cochrane Database Syst Rev. 2014;4:CD003331.","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.454"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.675041"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000081780.38477.FA"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.02.055"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1177\/1741826711403252"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.hjr.0000131677.96762.0c"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/ejechocard\/jep188"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2003.08.009"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2013.01.303"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2014.10.155"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.123117"}],"container-title":["Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCULATIONAHA.116.022924","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T03:15:40Z","timestamp":1715570140000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCULATIONAHA.116.022924"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,2,28]]},"references-count":14,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2017,2,28]]}},"alternative-id":["10.1161\/CIRCULATIONAHA.116.022924"],"URL":"https:\/\/doi.org\/10.1161\/circulationaha.116.022924","relation":{},"ISSN":["0009-7322","1524-4539"],"issn-type":[{"value":"0009-7322","type":"print"},{"value":"1524-4539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,2,28]]},"assertion":[{"value":"2016-04-09","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-12-15","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-01-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}