{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,5,14]],"date-time":"2024-05-14T00:15:31Z","timestamp":1715645731392},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"23","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[2019,12,3]]},"DOI":"10.1161\/circulationaha.119.043935","type":"journal-article","created":{"date-parts":[[2019,12,2]],"date-time":"2019-12-02T19:00:28Z","timestamp":1575313228000},"page":"1860-1864","update-policy":"http:\/\/dx.doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":1,"title":["Balanced Dysfunction in the Healthcare Ecosystem Harms Patients"],"prefix":"10.1161","volume":"140","author":[{"given":"Robert M.","family":"Califf","sequence":"first","affiliation":[{"name":"Duke Forge, Duke University School of Medicine, Durham, NC. Department of Medicine, Stanford University School of Medicine, CA. Verily Life Sciences, South San Francisco, CA."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.7326\/M17-2441"},{"key":"e_1_3_2_3_2","volume-title":"Health, United States, 2017: With Special Feature on Mortality","year":"2018","unstructured":"Health, United States, 2017: With Special Feature on Mortality. Hyattsville, MD: National Center for Health Statistics; 2018."},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehv641"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1410489"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehx450"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1615664"},{"key":"e_1_3_2_8_2","volume-title":"Paper presented at: American College of Cardiology 67th Scientific Sessions;","author":"Schwartz GG","year":"2018","unstructured":"Schwartz, GG, Szarek, M, Bhatt, DL, Bittner, V, Diaz, R, Edelberg, J, Goodman, SG, et al. The ODYSSEY OUTCOMES Trial: alirocumab in patients after acute coronary syndrome. Paper presented at: American College of Cardiology 67th Scientific Sessions; March 10, 2018; Orlando, FL."},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2017.10.001"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.11004"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40273-018-0671-0"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.13985"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2017.3451"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.5607"},{"key":"e_1_3_2_15_2","article-title":"These cholesterol-reducers may save lives: so why aren\u2019t heart patients getting them?","author":"Kolata G","year":"2018","unstructured":"Kolata, G. These cholesterol-reducers may save lives: so why aren\u2019t heart patients getting them? The New York Times. October 2, 2018.","journal-title":"The New York Times"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.118.005404"},{"key":"e_1_3_2_17_2","article-title":"Amgen announces 60% reduction in list price of PCSK9 inhibitor evolocumab.","author":"Dangi-Garimella S","year":"2018","unstructured":"Dangi-Garimella, S. Amgen announces 60% reduction in list price of PCSK9 inhibitor evolocumab. Am J Manag Care. October 24, 2018. https:\/\/www.ajmc.com\/newsroom\/amgen-announces-60-reduction-in-list-price-of-pcsk9-inhibitor-evolocumab. Accessed September 9, 2019.","journal-title":"Am J Manag Care"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000625"},{"key":"e_1_3_2_19_2","volume-title":"Paper presented at: European Society of Cardiology Congress 2019","author":"Ray KK","unstructured":"Ray, KK. Impact of inclisiran on LDL-C over 18 months in patients with ASCVD or risk-equivalent: results of the phase 3 ORION-11 trial. Paper presented at: European Society of Cardiology Congress 2019; September 2, 2019; Paris, France."}],"container-title":["Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCULATIONAHA.119.043935","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T07:49:18Z","timestamp":1715586558000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCULATIONAHA.119.043935"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12,3]]},"references-count":18,"journal-issue":{"issue":"23","published-print":{"date-parts":[[2019,12,3]]}},"alternative-id":["10.1161\/CIRCULATIONAHA.119.043935"],"URL":"https:\/\/doi.org\/10.1161\/circulationaha.119.043935","relation":{},"ISSN":["0009-7322","1524-4539"],"issn-type":[{"value":"0009-7322","type":"print"},{"value":"1524-4539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,12,3]]},"assertion":[{"value":"2019-12-02","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}