{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,20]],"date-time":"2026-02-20T21:43:40Z","timestamp":1771623820205,"version":"3.50.1"},"reference-count":5,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[2024,9,3]]},"DOI":"10.1161\/circulationaha.122.061322","type":"journal-article","created":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T18:00:57Z","timestamp":1725386457000},"page":"816-820","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Angiotensin-(1-9) Retro-Enantiomer Peptide With Cardioprotective Activity"],"prefix":"10.1161","volume":"150","author":[{"given":"Yvo","family":"Flores","sequence":"first","affiliation":[{"name":"Advanced Center for Chronic Diseases (ACCDiS), Facultad Ciencias Qu\u00edmicas y Farmac\u00e9uticas & Facultad Medicina (Y.F., G.Z.-T., A.N., L.A., C.H.-F., Z.P., M.C., M.J.K., S.L.), Centro de Modelamiento Molecular, Biof\u00edsica y Bioinform\u00e1tica (CM2B2)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gerald","family":"Zapata-Torres","sequence":"additional","affiliation":[{"name":"Advanced Center for Chronic Diseases (ACCDiS), Facultad Ciencias Qu\u00edmicas y Farmac\u00e9uticas & Facultad Medicina (Y.F., G.Z.-T., A.N., L.A., C.H.-F., Z.P., M.C., M.J.K., S.L.), Centro de Modelamiento Molecular, Biof\u00edsica y Bioinform\u00e1tica (CM2B2)."},{"name":"Facultad Ciencias Qu\u00edmicas y Farmac\u00e9uticas (G.Z.-T., D.J.M.), Universidad de Chile, Santiago."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agust\u00edn","family":"Nu\u00f1ez","sequence":"additional","affiliation":[{"name":"Advanced Center for Chronic Diseases (ACCDiS), Facultad Ciencias Qu\u00edmicas y Farmac\u00e9uticas & Facultad Medicina (Y.F., G.Z.-T., A.N., L.A., C.H.-F., Z.P., M.C., M.J.K., S.L.), Centro de Modelamiento Molecular, Biof\u00edsica y Bioinform\u00e1tica (CM2B2)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7673-4081","authenticated-orcid":true,"given":"Douglas J.","family":"Matthies","sequence":"additional","affiliation":[{"name":"Facultad Ciencias Qu\u00edmicas y Farmac\u00e9uticas (G.Z.-T., D.J.M.), Universidad de Chile, Santiago."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larissa","family":"Alem\u00e1n","sequence":"additional","affiliation":[{"name":"Advanced Center for Chronic Diseases (ACCDiS), Facultad Ciencias Qu\u00edmicas y Farmac\u00e9uticas & Facultad Medicina (Y.F., G.Z.-T., A.N., L.A., C.H.-F., Z.P., M.C., M.J.K., S.L.), Centro de Modelamiento Molecular, Biof\u00edsica y Bioinform\u00e1tica (CM2B2)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina","family":"Hern\u00e1ndez-Fuentes","sequence":"additional","affiliation":[{"name":"Advanced Center for Chronic Diseases (ACCDiS), Facultad Ciencias Qu\u00edmicas y Farmac\u00e9uticas & Facultad Medicina (Y.F., G.Z.-T., A.N., L.A., C.H.-F., Z.P., M.C., M.J.K., S.L.), Centro de Modelamiento Molecular, Biof\u00edsica y Bioinform\u00e1tica (CM2B2)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gina","family":"S\u00e1nchez","sequence":"additional","affiliation":[{"name":"Instituto de Ciencias Biom\u00e9dicas (ICBM), Facultad Medicina (G.S., Z.P., S.L.), Universidad de Chile, Santiago."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eyleen","family":"Araya","sequence":"additional","affiliation":[{"name":"Departamento de Ciencias Qu\u00edmicas, Facultad de Ciencias Exactas, Universidad Andres Bello, Santiago, Chile (E.A.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fanny","family":"Guzman","sequence":"additional","affiliation":[{"name":"N\u00facleo de Biotecnolog\u00eda de Curauma (NBC), Pontificia Universidad Cat\u00f3lica de Valpara\u00edso, Chile (F.G.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zully","family":"Pedrozo","sequence":"additional","affiliation":[{"name":"Advanced Center for Chronic Diseases (ACCDiS), Facultad Ciencias Qu\u00edmicas y Farmac\u00e9uticas & Facultad Medicina (Y.F., G.Z.-T., A.N., L.A., C.H.-F., Z.P., M.C., M.J.K., S.L.), Centro de Modelamiento Molecular, Biof\u00edsica y Bioinform\u00e1tica (CM2B2)."},{"name":"Instituto de Ciencias Biom\u00e9dicas (ICBM), Facultad Medicina (G.S., Z.P., S.L.), Universidad de Chile, Santiago."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2644-1659","authenticated-orcid":true,"given":"Salvador","family":"Guardiola","sequence":"additional","affiliation":[{"name":"Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Spain (S.G., M.V., E.G.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3179-079X","authenticated-orcid":true,"given":"M\u00f3nica","family":"Varese","sequence":"additional","affiliation":[{"name":"Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Spain (S.G., M.V., E.G.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ernest","family":"Giralt","sequence":"additional","affiliation":[{"name":"Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Spain (S.G., M.V., E.G.)."},{"name":"Department of Inorganic and Organic Chemistry, University of Barcelona, Spain (E.G.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2322-3819","authenticated-orcid":true,"given":"Ivan","family":"Maslov","sequence":"additional","affiliation":[{"name":"Department of Pharmacology (I.M., M.D.B., R.E.W.), Monash University, Clayton, VIC."},{"name":"Cardiovascular Disease Program, Biomedicine Discovery Institute (I.M., M.D.B., R.E.W.), Monash University, Clayton, VIC."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3724-9814","authenticated-orcid":true,"given":"Mark","family":"Del Borgo","sequence":"additional","affiliation":[{"name":"Department of Pharmacology (I.M., M.D.B., R.E.W.), Monash University, Clayton, VIC."},{"name":"Cardiovascular Disease Program, Biomedicine Discovery Institute (I.M., M.D.B., R.E.W.), Monash University, Clayton, VIC."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6515-0435","authenticated-orcid":true,"given":"Robert E.","family":"Widdop","sequence":"additional","affiliation":[{"name":"Department of Pharmacology (I.M., M.D.B., R.E.W.), Monash University, Clayton, VIC."},{"name":"Cardiovascular Disease Program, Biomedicine Discovery Institute (I.M., M.D.B., R.E.W.), Monash University, Clayton, VIC."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6318-632X","authenticated-orcid":true,"given":"Silvana","family":"Valdebenito","sequence":"additional","affiliation":[{"name":"Australia. Department of Neurobiology, University of Texas Medical Branch (UTMB), Galveston (S.V., E.A.E.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2925-4720","authenticated-orcid":true,"given":"Eliseo A.","family":"Eugenin","sequence":"additional","affiliation":[{"name":"Australia. Department of Neurobiology, University of Texas Medical Branch (UTMB), Galveston (S.V., E.A.E.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5174-6545","authenticated-orcid":true,"given":"Mario","family":"Chiong","sequence":"additional","affiliation":[{"name":"Advanced Center for Chronic Diseases (ACCDiS), Facultad Ciencias Qu\u00edmicas y Farmac\u00e9uticas & Facultad Medicina (Y.F., G.Z.-T., A.N., L.A., C.H.-F., Z.P., M.C., M.J.K., S.L.), Centro de Modelamiento Molecular, Biof\u00edsica y Bioinform\u00e1tica (CM2B2)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5379-1614","authenticated-orcid":true,"given":"Joseph A.","family":"Hill","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine (Cardiology Division) (J.A.H., S.L.), University of Texas Southwestern Medical Center, Dallas."},{"name":"Department of Molecular Biology (J.A.H.), University of Texas Southwestern Medical Center, Dallas."},{"name":"Harry S. Moss Heart Center (J.A.H.), University of Texas Southwestern Medical Center, Dallas."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda Paz","family":"Ocaranza","sequence":"additional","affiliation":[{"name":"Advanced Center for Chronic Diseases (ACCDiS), Facultad Medicina, Pontificia Universidad Cat\u00f3lica de Chile, Santiago (M.P.O.)."},{"name":"Center of New Drugs for Hypertension and Heart Failure (CENDHY), Divisi\u00f3n de Enfermedades Cardiovasculares, Pontificia Universidad Cat\u00f3lica de Chile, Universidad de Chile, and Universidad Andr\u00e9s Bello, Santiago (M.P.O.)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcelo J.","family":"Kogan","sequence":"additional","affiliation":[{"name":"Advanced Center for Chronic Diseases (ACCDiS), Facultad Ciencias Qu\u00edmicas y Farmac\u00e9uticas & Facultad Medicina (Y.F., G.Z.-T., A.N., L.A., C.H.-F., Z.P., M.C., M.J.K., S.L.), Centro de Modelamiento Molecular, Biof\u00edsica y Bioinform\u00e1tica (CM2B2)."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4258-1483","authenticated-orcid":true,"given":"Sergio","family":"Lavandero","sequence":"additional","affiliation":[{"name":"Advanced Center for Chronic Diseases (ACCDiS), Facultad Ciencias Qu\u00edmicas y Farmac\u00e9uticas & Facultad Medicina (Y.F., G.Z.-T., A.N., L.A., C.H.-F., Z.P., M.C., M.J.K., S.L.), Centro de Modelamiento Molecular, Biof\u00edsica y Bioinform\u00e1tica (CM2B2)."},{"name":"Instituto de Ciencias Biom\u00e9dicas (ICBM), Facultad Medicina (G.S., Z.P., S.L.), Universidad de Chile, Santiago."},{"name":"Department of Internal Medicine (Cardiology Division) (J.A.H., S.L.), University of Texas Southwestern Medical Center, Dallas."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41569-019-0244-8"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2010.203075"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1126\/science.451565"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2018.07.022"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-201x.2001.00788.x"}],"container-title":["Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCULATIONAHA.122.061322","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,29]],"date-time":"2025-05-29T14:24:32Z","timestamp":1748528672000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCULATIONAHA.122.061322"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,3]]},"references-count":5,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,9,3]]}},"alternative-id":["10.1161\/CIRCULATIONAHA.122.061322"],"URL":"https:\/\/doi.org\/10.1161\/circulationaha.122.061322","relation":{},"ISSN":["0009-7322","1524-4539"],"issn-type":[{"value":"0009-7322","type":"print"},{"value":"1524-4539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,3]]},"assertion":[{"value":"2024-09-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}