{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T18:59:37Z","timestamp":1790017177927,"version":"4.0.1"},"reference-count":119,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[2026,9,22]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Acute coronary syndrome (ACS) remains underrecognized in patients with Kawasaki disease (KD). The population at risk for KD-associated ACS is increasing, yet current ACS guidelines are largely derived from atherosclerotic disease and do not adequately address the distinctive mechanisms, anatomy, and thrombosis risk associated with KD. Because the pathophysiology and management of KD-associated ACS differ in fundamental ways from those of atherosclerotic coronary artery disease, its management requires a coordinated team response, with collaboration between pediatric and adult cardiologists. Recent advances in coronary imaging, interventional techniques, and antithrombotic therapies provide an opportunity to establish a more disease-specific approach. This review synthesizes current evidence on the epidemiology and pathophysiology of coronary artery aneurysms, interventional coronary imaging, acute management, revascularization strategies, antithrombotic therapy, and post-ACS surveillance in patients with KD to guide clinical decision-making and treatment for patients with KD presenting with ACS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/circulationaha.126.080727","type":"journal-article","created":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T18:00:16Z","timestamp":1790013616000},"page":"1135-1150","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Acute Coronary Syndrome in Kawasaki Disease From Infancy to Adulthood"],"prefix":"10.1161","volume":"154","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5145-0341","authenticated-orcid":true,"given":"Pei-Ni","family":"Jone","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Pediatric Cardiology, Ann &amp; Robert Lurie Children\u2019s Hospital of Chicago, Northwestern University Feinberg School of Medicine, IL (P.-N.J.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7794-9017","authenticated-orcid":true,"given":"Jane W.","family":"Newburger","sequence":"additional","affiliation":[{"name":"Departments of Cardiology (J.W.N.), Boston Children\u2019s Hospital, MA."},{"name":"Departments of Pediatrics (J.W.N.), Harvard Medical School, Boston, MA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5679-1217","authenticated-orcid":true,"given":"Jane C.","family":"Burns","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Rady Children\u2019s Hospital, University of California San Diego (J.C.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5626-0467","authenticated-orcid":true,"given":"Matthew I.","family":"Tomey","sequence":"additional","affiliation":[{"name":"Mount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, New York, NY (M.I.T.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3580-2268","authenticated-orcid":true,"given":"Andr\u00e9","family":"Jakob","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology and Pediatric Intensive Care, Ludwig-Maximilians-University of Munich, Germany (A.J.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4150-0899","authenticated-orcid":true,"given":"Yasutsugu","family":"Shiono","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Medicine, Wakayama Medical University, Japan (Y.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9481-8860","authenticated-orcid":true,"given":"Satsuki","family":"Fukushima","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, National Cerebral and Cardiovascular Center, Osaka, Japan (S.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6038-8161","authenticated-orcid":true,"given":"Yoshihide","family":"Mitani","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Mie University Graduate School of Medicine, Japan (Y.M.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1718-7137","authenticated-orcid":true,"given":"Ming-Tai","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, National Taiwan University Children\u2019s Hospital, Taipei (M.-T.L.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1969-421X","authenticated-orcid":true,"given":"Alain","family":"Fraisse","sequence":"additional","affiliation":[{"name":"Paediatric Cardiology Services, Royal Brompton &amp; Harefield NHS Foundation Trust, London, UK (A.F.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4972-3723","authenticated-orcid":true,"given":"Hirosyohi","family":"Yokoi","sequence":"additional","affiliation":[{"name":"Cardiovascular Center, Fukuoka Sanno Hospital, Fukuoka, Japan (H.Y.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8655-0203","authenticated-orcid":true,"given":"Tosihiro","family":"Tamura","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Tenri Hospital, Japan (T.T.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9882-6596","authenticated-orcid":true,"given":"Nadine","family":"Choueiter","sequence":"additional","affiliation":[{"name":"Mount Sinai Children\u2019s Heart Center, New York, NY (N.C.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiken","family":"Bhatt","sequence":"additional","affiliation":[{"name":"San Diego Cardiac Center, CA (J.B., J.B.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis G.","family":"Quinonez","sequence":"additional","affiliation":[{"name":"Cardiac Surgery (L.G.Q.), Boston Children\u2019s Hospital, MA."},{"name":"Surgery (L.G.Q.), Harvard Medical School, Boston, MA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etsuko","family":"Tsuda","sequence":"additional","affiliation":[{"name":"Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, Osaka, Japan (E.T.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7715-3169","authenticated-orcid":true,"given":"Nagib","family":"Dahdah","sequence":"additional","affiliation":[{"name":"Division of Pediatric Cardiology, CHU Ste-Justine, University of Montreal, Canada (N.D.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John B.","family":"Gordon","sequence":"additional","affiliation":[{"name":"San Diego Cardiac Center, CA (J.B., J.B.G.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9540-2648","authenticated-orcid":true,"given":"Kenji","family":"Suda","sequence":"additional","affiliation":[{"name":"Department of Pediatrics and Child Health, Kurume University School of Medicine, Fukuoka, Japan (K.S.)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/1756-185X.13214"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000001295"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2020.02.033"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000001309"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/ped.70007"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.119.016440"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2020.01.016"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-009-9599-7"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2018.0030"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-17-0433"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2025.26396"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2012.12.011"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.082107"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951110001502"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2019.00275"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000484"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-19-1094"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2019.01.092"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0022-3476(84)80114-6"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0022-3476(86)80928-3"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2025.114638"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2019-315925"},{"key":"e_1_3_3_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2024.114233"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcha.2022.101039"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2015.12.011"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.94.6.1379"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.04.102"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.124.034248"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2018.05.021"},{"key":"e_1_3_3_31_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0038998"},{"key":"e_1_3_3_32_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacadv.2024.100937"},{"key":"e_1_3_3_33_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.818609"},{"key":"e_1_3_3_34_2","doi-asserted-by":"publisher","DOI":"10.1253\/circj.71.709"},{"key":"e_1_3_3_35_2","doi-asserted-by":"publisher","DOI":"10.1007\/s002460010180"},{"key":"e_1_3_3_36_2","doi-asserted-by":"publisher","DOI":"10.1111\/1756-185X.13207"},{"key":"e_1_3_3_37_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.978213"},{"key":"e_1_3_3_38_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1216063"},{"key":"e_1_3_3_39_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs411"},{"key":"e_1_3_3_40_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000151311.38708.29"},{"key":"e_1_3_3_41_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.101.25.2935"},{"key":"e_1_3_3_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2017.05.055"},{"key":"e_1_3_3_43_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.carpath.2022.107456"},{"key":"e_1_3_3_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2016.11.055"},{"key":"e_1_3_3_45_2","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2021.630462"},{"key":"e_1_3_3_46_2","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2024-327190"},{"key":"e_1_3_3_47_2","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keac217"},{"key":"e_1_3_3_48_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.115.001939"},{"key":"e_1_3_3_49_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.113.001764"},{"key":"e_1_3_3_50_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.70432"},{"key":"e_1_3_3_51_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.04.020"},{"key":"e_1_3_3_52_2","doi-asserted-by":"publisher","DOI":"10.1186\/1546-0096-12-12"},{"key":"e_1_3_3_53_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41390-024-03431-w"},{"key":"e_1_3_3_54_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.30457"},{"key":"e_1_3_3_55_2","doi-asserted-by":"publisher","DOI":"10.1536\/ihj.21-593"},{"key":"e_1_3_3_56_2","doi-asserted-by":"publisher","DOI":"10.4244\/EIJY19M06_02"},{"key":"e_1_3_3_57_2","doi-asserted-by":"publisher","DOI":"10.1002\/ccd.30458"},{"key":"e_1_3_3_58_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2015.03.036"},{"key":"e_1_3_3_59_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1415098"},{"key":"e_1_3_3_60_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2020.09.014"},{"key":"e_1_3_3_61_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacadv.2025.101893"},{"key":"e_1_3_3_62_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jscai.2024.102294"},{"key":"e_1_3_3_63_2","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/5590109"},{"key":"e_1_3_3_64_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jjcc.2025.01.008"},{"key":"e_1_3_3_65_2","doi-asserted-by":"publisher","DOI":"10.1093\/ehjcr\/ytac186"},{"key":"e_1_3_3_66_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.19020"},{"key":"e_1_3_3_67_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.121.011408"},{"key":"e_1_3_3_68_2","doi-asserted-by":"publisher","DOI":"10.1111\/ped.12187"},{"key":"e_1_3_3_69_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2014.04.040"},{"key":"e_1_3_3_70_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcin.2023.09.021"},{"key":"e_1_3_3_71_2","doi-asserted-by":"publisher","DOI":"10.1093\/ehjacc\/zuad107"},{"key":"e_1_3_3_72_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(25)01562-4"},{"key":"e_1_3_3_73_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehaf423"},{"key":"e_1_3_3_74_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12969-022-00767-7"},{"key":"e_1_3_3_75_2","doi-asserted-by":"publisher","DOI":"10.21037\/cdt-24-289"},{"key":"e_1_3_3_76_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2020.07.022"},{"key":"e_1_3_3_77_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2015.11.032"},{"key":"e_1_3_3_78_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2023.10.010"},{"key":"e_1_3_3_79_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2022.09.031"},{"key":"e_1_3_3_80_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2023.43801"},{"key":"e_1_3_3_81_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.114.302699"},{"key":"e_1_3_3_82_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2019.07.064"},{"key":"e_1_3_3_83_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-013-0746-9"},{"key":"e_1_3_3_84_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2003.08.030"},{"key":"e_1_3_3_85_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.84.2.625"},{"key":"e_1_3_3_86_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12519-021-00452-x"},{"key":"e_1_3_3_87_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCGEN.118.002433"},{"key":"e_1_3_3_88_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12350-022-03041-1"},{"key":"e_1_3_3_89_2","doi-asserted-by":"publisher","DOI":"10.14814\/phy2.70096"},{"key":"e_1_3_3_90_2","doi-asserted-by":"publisher","DOI":"10.1253\/circj.cj-08-0121"},{"key":"e_1_3_3_91_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jjcc.2010.06.006"},{"key":"e_1_3_3_92_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12350-018-1278-8"},{"key":"e_1_3_3_93_2","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD014808.pub2"},{"key":"e_1_3_3_94_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.840603"},{"key":"e_1_3_3_95_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaccas.2025.105861"},{"key":"e_1_3_3_96_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2019.03.079"},{"key":"e_1_3_3_97_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2020.03.013"},{"key":"e_1_3_3_98_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11748-019-01215-2"},{"key":"e_1_3_3_99_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-010-9838-y"},{"key":"e_1_3_3_100_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2023.04.003"},{"key":"e_1_3_3_101_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000618"},{"key":"e_1_3_3_102_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocmr.2025.102671"},{"key":"e_1_3_3_103_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(25)01586-7"},{"key":"e_1_3_3_104_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.125.047790"},{"key":"e_1_3_3_105_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.211780"},{"key":"e_1_3_3_106_2","doi-asserted-by":"publisher","DOI":"10.1148\/radiol.241479"},{"key":"e_1_3_3_107_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-10951-0"},{"key":"e_1_3_3_108_2","doi-asserted-by":"publisher","DOI":"10.4070\/kcj.2011.41.2.53"},{"key":"e_1_3_3_109_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00246-016-1480-x"},{"key":"e_1_3_3_110_2","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951121002031"},{"key":"e_1_3_3_111_2","doi-asserted-by":"publisher","DOI":"10.1017\/S1047951124026593"},{"key":"e_1_3_3_112_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2010.01.032"},{"key":"e_1_3_3_113_2","doi-asserted-by":"publisher","DOI":"10.3390\/children6020016"},{"key":"e_1_3_3_114_2","doi-asserted-by":"publisher","DOI":"10.1515\/med-2021-0242"},{"key":"e_1_3_3_115_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.xjon.2024.10.016"},{"key":"e_1_3_3_116_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2007.03.034"},{"key":"e_1_3_3_117_2","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2018.33.e267"},{"key":"e_1_3_3_118_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41431-025-01930-w"},{"key":"e_1_3_3_119_2","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.121.023310"},{"key":"e_1_3_3_120_2","doi-asserted-by":"publisher","DOI":"10.1111\/ped.13500"}],"container-title":["Circulation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/CIRCULATIONAHA.126.080727","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T18:00:31Z","timestamp":1790013631000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCULATIONAHA.126.080727"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,22]]},"references-count":119,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2026,9,22]]}},"alternative-id":["10.1161\/CIRCULATIONAHA.126.080727"],"URL":"https:\/\/doi.org\/10.1161\/circulationaha.126.080727","relation":{},"ISSN":["0009-7322","1524-4539"],"issn-type":[{"value":"0009-7322","type":"print"},{"value":"1524-4539","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,22]]},"assertion":[{"value":"2026-09-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}