{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T18:39:39Z","timestamp":1773081579081,"version":"3.50.1"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"13","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Circulation"],"published-print":{"date-parts":[[2001,9,25]]},"abstract":"<jats:p>\n            <jats:bold>\n              <jats:italic>\n                <jats:bold>\n                  <jats:italic>Background<\/jats:italic>\n                <\/jats:bold>\n              <\/jats:italic>\n            <\/jats:bold>\n            The atrial musculature in the cavotricuspid isthmus is a part of posterior inputs to the AV node. In patients with typical atrial flutter, effects of radiofrequency ablation of this isthmus on AV node conduction are still unknown.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>\n                <jats:bold>\n                  <jats:italic>Methods and Results<\/jats:italic>\n                <\/jats:bold>\n              <\/jats:italic>\n            <\/jats:bold>\n            This study included 16 patients with clinically documented typical atrial flutter. Group 1 had 8 patients without and group 2 had 8 patients with dual AV nodal pathway physiology. Electrical pacing from the interatrial septum and low right atrium was performed to evaluate antegrade AV node function before and after ablation of the cavotricuspid isthmus. In group 1, the AV node conduction properties were similar before and after ablation. In group 2, the AV node Wenckebach cycle length and maximal AH interval during low right atrium (356\u00b158 versus 399\u00b149 ms,\n            <jats:italic>P<\/jats:italic>\n            =0.008; 303\u00b157 versus 376\u00b150 ms,\n            <jats:italic>P<\/jats:italic>\n            =0.008) and interatrial septum (365\u00b162 versus 393\u00b159 ms,\n            <jats:italic>P<\/jats:italic>\n            =0.008; 324\u00b152 versus 390\u00b160 ms,\n            <jats:italic>P<\/jats:italic>\n            =0.008) pacing were significantly longer after ablation. Elimination of the slow pathway after ablation was noted in 2 patients, including 1 with AV nodal reentrant echo beats.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>\n                <jats:bold>\n                  <jats:italic>Conclusions<\/jats:italic>\n                <\/jats:bold>\n              <\/jats:italic>\n            <\/jats:bold>\n            Radiofrequency ablation of the cavotricuspid isthmus was effective in eliminating typical atrial flutter without injury of antegrade fast AV node conduction. The atrial musculature in the cavotricuspid isthmus significantly contributed to the slow AV node conduction.\n          <\/jats:p>","DOI":"10.1161\/hc3801.078813","type":"journal-article","created":{"date-parts":[[2007,9,28]],"date-time":"2007-09-28T18:31:09Z","timestamp":1191004269000},"page":"1501-1505","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["Effects of Cavotricuspid Isthmus Ablation on Atrioventricular Node Electrophysiology in Patients With Typical Atrial Flutter"],"prefix":"10.1161","volume":"104","author":[{"given":"Ching-Tai","family":"Tai","sequence":"first","affiliation":[{"name":"From the Division of Cardiology, Department of Medicine, Cardiovascular Research Center, National Yang-Ming University School of Medicine, and Taipei Veterans General Hospital (C.-T.T., C.-F.T., M.-H.H., W.-S.L., Y.-K.L., W.-C.Y., Y.-A.D., M.-S.C., S.-A.C.), and Taipei Shin-Kong Memorial Hospital (S.-H.L.), Taipei, Taiwan, ROC."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chin-Feng","family":"Tsai","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Department of Medicine, Cardiovascular Research Center, National Yang-Ming University School of Medicine, and Taipei Veterans General Hospital (C.-T.T., C.-F.T., M.-H.H., W.-S.L., Y.-K.L., W.-C.Y., Y.-A.D., M.-S.C., S.-A.C.), and Taipei Shin-Kong Memorial Hospital (S.-H.L.), Taipei, Taiwan, ROC."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming-Hsiung","family":"Hsieh","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Department of Medicine, Cardiovascular Research Center, National Yang-Ming University School of Medicine, and Taipei Veterans General Hospital (C.-T.T., C.-F.T., M.-H.H., W.-S.L., Y.-K.L., W.-C.Y., Y.-A.D., M.-S.C., S.-A.C.), and Taipei Shin-Kong Memorial Hospital (S.-H.L.), Taipei, Taiwan, ROC."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-Shiang","family":"Lin","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Department of Medicine, Cardiovascular Research Center, National Yang-Ming University School of Medicine, and Taipei Veterans General Hospital (C.-T.T., C.-F.T., M.-H.H., W.-S.L., Y.-K.L., W.-C.Y., Y.-A.D., M.-S.C., S.-A.C.), and Taipei Shin-Kong Memorial Hospital (S.-H.L.), Taipei, Taiwan, ROC."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yung-Kuo","family":"Lin","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Department of Medicine, Cardiovascular Research Center, National Yang-Ming University School of Medicine, and Taipei Veterans General Hospital (C.-T.T., C.-F.T., M.-H.H., W.-S.L., Y.-K.L., W.-C.Y., Y.-A.D., M.-S.C., S.-A.C.), and Taipei Shin-Kong Memorial Hospital (S.-H.L.), Taipei, Taiwan, ROC."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shih-Huang","family":"Lee","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Department of Medicine, Cardiovascular Research Center, National Yang-Ming University School of Medicine, and Taipei Veterans General Hospital (C.-T.T., C.-F.T., M.-H.H., W.-S.L., Y.-K.L., W.-C.Y., Y.-A.D., M.-S.C., S.-A.C.), and Taipei Shin-Kong Memorial Hospital (S.-H.L.), Taipei, Taiwan, ROC."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Chung","family":"Yu","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Department of Medicine, Cardiovascular Research Center, National Yang-Ming University School of Medicine, and Taipei Veterans General Hospital (C.-T.T., C.-F.T., M.-H.H., W.-S.L., Y.-K.L., W.-C.Y., Y.-A.D., M.-S.C., S.-A.C.), and Taipei Shin-Kong Memorial Hospital (S.-H.L.), Taipei, Taiwan, ROC."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-An","family":"Ding","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Department of Medicine, Cardiovascular Research Center, National Yang-Ming University School of Medicine, and Taipei Veterans General Hospital (C.-T.T., C.-F.T., M.-H.H., W.-S.L., Y.-K.L., W.-C.Y., Y.-A.D., M.-S.C., S.-A.C.), and Taipei Shin-Kong Memorial Hospital (S.-H.L.), Taipei, Taiwan, ROC."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mau-Song","family":"Chang","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Department of Medicine, Cardiovascular Research Center, National Yang-Ming University School of Medicine, and Taipei Veterans General Hospital (C.-T.T., C.-F.T., M.-H.H., W.-S.L., Y.-K.L., W.-C.Y., Y.-A.D., M.-S.C., S.-A.C.), and Taipei Shin-Kong Memorial Hospital (S.-H.L.), Taipei, Taiwan, ROC."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shih-Ann","family":"Chen","sequence":"additional","affiliation":[{"name":"From the Division of Cardiology, Department of Medicine, Cardiovascular Research Center, National Yang-Ming University School of Medicine, and Taipei Veterans General Hospital (C.-T.T., C.-F.T., M.-H.H., W.-S.L., Y.-K.L., W.-C.Y., Y.-A.D., M.-S.C., S.-A.C.), and Taipei Shin-Kong Memorial Hospital (S.-H.L.), Taipei, Taiwan, 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