{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T02:43:31Z","timestamp":1781664211950,"version":"3.54.5"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Stroke"],"published-print":{"date-parts":[[2002,2]]},"abstract":"<jats:p>\n            <jats:bold>\n              <jats:italic>\n                <jats:bold>\n                  <jats:italic>Background and Purpose<\/jats:italic>\n                <\/jats:bold>\n                \u2014\n              <\/jats:italic>\n            <\/jats:bold>\n            Cerebral venous pressure is governed by intracranial pressure, cerebral perfusion pressure, and venous outflow resistance. Therefore, changes in venous flow velocities are to be expected because of changes in intracranial pressure and brain tissue dislocation in patients with ischemic stroke and space-occupying brain edema.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>\n                <jats:bold>\n                  <jats:italic>Methods<\/jats:italic>\n                <\/jats:bold>\n                \u2014\n              <\/jats:italic>\n            <\/jats:bold>\n            In 21 prospectively recruited patients with middle cerebral artery stroke and postischemic edema, flow velocities in the basal veins, the vein of Galen, the straight sinus, and the P2 segment of the posterior cerebral artery were recorded every 0.9\u00b10.5 days during the first 5 days after symptom onset with the use of transcranial color-coded duplex sonography. The midline shift of the third ventricle was determined by B-mode imaging.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>\n                <jats:bold>\n                  <jats:italic>Results<\/jats:italic>\n                <\/jats:bold>\n                \u2014\n              <\/jats:italic>\n            <\/jats:bold>\n            We observed an initial increase of flow velocity in the basal vein ipsilateral to the lesion, followed by a significant decrease within 5 days after symptom onset and with increasing midline shift in patients with brain herniation. In the straight sinus, flow velocity showed a biphasic U-shaped response to increasing dislocation of the third ventricle, with an initial decrease followed by an increase in the course of mass movement (midline shift 1 to 1.5 cm). A steep increase of flow velocity in the vein of Galen took place with a midline shift &gt;1.5 cm. In the survivors these changes could not be observed. Flow velocity in the P2 segment of the posterior cerebral artery followed a typical course in neither the fatal cases nor the survivors.\n          <\/jats:p>\n          <jats:p>\n            <jats:bold>\n              <jats:italic>\n                <jats:bold>\n                  <jats:italic>ConclusionsA<\/jats:italic>\n                <\/jats:bold>\n                \u2014\n              <\/jats:italic>\n            <\/jats:bold>\n            Monitoring of flow velocities in the basal cerebral veins and in the straight sinus can provide additional pathophysiological information in patients with space-occupying brain edema after acute stroke.\n          <\/jats:p>","DOI":"10.1161\/hs0202.102371","type":"journal-article","created":{"date-parts":[[2002,7,28]],"date-time":"2002-07-28T23:16:47Z","timestamp":1027898207000},"page":"479-485","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":18,"title":["Intracranial Venous Hemodynamics in Patients With Midline Dislocation Due to Postischemic Brain Edema"],"prefix":"10.1161","volume":"33","author":[{"given":"Erwin","family":"Stolz","sequence":"first","affiliation":[{"name":"From the Department of Neurology, Justus-Liebig University, Giessen, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tibo","family":"Gerriets","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Justus-Liebig University, Giessen, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sait Seymen","family":"Babacan","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Justus-Liebig University, Giessen, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Jauss","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Justus-Liebig University, Giessen, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jo\u0308rg","family":"Kraus","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Justus-Liebig University, Giessen, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manfred","family":"Kaps","sequence":"additional","affiliation":[{"name":"From the Department of Neurology, Justus-Liebig University, Giessen, Germany."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_1_1_2","doi-asserted-by":"crossref","first-page":"745","DOI":"10.3171\/jns.1988.68.5.0745","volume":"68","year":"1988","unstructured":"Hassler W, Steinmetz H, Gawlowski J. Transcranial Doppler ultrasonography in raised intracranial pressure and in intracranial circulatory arrest. J Neurosurg. 1988; 68: 745\u2013751.","journal-title":"J Neurosurg"},{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.3171\/jns.1989.71.2.0195"},{"key":"e_1_3_1_3_2","doi-asserted-by":"crossref","unstructured":"Aaslid R Lindegaard KF. Cerebral hemodynamics.In: Aaslid R ed. Transcranial Doppler Sonography. New York NY: Springer; 1986: 65\u201385.","DOI":"10.1007\/978-3-7091-8864-4_5"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/str.30.5.1070"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1111\/jon19955287"},{"key":"e_1_3_1_6_2","first-page":"1771","volume":"18","year":"1997","unstructured":"Baumgartner RW, G\u00f6nner F, Arnold M, M\u00fcri RM. Transtemporal power- and frequency-based color coded duplex sonography of cerebral veins and sinuses. 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