{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T10:16:15Z","timestamp":1794305775347,"version":"4.9.0"},"reference-count":62,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Hypertension"],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:sec>\n            <jats:title>BACKGROUND:<\/jats:title>\n            <jats:p>Chronic hypertension is known to be a major contributor to cognitive decline, with executive function and working memory being among the domains most commonly affected. Despite the growing literature on such dysfunction in patients with hypertension, the underlying neural processes are poorly understood.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>METHODS:<\/jats:title>\n            <jats:p>In this cross-sectional study, we examine these neural processes by having participants with controlled hypertension, uncontrolled hypertension, and healthy controls perform a verbal working memory task during magnetoencephalography. Neural oscillations associated with the encoding and maintenance components of the working memory task were imaged and statistically evaluated among the 3 groups.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>RESULTS:<\/jats:title>\n            <jats:p>Differences related to hypertension emerged during the encoding phase, where the hypertension groups exhibited weaker \u03b1-\u03b2 oscillatory responses compared with controls in the left parietal cortices, whereas such oscillatory activity differed between the 2 hypertension groups in the right prefrontal regions. Importantly, these neural responses in the prefrontal and parietal cortices during encoding were also significantly associated with behavioral performance across all participants.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>CONCLUSIONS:<\/jats:title>\n            <jats:p>Overall, our data suggest that hypertension is associated with neurophysiological abnormalities during working memory encoding, whereas the neural processes serving maintenance seem to be preserved. The right hemispheric neural responses likely reflected compensatory processing, which patients with controlled hypertension may use to achieve verbal working memory function at the level of controls, as opposed to the uncontrolled hypertension group where diminished resources may have limited such additional recruitment.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/hypertensionaha.124.22698","type":"journal-article","created":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T05:01:01Z","timestamp":1714539661000},"page":"1609-1618","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Hypertension Impacts the Oscillatory Dynamics Serving the Encoding Phase of Verbal Working Memory"],"prefix":"10.1161","volume":"81","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7612-6871","authenticated-orcid":true,"given":"Yasra","family":"Arif","sequence":"first","affiliation":[{"name":"Institute for Human Neuroscience, Boys Town National Research Hospital, Boys Town, NE (Y.A., A.D.K., M.P.W., H.J.O., H.J.J., T.W.W.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abraham D.","family":"Killanin","sequence":"additional","affiliation":[{"name":"Institute for Human Neuroscience, Boys Town National Research Hospital, Boys Town, NE (Y.A., A.D.K., M.P.W., H.J.O., H.J.J., T.W.W.)."},{"name":"College of Medicine, University of Nebraska Medical Center, Omaha, NE (A.D.K., T.W.W.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-7221-5645","authenticated-orcid":true,"given":"Jingqi","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Psychology, University of Michigan, Ann Arbor, MI (J.Z.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7355-4459","authenticated-orcid":true,"given":"Madelyn P.","family":"Willett","sequence":"additional","affiliation":[{"name":"Institute for Human Neuroscience, Boys Town National Research Hospital, Boys Town, NE (Y.A., A.D.K., M.P.W., H.J.O., H.J.J., T.W.W.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8116-6832","authenticated-orcid":true,"given":"Hannah J.","family":"Okelberry","sequence":"additional","affiliation":[{"name":"Institute for Human Neuroscience, Boys Town National Research Hospital, Boys Town, NE (Y.A., A.D.K., M.P.W., H.J.O., H.J.J., T.W.W.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hallie J.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Institute for Human Neuroscience, Boys Town National Research Hospital, Boys Town, NE (Y.A., A.D.K., M.P.W., H.J.O., H.J.J., T.W.W.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5053-8306","authenticated-orcid":true,"given":"Tony W.","family":"Wilson","sequence":"additional","affiliation":[{"name":"Institute for Human Neuroscience, Boys Town National Research Hospital, Boys Town, NE (Y.A., A.D.K., M.P.W., H.J.O., H.J.J., T.W.W.)."},{"name":"College of Medicine, University of Nebraska Medical Center, Omaha, NE (A.D.K., T.W.W.)."},{"name":"Department of Pharmacology and Neuroscience, Creighton University, Omaha, NE (T.W.W.)."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0b013e3182299496"},{"key":"e_1_3_3_3_2","unstructured":"World Health Organization. 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