{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T02:16:44Z","timestamp":1788833804376,"version":"build-2803163510"},"reference-count":70,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["Hypertension"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:sec>\n            <jats:title>BACKGROUND:<\/jats:title>\n            <jats:p>Hypertension is the most common chronic disease and a major modifiable risk factor for cardio-cerebrovascular and renal diseases. This study estimated the national burden of hypertension, defined as systolic blood pressure \u2265140 mm\u2005Hg, on morbidity and mortality in 2021 in France.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>METHODS:<\/jats:title>\n            <jats:p>For all diseases causally associated with hypertension (cardiovascular diseases, chronic kidney diseases, and dementia), the number and proportion of cases attributable to hypertension in adults aged \u226535 years were estimated using population attributable fractions. Age- and sex-specific population attributable fractions were computed using the distribution of hypertension in the French population. These population attributable fractions were applied to nationwide statistics for mortality, hospitalizations, disease prevalence, years of life lost, years of life lived with disability, and disability-adjusted years of life.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>RESULTS:<\/jats:title>\n            <jats:p>The largest population attributable fractions were for ischemic heart disease and hemorrhagic stroke, with over 40% of cases attributable to hypertension. Overall, more than 385\u2005000 patients were hospitalized due to hypertension, with 3.7 million hospitalizations and 6.2 million hospital days (all hospitalizations, including 3.4 million for chronic kidney disease) and including 390\u2005000 overnight hospitalization. In 2021, more than 1.15 million individuals lived with ischemic heart disease attributable to hypertension, 1.26 million with chronic kidney diseases, and 358\u2005033 with heart failure. Among 184\u2005059 annual deaths from cardiovascular diseases, dementia, and chronic kidney diseases, 30% (55\u2005280 deaths) were attributable to hypertension. Hypertension accounted for 8.5% of all deaths and 498\u2005052 years of life lost.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>CONCLUSIONS:<\/jats:title>\n            <jats:p>In France, despite near-universal health coverage and free health care access, the burden attributable to hypertension remains high.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/hypertensionaha.124.23760","type":"journal-article","created":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T10:00:43Z","timestamp":1733738443000},"page":"357-369","update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":15,"title":["Burden of Cardio-Cerebrovascular and Renal Diseases Attributable to Systolic Hypertension in France in 2021"],"prefix":"10.1161","volume":"82","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2843-1510","authenticated-orcid":true,"given":"Cl\u00e9mence","family":"Grave","sequence":"first","affiliation":[{"name":"Direction des maladies non transmissibles, Sant\u00e9 publique France, Saint-Maurice, France (C.G., A.G., M.J.T., V.O.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8939-6205","authenticated-orcid":true,"given":"Christophe","family":"Bonaldi","sequence":"additional","affiliation":[{"name":"Direction Appui, Traitements et Analyses de donn\u00e9es, Sant\u00e9 publique France, Saint-Maurice, France (C.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1556-8590","authenticated-orcid":true,"given":"Laure","family":"Carcaillon-Bentata","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Bordeaux, Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale (INSERM) Centre d\u2019Investigation Clinique Plurith\u00e9matique (CIC-P) 1401, Bordeaux PharmacoEpi, Bordeaux, France (L.C.-B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1273-8988","authenticated-orcid":true,"given":"Am\u00e9lie","family":"Gabet","sequence":"additional","affiliation":[{"name":"Direction des maladies non transmissibles, Sant\u00e9 publique France, Saint-Maurice, France (C.G., A.G., M.J.T., V.O.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0723-7735","authenticated-orcid":true,"given":"Jean-Michel","family":"Halimi","sequence":"additional","affiliation":[{"name":"Service de N\u00e9phrologie-hypertension, Dialyses, Transplantation R\u00e9nale, H\u00f4pital Bretonneau et h\u00f4pital Clocheville, France (J.-M.H.)."},{"name":"INSERM U1327, Universit\u00e9 de Tours, Tours, France (J.-M.H.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6517-2984","authenticated-orcid":true,"given":"Christophe","family":"Tzourio","sequence":"additional","affiliation":[{"name":"Universit\u00e9 de Bordeaux, Inserm, Bordeaux Population Health Research Center, Unit\u00e9 Mixte de Recherche (UMR) 1219, CHU Bordeaux, Bordeaux, France (C.T.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7848-7072","authenticated-orcid":true,"given":"Yannick","family":"B\u00e9jot","sequence":"additional","affiliation":[{"name":"Service de neurologie, CHU Dijon Bourgogne, Universit\u00e9 de Bourgogne, Dijon, France (Y.B.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marion J.","family":"Torres","sequence":"additional","affiliation":[{"name":"Direction des maladies non transmissibles, Sant\u00e9 publique France, Saint-Maurice, France (C.G., A.G., M.J.T., V.O.)."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6896-2941","authenticated-orcid":true,"given":"Philippe Gabriel","family":"Steg","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris Cit\u00e9, Assistance Publique - 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