{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T17:02:11Z","timestamp":1776704531694,"version":"3.51.2"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2013,3,12]]},"abstract":"\n Background<\/jats:title>\n \n Major advances have been made in the treatment of\n ST<\/jats:styled-content>\n \u2010elevation myocardial infarction (\n STEMI<\/jats:styled-content>\n ) in outpatients. In contrast, little is known about outcomes in\n STEMI<\/jats:styled-content>\n that occur in patients hospitalized for a noncardiac condition.\n <\/jats:p>\n <\/jats:sec>\n \n Methods and Results<\/jats:title>\n \n This was a retrospective, single\u2010center study of inpatient\n STEMI<\/jats:styled-content>\n s from January 1, 2007, to July 31, 2011. Forty\u2010eight cases were confirmed to be inpatient\n STEMI<\/jats:styled-content>\n s of a total of 139\u00a0410 adult discharges. These patients were older and more often female and had higher rates of chronic kidney disease and prior cerebrovascular events compared with 227 patients with outpatient\n STEMI<\/jats:styled-content>\n s treated during the same period. Onset of inpatient\n STEMI<\/jats:styled-content>\n was heralded most frequently by a change in clinical status (60%) and less commonly by patient complaints (33%) or changes on telemetry. Coronary angiography and percutaneous coronary intervention were performed in 71% and 56% of patients, respectively. The median time to obtain\n ECG<\/jats:styled-content>\n (41 [10, 600] versus 5 [2, 10] minutes;\n P<\/jats:italic>\n <0.001),\n ECG<\/jats:styled-content>\n to angiography time (91 [26, 209] versus 35 [25, 46] minutes;\n P<\/jats:italic>\n <0.001) and\n ECG<\/jats:styled-content>\n to first device activation (\n FDA<\/jats:styled-content>\n ) (129 [65, 25] versus 60 [47, 76] minutes;\n P<\/jats:italic>\n <0.001) were longer for inpatient versus outpatient\n STEMI<\/jats:styled-content>\n . Survival to discharge was lower for inpatient\n STEMI<\/jats:styled-content>\n (60% versus 96%;\n P<\/jats:italic>\n <0.001), and this difference persisted after adjusting for potential confounders.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Patients who develop a\n STEMI<\/jats:styled-content>\n while hospitalized for a noncardiac condition are older and more often female, have more comorbidities, have longer\n ECG<\/jats:styled-content>\n \u2010to\u2010\n FDA<\/jats:styled-content>\n times, and are less likely to survive than patients with an outpatient\n STEMI<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1161\/jaha.113.000004","type":"journal-article","created":{"date-parts":[[2013,5,24]],"date-time":"2013-05-24T16:49:31Z","timestamp":1369414171000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":40,"title":["Acute ST\u2010Elevation Myocardial Infarction in Patients Hospitalized for Noncardiac Conditions"],"prefix":"10.1161","volume":"2","author":[{"given":"Xuming","family":"Dai","sequence":"first","affiliation":[{"name":"Division of Cardiology, University of North Carolina, Chapel Hill, NC"},{"name":"McAllister Heart Institute, University of North Carolina, Chapel Hill, NC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph","family":"Bumgarner","sequence":"additional","affiliation":[{"name":"Division of Cardiology, University of North Carolina, Chapel Hill, NC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew","family":"Spangler","sequence":"additional","affiliation":[{"name":"Division of Cardiology, University of North Carolina, Chapel Hill, NC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dane","family":"Meredith","sequence":"additional","affiliation":[{"name":"Division of Cardiology, University of North Carolina, Chapel Hill, NC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"suffix":"Jr","given":"Sidney C.","family":"Smith","sequence":"additional","affiliation":[{"name":"Division of Cardiology, University of North Carolina, Chapel Hill, NC"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George A.","family":"Stouffer","sequence":"additional","affiliation":[{"name":"Division of Cardiology, University of North Carolina, Chapel Hill, NC"},{"name":"McAllister Heart Institute, University of North Carolina, Chapel Hill, NC"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.044107"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.09.011"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.192663"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(81)90225-8"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00629-X"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.166.13.1410"},{"key":"e_1_3_2_8_2","unstructured":"Healthcare Cost and Utilization Project Facts and Figures: Statistics on Hospital\u2010based Care in the United States 2009. Available at: http:\/\/www.hcup-us.ahrq.gov\/reports\/factsandfigures\/2009\/pdfs\/FF_2009_section2.pdf. Last Accessed October 26 2012."},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0908610"}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.113.000004","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T10:51:47Z","timestamp":1715597507000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.113.000004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,3,12]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013,3,12]]}},"alternative-id":["10.1161\/JAHA.113.000004"],"URL":"https:\/\/doi.org\/10.1161\/jaha.113.000004","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3,12]]},"assertion":[{"value":"2012-11-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-02-21","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2013-04-04","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e000004"}}