{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T10:33:58Z","timestamp":1790505238392,"version":"4.1.0"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2014,8,15]]},"abstract":"\n Background<\/jats:title>\n \n Changes in quality of life (QoL) after catheter ablation for long\u2010standing persistent atrial fibrillation (\n LSPAF<\/jats:styled-content>\n ) are not well described. We sought to compare QoL improvement after catheter ablation of paroxysmal atrial fibrillation (\n PAF<\/jats:styled-content>\n ) versus that after\n LSPAF<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Methods and Results<\/jats:title>\n \n A total of 261\n PAF<\/jats:styled-content>\n and 126\n LSPAF<\/jats:styled-content>\n ablation recipients were prospectively followed for arrhythmia recurrence, QoL, hospital stay, and sick leave. In\n PAF<\/jats:styled-content>\n versus\n LSPAF<\/jats:styled-content>\n groups, 1.3\u00b10.6 versus 1.6\u00b10.7 procedures were performed per patient (\n P<\/jats:italic>\n <0.00001) during a 3\u2010year follow\u2010up. Good arrhythmia control was achieved in 86% versus 87% of patients (\n P<\/jats:italic>\n =0.69) and in 69% versus 69% of patients not receiving antiarrhythmic drugs (\n P<\/jats:italic>\n =0.99). The baseline QoL was better in the\n PAF<\/jats:styled-content>\n than in the\n LSPAF<\/jats:styled-content>\n group (European Quality of Life Group instrument self\u2010report questionnaire visual analog scale: 66.4\u00b114.2 versus 61.0\u00b114.2,\n P<\/jats:italic>\n =0.0005; European Quality of Life Group 3\u2010level, 5\u2010dimensional descriptive system: 71.4\u00b19.2 versus 67.7\u00b113.8,\n P<\/jats:italic>\n =0.002). Postablation 3\u2010year increase in QoL was significant in both groups (all\n P<\/jats:italic>\n <0.00001) and significantly lower in\n PAF<\/jats:styled-content>\n versus\n LSPAF<\/jats:styled-content>\n patients (visual analog scale: +5.0\u00b114.5 versus +10.2\u00b112.8,\n P<\/jats:italic>\n =0.001; descriptive system: +5.9\u00b114.3 versus +9.3\u00b113.9,\n P<\/jats:italic>\n =0.03). In multivariate analysis,\n LSPAF<\/jats:styled-content>\n , less advanced age, shorter history of\n AF<\/jats:styled-content>\n and good arrhythmia control were consistently associated with postablation 3\u2010year improvement in QoL. Days of hospital stay for cardiovascular reasons and days on sick leave per patient\/year were significantly reduced in both groups.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Patients with\n LSPAF<\/jats:styled-content>\n had worse baseline QoL. The magnitude of QoL improvement after ablation of\n LSPAF<\/jats:styled-content>\n was significantly greater compared with after ablation of\n PAF<\/jats:styled-content>\n , particularly when good arrhythmia control was achieved without the use of antiarrhythmic drugs.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1161\/jaha.114.000881","type":"journal-article","created":{"date-parts":[[2014,7,19]],"date-time":"2014-07-19T05:19:26Z","timestamp":1405747166000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":34,"title":["Improvement in Quality of Life After Catheter Ablation for Paroxysmal Versus Long\u2010standing Persistent Atrial Fibrillation: A Prospective Study With 3\u2010Year Follow\u2010up"],"prefix":"10.1161","volume":"3","author":[{"given":"Veronika","family":"Bulkov\u00e1","sequence":"first","affiliation":[{"name":"Department of Cardiology and Angiology, St. Anne's University Hospital and International Clinical Research Center, Brno, Czech Republic"},{"name":"Department of Cardiology and Angiology, First Faculty of Medicine, Charles University, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin","family":"Fiala","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Cardiology, University Hospital, Masaryk University, Brno, Czech Republic"},{"name":"Department of Cardiology, Hospital Podles\u00ed, T\u0159inec, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0160t\u011bp\u00e1n","family":"Havr\u00e1nek","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology, First Faculty of Medicine, Charles University, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"\u0160imek","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology, First Faculty of Medicine, Charles University, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Libor","family":"\u0160k\u0148ou\u0159il","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital Podles\u00ed, T\u0159inec, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaroslav","family":"Janu\u0161ka","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Hospital Podles\u00ed, T\u0159inec, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jind\u0159ich","family":"\u0160pinar","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Cardiology, University Hospital, Masaryk University, Brno, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Wichterle","sequence":"additional","affiliation":[{"name":"Department of Cardiology and Angiology, First Faculty of Medicine, Charles University, Prague, Czech Republic"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq278"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2011.12.016"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2005.02.1037"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.293.21.2634"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.772582"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.111.966408"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.01.040"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.110.957563"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa050955"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa041018"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.01.069"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eut161"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10198-003-0182-5"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.hrthm.2011.04.012"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.109.859116"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.05.061"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-668X(03)00261-6"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2003.08.037"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.03.051"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(03)00577-1"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/JOM.0b013e31820fd1c9"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10198-008-0139-9"}],"container-title":["Journal 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