{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T22:18:12Z","timestamp":1792880292695,"version":"4.5.0"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2015,12]]},"abstract":"\n Background<\/jats:title>\n \n Air pollution is associated with greater cardiovascular event risk, but the types of events and specific persons at risk remain unknown. This analysis evaluates effects of short\u2010term exposure to fine particulate matter air pollution with risk of acute coronary syndrome events, including\n ST<\/jats:styled-content>\n \u2010segment elevation myocardial infarction, non\u2013\n ST<\/jats:styled-content>\n \u2010segment elevation myocardial infarction, unstable angina, and non\u2013\n ST<\/jats:styled-content>\n \u2010segment elevation acute coronary syndrome.\n <\/jats:p>\n <\/jats:sec>\n \n Methods and Results<\/jats:title>\n \n Acute coronary syndrome events treated at Intermountain Healthcare hospitals in urban areas of Utah's Wasatch Front were collected between September 1993 and May 2014 (N=16\u00a0314). A time\u2010stratified case\u2010crossover design was performed matching fine particulate matter air pollution exposure at the time of each event with referent periods when the event did not occur. Patients served as their own controls, and odds ratios were estimated using nonthreshold and threshold conditional logistic regression models. In patients with angiographic coronary artery disease, odds ratios for a 10\u2010\u03bcg\/m\n 3<\/jats:sup>\n increase in concurrent\u2010day fine particulate matter air pollution >25\u00a0\u03bcg\/m\u00b3 were 1.06 (95%\n CI<\/jats:styled-content>\n 1.02\u20131.11) for all acute coronary syndrome, 1.15 (95%\n CI<\/jats:styled-content>\n 1.03\u20131.29) for\n ST<\/jats:styled-content>\n \u2010segment elevation myocardial infarction, 1.02 (95%\n CI<\/jats:styled-content>\n 0.97\u20131.08) for non\u2013\n ST<\/jats:styled-content>\n \u2010segment elevation myocardial infarction, 1.09 (95%\n CI<\/jats:styled-content>\n 1.02\u20131.17) for unstable angina, and 1.05 (95%\n CI<\/jats:styled-content>\n 1.00\u20131.10) for non\u2013\n ST<\/jats:styled-content>\n \u2010segment elevation acute coronary syndrome events. Excess risk from fine particulate matter air pollution exposure was not observed in patients without angiographic coronary artery disease.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Elevated fine particulate matter air pollution exposures contribute to triggering acute coronary events, especially\n ST<\/jats:styled-content>\n \u2010segment elevation myocardial infarction, in those with existing seriously diseased coronary arteries but not in those with nondiseased coronary arteries.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1161\/jaha.115.002506","type":"journal-article","created":{"date-parts":[[2015,12,9]],"date-time":"2015-12-09T13:47:19Z","timestamp":1449668839000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":125,"title":["Short\u2010Term Exposure to Fine Particulate Matter Air Pollution Is Preferentially Associated With the Risk of ST\u2010Segment Elevation Acute Coronary Events"],"prefix":"10.1161","volume":"4","author":[{"suffix":"III","given":"C. Arden","family":"Pope","sequence":"first","affiliation":[{"name":"Department of Economics Brigham Young University Provo UT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph B.","family":"Muhlestein","sequence":"additional","affiliation":[{"name":"Intermountain Heart Institute Intermountain Medical Center Murray UT"},{"name":"Department of Internal Medicine University of Utah Salt Lake City UT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey L.","family":"Anderson","sequence":"additional","affiliation":[{"name":"Intermountain Heart Institute Intermountain Medical Center Murray UT"},{"name":"Department of Internal Medicine University of Utah Salt Lake City UT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John B.","family":"Cannon","sequence":"additional","affiliation":[{"name":"Department of Economics Brigham Young University Provo UT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas M.","family":"Hales","sequence":"additional","affiliation":[{"name":"Department of Economics Brigham Young University Provo UT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kent G.","family":"Meredith","sequence":"additional","affiliation":[{"name":"Intermountain Heart Institute Intermountain Medical Center Murray UT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viet","family":"Le","sequence":"additional","affiliation":[{"name":"Intermountain Heart Institute Intermountain Medical Center Murray UT"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin D.","family":"Horne","sequence":"additional","affiliation":[{"name":"Intermountain Heart Institute Intermountain Medical Center Murray UT"},{"name":"Department of Internal Medicine University of Utah Salt Lake City UT"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_1_2_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e3181dbece1"},{"key":"e_1_3_1_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpcardiol.2015.01.003"},{"key":"e_1_3_1_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000108927.80044.7F"},{"key":"e_1_3_1_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa054409"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.11449"},{"key":"e_1_3_1_7_2","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.1104660"},{"key":"e_1_3_1_8_2","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.1104049"},{"key":"e_1_3_1_9_2","doi-asserted-by":"publisher","DOI":"10.1186\/1476-069X-12-43"},{"key":"e_1_3_1_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)62158-3"},{"key":"e_1_3_1_11_2","doi-asserted-by":"publisher","DOI":"10.2337\/dc12-2189"},{"key":"e_1_3_1_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.116.305060"},{"key":"e_1_3_1_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61766-8"},{"key":"e_1_3_1_14_2","first-page":"1","article-title":"Particulate air pollution and nonfatal cardiac events. 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