{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:36:07Z","timestamp":1791225367805,"version":"4.1.0"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2016,3,9]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">Cardiovascular diseases (CVD) are the leading cause of death in the world, and diet plays a major role in CVD incidence, especially through lipid oxidation mechanisms. This, in turn, leads to tissue inflammation and formation of atheromatous plaques.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              Our objective was to evaluate the association between the inflammatory potential of the diet and the incidence of overall CVD or its subclasses. We included 7743 participants from the Suppl\u00e9mentation en Vitamines et Min\u00e9raux AntioXydants (SU.VI.MAX) cohort. All cardiovascular events were recorded using self\u2010reported information or clinical visits, and were validated. The dietary inflammatory index (DII) was computed using repeated 24\u2010hour dietary records (mean=9.5\u00b13.4 records\/subject). Hazard ratio and 95% CI for outcomes (CVD and subclasses) were estimated across sex\u2010specific quartiles of the DII using Cox proportional hazard models. A total of 292 cardiovascular events were recorded and validated during an average of 11.4\u00a0years of follow\u2010up: 93 myocardial infarctions, 58 strokes, 128 angina pectoris and revascularization interventions, and 13 sudden deaths. When considering CVD subclasses, a diet with pro\u2010inflammatory properties, as expressed by higher DII scores, was significantly associated with a higher risk of myocardial infarction (hazard ratio\n              <jats:sub>Quartile 4 versus Quartile 1<\/jats:sub>\n              =2.24, 95% CI: 1.08\u20134.67). No significant association was observed between the DII score and stroke or both angina pectoris and revascularization intervention.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">A pro\u2010inflammatory diet, as measured by a higher DII score, was prospectively associated with a higher risk of myocardial infarction. Promotion of a diet exhibiting anti\u2010inflammatory properties may help prevent myocardial infarctions.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.115.002735","type":"journal-article","created":{"date-parts":[[2016,3,16]],"date-time":"2016-03-16T02:53:41Z","timestamp":1458096821000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":77,"title":["Prospective Association Between the Dietary Inflammatory Index and Cardiovascular Diseases in the SUppl\u00e9mentation en VItamines et Min\u00e9raux AntioXydants (SU.VI.MAX) Cohort"],"prefix":"10.1161","volume":"5","author":[{"given":"Lola","family":"Neufcourt","sequence":"first","affiliation":[{"name":"Universit\u00e9 Paris 13, Equipe de Recherche en Epid\u00e9miologie Nutritionnelle (EREN), Centre d'Epid\u00e9miologie et Statistiques Sorbonne Paris Cit\u00e9, Inserm (U1153), Inra (U1125), Cnam, COMUE Sorbonne Paris Cit\u00e9, Bobigny, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karen E.","family":"Assmann","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris 13, Equipe de Recherche en Epid\u00e9miologie Nutritionnelle (EREN), Centre d'Epid\u00e9miologie et Statistiques Sorbonne Paris Cit\u00e9, Inserm (U1153), Inra (U1125), Cnam, COMUE Sorbonne Paris Cit\u00e9, Bobigny, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00e9opold K.","family":"Fezeu","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris 13, Equipe de Recherche en Epid\u00e9miologie Nutritionnelle (EREN), Centre d'Epid\u00e9miologie et Statistiques Sorbonne Paris Cit\u00e9, Inserm (U1153), Inra (U1125), Cnam, COMUE Sorbonne Paris Cit\u00e9, Bobigny, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathilde","family":"Touvier","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris 13, Equipe de Recherche en Epid\u00e9miologie 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SC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James R.","family":"H\u00e9bert","sequence":"additional","affiliation":[{"name":"Cancer Prevention and Control Program, Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC"},{"name":"Connecting Health Innovations LLC, Columbia, SC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael D.","family":"Wirth","sequence":"additional","affiliation":[{"name":"Cancer Prevention and Control Program, Department of Epidemiology and Biostatistics, Arnold School of Public Health, University of South Carolina, Columbia, SC"},{"name":"Connecting Health Innovations LLC, Columbia, SC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serge","family":"Hercberg","sequence":"additional","affiliation":[{"name":"Universit\u00e9 Paris 13, Equipe de Recherche en Epid\u00e9miologie Nutritionnelle (EREN), Centre d'Epid\u00e9miologie et 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