{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T16:23:51Z","timestamp":1791476631216,"version":"4.3.4"},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2016,3,9]]},"abstract":"\n Background<\/jats:title>\n \n The determination of appropriate duration of in\u2010the\u2010field cardiopulmonary resuscitation (\n CPR<\/jats:styled-content>\n ) for out\u2010of\u2010hospital cardiac arrest (\n OHCA<\/jats:styled-content>\n ) patients is one of the biggest challenges for emergency medical service providers and clinicians. The appropriate\n CPR<\/jats:styled-content>\n duration before termination of resuscitation remains unclear and may differ based on initial rhythm. We aimed to determine the relationship between\n CPR<\/jats:styled-content>\n duration and post\u2010\n OHCA<\/jats:styled-content>\n outcomes.\n <\/jats:p>\n <\/jats:sec>\n \n Methods and Results<\/jats:title>\n \n We analyzed the records of 17\u00a0238\n OHCA<\/jats:styled-content>\n patients (age \u226518\u00a0years) who achieved prehospital return of spontaneous circulation. Data were prospectively recorded in a nationwide, Japanese database between 2011 and 2012. The time from\n CPR<\/jats:styled-content>\n initiation to prehospital return of spontaneous circulation (\n CPR<\/jats:styled-content>\n duration) was calculated. The primary end point was 1\u2010month survival with favorable neurological outcomes (Cerebral Performance Category [\n CPC<\/jats:styled-content>\n ] scale;\n CPC<\/jats:styled-content>\n 1\u20132). The 1\u2010month\n CPC<\/jats:styled-content>\n 1\u20132 rate was 21.8% (n=3771).\n CPR<\/jats:styled-content>\n duration was inversely associated with 1\u2010month\n CPC<\/jats:styled-content>\n 1\u20132 (adjusted unit odds ratio: 0.95, 95%\n CI<\/jats:styled-content>\n : 0.94\u20130.95). Among all patients, a cumulative proportion of >99% of 1\u2010month\n CPC<\/jats:styled-content>\n 1\u20132 was achieved with a\n CPR<\/jats:styled-content>\n duration of 35\u00a0minutes. When sorted by the initial rhythm, the\n CPR<\/jats:styled-content>\n duration producing more than 99% of survivors with\n CPC<\/jats:styled-content>\n 1\u20132 was 35\u00a0minutes for shockable rhythms and pulseless electrical activity, and 42\u00a0minutes for asystole.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n CPR<\/jats:styled-content>\n duration was independently and inversely associated with favorable 1\u2010month neurological outcomes. The critical prehospital\n CPR<\/jats:styled-content>\n duration for\n OHCA<\/jats:styled-content>\n was 35\u00a0minutes in patients with initial shockable rhythms and pulseless electrical activity, and 42\u00a0minutes in those with initial asystole.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1161\/jaha.115.002819","type":"journal-article","created":{"date-parts":[[2016,3,19]],"date-time":"2016-03-19T00:15:57Z","timestamp":1458346557000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":164,"title":["Relationship Between the Duration of Cardiopulmonary Resuscitation and Favorable Neurological Outcomes After Out\u2010of\u2010Hospital Cardiac Arrest: A Prospective, Nationwide, Population\u2010Based Cohort Study"],"prefix":"10.1161","volume":"5","author":[{"given":"Yoshikazu","family":"Goto","sequence":"first","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, Kanazawa University Hospital, Kanazawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Funada","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, Kanazawa University Hospital, Kanazawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumiko","family":"Goto","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Yawata Medical Center, Komatsu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2015-007626"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.009711"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.010633"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.109496"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60958-7"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2006.07.020"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/cc9976"},{"key":"e_1_3_3_9_2","first-page":"III\u20101","article-title":"International Liaison Committee on Resuscitation: 2005 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations","volume":"112","year":"2005","unstructured":"International Liaison Committee on Resuscitation: 2005 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. 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