{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T16:25:07Z","timestamp":1792686307161,"version":"4.5.0"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2016,4,3]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      The goal of this study was to determine the prevalence of atrial fibrillation and atrial flutter (\n                      <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\n                      ) in pregnant women and to examine the impact of\n                      <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\n                      on maternal and fetal outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      Between January 1, 2003 and December 31, 2013, there were 264\u00a0730 qualifying pregnancies (in 210\u00a0356 women) in the Kaiser Permanente Southern California hospitals, among whom\n                      <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\n                      was noted in 157 pregnancies (129 women; 61.3 per 100\u00a0000 women, or 59.3 per 100\u00a0000 pregnancies). Prevalence of\n                      <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\n                      (per 100\u00a0000 women) in white, black, Asian, and Hispanic women was 111.6, 101.7, 45.0, and 34.3, respectively. Older age was associated with higher odds of having\n                      <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\n                      . Compared to women &lt;25\u00a0years of age, the odds ratio (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      ) of\n                      <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\n                      was 4.1 in women age 30 to 34\u00a0years, 4.9 in women age 35 to 39\u00a0years, and 5.2 in women age \u226540. Odds of\n                      <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\n                      episodes were higher during the third trimester compared to the first trimester (\n                      <jats:styled-content style=\"fixed-case\">OR<\/jats:styled-content>\n                      , 3.2; 95%\n                      <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n                      : 1.5\u20137.7). Among\n                      <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\n                      patients, adverse maternal cardiac events were rare\u20142 women developed heart failure and there were no strokes or systemic embolic events and no maternal death. There were 156 live births (99.4% of all pregnancies). Compared to women without\n                      <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\n                      , fetal birth weights were similar, but rate for neonates\u2019 admission to the neonatal intensive care unit was higher (10.8% vs 5.1%;\n                      <jats:italic>P<\/jats:italic>\n                      =0.003).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\n                      is rare in pregnant women. Certain factors such as increased maternal age and white race increase the odds of having\n                      <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\n                      . Major maternal and fetal complications are infrequent, albeit a source of concern.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.115.003182","type":"journal-article","created":{"date-parts":[[2016,4,14]],"date-time":"2016-04-14T01:49:30Z","timestamp":1460598570000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":72,"title":["Atrial Fibrillation and Atrial Flutter in Pregnant Women\u2014A Population\u2010Based Study"],"prefix":"10.1161","volume":"5","author":[{"given":"Ming\u2010Sum","family":"Lee","sequence":"first","affiliation":[{"name":"Division of Cardiology, Kaiser Permanente Medical Center, Los Angeles, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wansu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zilu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lewei","family":"Duan","sequence":"additional","affiliation":[{"name":"Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angie","family":"Ng","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Kaiser Permanente Medical Center, Los Angeles, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hillard T.","family":"Spencer","sequence":"additional","affiliation":[{"name":"Southern California Permanente Medical Group, Los Angeles, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damon M.","family":"Kwan","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Kaiser Permanente Medical Center, Los Angeles, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Albert Y.\u2010J.","family":"Shen","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Kaiser Permanente Medical Center, Los Angeles, 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