{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,29]],"date-time":"2026-05-29T23:38:20Z","timestamp":1780097900494,"version":"3.54.0"},"reference-count":39,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2016,10,3]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">The effect of a subsequent treated shockable rhythm during cardiopulmonary resuscitation on the outcome of children who suffer out\u2010of\u2010hospital cardiac arrest with initial nonshockable rhythm is unclear. We hypothesized that subsequent treated shockable rhythm in children with out\u2010of\u2010hospital cardiac arrest would improve survival with favorable neurological outcomes (Cerebral Performance Category scale 1\u20132).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              From the All\u2010Japan Utstein Registry, we analyzed the records of 12\u00a0402 children (aged &lt;18\u00a0years) with out\u2010of\u2010hospital cardiac arrest and initial nonshockable rhythms. Patients were divided into 2 cohorts: subsequent treated shockable rhythm (\n              <jats:styled-content style=\"fixed-case\">YES<\/jats:styled-content>\n              ; n=239) and subsequent treated shockable rhythm (\n              <jats:styled-content style=\"fixed-case\">NO<\/jats:styled-content>\n              ; n=12\u00a0163). The rate of 1\u2010month cerebral performance category 1 to 2 in the subsequent treated shockable rhythm (\n              <jats:styled-content style=\"fixed-case\">YES<\/jats:styled-content>\n              ) cohort was significantly higher when compared to the subsequent treated shockable rhythm (\n              <jats:styled-content style=\"fixed-case\">NO<\/jats:styled-content>\n              ) cohort (4.6% [11 of 239] vs 1.3% [155 of 12\u00a0163]; adjusted odds ratio, 2.90; 95% CI, 1.42\u20135.36; all\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001). In the subsequent treated shockable rhythm (\n              <jats:styled-content style=\"fixed-case\">YES<\/jats:styled-content>\n              ) cohort, the rate of 1\u2010month cerebral performance category 1 to 2 decreased significantly as time to shock delivery increased (17.7% [3 of 17] for patients with shock\u2010delivery time 0\u20139\u00a0minutes, 7.3% [8 of 109] for 10\u201319\u00a0minutes, and 0% [0 of 109] for 20\u201359\u00a0minutes;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001 [for trend]). Age\u2010stratified outcomes showed no significant differences between the 2 cohorts in the group aged &lt;7\u00a0years old: 1.3% versus 1.4%,\n              <jats:italic>P<\/jats:italic>\n              =0.62.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">In children with out\u2010of\u2010hospital cardiac arrest and initial nonshockable rhythms, subsequent treated shockable rhythm was associated with improved 1\u2010month survival with favorable neurological outcomes. In the cohort of older children (7\u201317\u00a0years), these outcomes worsened as time to shock delivery increased.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.116.003589","type":"journal-article","created":{"date-parts":[[2016,10,18]],"date-time":"2016-10-18T20:15:06Z","timestamp":1476821706000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":10,"title":["Subsequent Shockable Rhythm During Out\u2010of\u2010Hospital Cardiac Arrest in Children With Initial Non\u2010Shockable Rhythms: A Nationwide Population\u2010Based Observational Study"],"prefix":"10.1161","volume":"5","author":[{"given":"Yoshikazu","family":"Goto","sequence":"first","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, Kanazawa University Hospital, Kanazawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Funada","sequence":"additional","affiliation":[{"name":"Department of Emergency and Critical Care Medicine, Kanazawa University Hospital, Kanazawa, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumiko","family":"Goto","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Yawata Medical Center, Komatsu, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2015.08.021"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2007.03.008"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.802678"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2009.11.022"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2010.04.029"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.11.054"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e31827129b3"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2014.03.044"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/MCC.0b013e32832931e1"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1186\/cc13951"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000265"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/cir.0000000000000266"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2015.07.028"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2700.66526"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2013.11.015"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa052917"},{"key":"e_1_3_3_18_2","unstructured":"Ministry of Education Culture Sports Science and Technology of Japan\/Ministry of Health Labor and Welfare of Japan . 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