{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,17]],"date-time":"2026-01-17T19:17:22Z","timestamp":1768677442479,"version":"3.49.0"},"reference-count":42,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2016,7,6]]},"abstract":"\n Background<\/jats:title>\n Although patients with kidney disease have potential to benefit from revascularization, they are also at higher risk of complications, which may affect quality of life.<\/jats:p>\n <\/jats:sec>\n \n Methods and Results<\/jats:title>\n \n We studied a cohort of 8198 adults who underwent coronary angiography in Alberta, between 2004 and 2008, and completed health\u2010related quality\u2010of\u2010life (\n HR<\/jats:styled-content>\n \u2010\n QOL<\/jats:styled-content>\n ) surveys. Changes in\n HR<\/jats:styled-content>\n \u2010\n QOL<\/jats:styled-content>\n measures were most favorable among patients who received coronary artery bypass graft (\n CABG<\/jats:styled-content>\n ), but did not significantly differ by kidney function within groups of patients who received\n CABG<\/jats:styled-content>\n , percutaneous coronary intervention (\n PCI<\/jats:styled-content>\n ), or medical therapy (\n P<\/jats:italic>\n value for interaction between estimated glomerular filtration rate [\n eGFR<\/jats:styled-content>\n ] and revascularization status >0.10 for all outcomes). Among those who received\n CABG<\/jats:styled-content>\n , the adjusted mean EuroQol 5 dimensions (\n EQ<\/jats:styled-content>\n \u20105D) utility score for those with\n eGFR<\/jats:styled-content>\n >90\u00a0mL\/min per 1.73 m\n 2<\/jats:sup>\n increased by 0.11 (95%\n CI<\/jats:styled-content>\n , 0.09\u20130.14) and for those with\n eGFR<\/jats:styled-content>\n <30\u00a0mL\/min per 1.73m\n 2<\/jats:sup>\n by 0.13 (95%\n CI<\/jats:styled-content>\n , 0.05\u20130.21). The adjusted mean\n EQ<\/jats:styled-content>\n \u20105D utility score also increased similarly at all levels of\n eGFR<\/jats:styled-content>\n for those who received\n PCI<\/jats:styled-content>\n and for those who received medical management. Mean changes in Seattle Angina Questionnaire (\n SAQ<\/jats:styled-content>\n ) scores were also similar across all levels of\n eGFR<\/jats:styled-content>\n within each treatment group for the quality of life, angina frequency, angina stability, physical limitations, and treatment satisfaction domains of the\n SAQ<\/jats:styled-content>\n . Among those who received\n CABG<\/jats:styled-content>\n , the adjusted mean\n SAQ<\/jats:styled-content>\n quality of life score for those with\n eGFR<\/jats:styled-content>\n >90\u00a0mL\/min per 1.73m\n 2<\/jats:sup>\n increased by 22.1 (95%\n CI<\/jats:styled-content>\n , 18.5\u201325.7) and for those with\n eGFR<\/jats:styled-content>\n <30\u00a0mL\/min per 1.73m\n 2<\/jats:sup>\n by 14.0 (95% CI, 2.31\u201325.63).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Changes in\n HR<\/jats:styled-content>\n \u2010\n QOL<\/jats:styled-content>\n do not vary by kidney function among patients selected for\n CABG<\/jats:styled-content>\n ,\n PCI<\/jats:styled-content>\n , or medical management of coronary disease.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1161\/jaha.116.003642","type":"journal-article","created":{"date-parts":[[2016,7,20]],"date-time":"2016-07-20T01:38:12Z","timestamp":1468978692000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Kidney Function Does Not Modify the Favorable Quality of Life Changes Associated With Revascularization for Coronary Artery Disease: Cohort Study"],"prefix":"10.1161","volume":"5","author":[{"given":"Matthew T.","family":"James","sequence":"first","affiliation":[{"name":"Department of Medicine, Cumming School of Medicine, University of Calgary, Alberta, Canada"},{"name":"Department of Community Health Sciences, University of Calgary, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen B.","family":"Wilton","sequence":"additional","affiliation":[{"name":"Department of Cardiac Sciences, Cumming School of Medicine, University of Calgary, Alberta, 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