{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T10:40:57Z","timestamp":1779878457698,"version":"3.53.1"},"reference-count":41,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              Recent trials have demonstrated that extended cardiac monitoring increases the yield of paroxysmal atrial fibrillation (\n              <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\n              ) detection in patients with cryptogenic stroke. The utility of extended cardiac monitoring is uncertain among patients with stroke caused by small and large vessel disease. We conducted a meta\u2010analysis to estimate the yield of\n              <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\n              detection in this population.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              We searched PubMed, Cochrane, and\n              <jats:styled-content style=\"fixed-case\">SCOPUS<\/jats:styled-content>\n              databases for studies on\n              <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\n              detection in stroke patients and excluded studies restricted to patients with cryptogenic stroke or transient ischemic attack. We abstracted\n              <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\n              detection rates for 3 populations grouped by stroke etiology: large vessel stroke, small vessel stroke, and stroke of undefined etiology (a mixture of cryptogenic, small vessel, large vessel, and other stroke etiologies). Our search yielded 30 studies (n=5687).\n              <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\n              detection rates were similar in patients with large vessel (2.2%, 95%\n              <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n              0.3\u20135.5; n=830) and small vessel stroke (2.4%, 95%\n              <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n              0.4\u20136.1; n=520). No studies had a monitoring duration longer than 7\u00a0days. The yield of\n              <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\n              detection in the undefined stroke population was higher (9.2%; 95%\n              <jats:styled-content style=\"fixed-case\">CI<\/jats:styled-content>\n              7.1\u201311.5) compared to small vessel stroke (\n              <jats:italic>P<\/jats:italic>\n              =0.02) and large vessel stroke (\n              <jats:italic>P<\/jats:italic>\n              =0.02) populations.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\n              detection rate is similar in patients with small and large vessel strokes (2.2\u20132.4%). Because no studies reported on extended monitoring (&gt;7\u00a0days) in these stroke populations, we could not estimate the yield of\n              <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\n              detection with long\u2010term cardiac monitoring. Randomized controlled trials are needed to examine the utility of\n              <jats:styled-content style=\"fixed-case\">AF<\/jats:styled-content>\n              detection with long\u2010term cardiac monitoring (&gt;7\u00a0days) in this patient population.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.116.004151","type":"journal-article","created":{"date-parts":[[2016,9,27]],"date-time":"2016-09-27T02:59:43Z","timestamp":1474945183000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":22,"title":["Detection of Atrial Fibrillation Among Patients With Stroke Due to Large or Small Vessel Disease: A Meta\u2010Analysis"],"prefix":"10.1161","volume":"5","author":[{"given":"Jelle","family":"Demeestere","sequence":"first","affiliation":[{"name":"Department of Neurology, University Hospitals Leuven, Leuven, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steffen","family":"Fieuws","sequence":"additional","affiliation":[{"name":"Interuniversitary Institute for Biostatistics and Statistical Bio\u2010information, KU Leuven\u2013University of Leuven &amp; Universiteit Hasselt, Leuven, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maarten G.","family":"Lansberg","sequence":"additional","affiliation":[{"name":"Stanford Stroke Center, Stanford University of Medicine, Stanford, CA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin","family":"Lemmens","sequence":"additional","affiliation":[{"name":"KU Leuven\u2013University of Leuven, Department of Neurosciences Experimental Neurology and Leuven Research Institute for Neuroscience and Disease (LIND), Leuven, Belgium"},{"name":"VIB, Vesalius Research Center Laboratory of Neurobiology, Leuven, Belgium"},{"name":"University Hospitals Leuven, Department of Neurology, Leuven, Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1160\/TH11-02-0061"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.110.609297"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000040"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-146-12-200706190-00007"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)62343-0"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.112.654954"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1311376"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1313600"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000097"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/0197-2456(86)90046-2"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/sim.2971"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2004.01.004"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1444-0903.2004.00589.x"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.2007.00823.x"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2010.05.006"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2011.12.022"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.113.001884"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/ene.12198"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2013.08.003"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ihj.2014.02.009"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1540-8159.1999.tb00574.x"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000131269.69502.d9"},{"key":"e_1_3_4_24_2","first-page":"27","article-title":"Diagnostic and therapeutic impact of ambulatory electrocardiography in acute stroke","volume":"104","author":"Vandenbroucke E","year":"2004","unstructured":"Vandenbroucke E, Thijs VN. 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