{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T18:35:19Z","timestamp":1793298919693,"version":"4.5.0"},"reference-count":38,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:sec xml:lang=\"en\">\n                    <jats:title>Background<\/jats:title>\n                    <jats:p xml:lang=\"en\">Preeclampsia is a severe pregnancy disorder often complicated by reduced fetal growth or preterm delivery and is associated with long\u2010term maternal morbidity and mortality. We aimed to assess the association between preeclampsia phenotypes and risk of subsequent coronary heart disease and maternal cardiovascular mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Methods and Results<\/jats:title>\n                    <jats:p xml:lang=\"en\">\n                      Women aged 16 to 49\u00a0years who gave birth during 1980\u20132002 and registered in the Medical Birth Registry of Norway were followed prospectively (1\u201329\u00a0years) for an incident major coronary event and mortality through linkage with the Cardiovascular Disease in Norway 1994\u20132009 (\n                      <jats:styled-content style=\"fixed-case\">CVDNOR<\/jats:styled-content>\n                      ) project and the Norwegian Cause of Death Registry. Preeclampsia was subdivided based on the presence of a child born small for gestational age or preterm delivery. Among 506\u00a0350 women with 1 to 5 singleton births, there were 1275 (0.3%) occurrences of major coronary event, 468 (0.1%) cardiovascular deaths, and 5411 (1.1%) deaths overall. Compared with women without preeclampsia, the hazard ratio (95% CI) for major coronary event was 2.1 (1.73\u20132.65) after preeclampsia alone, 3.3 (2.37\u20134.57) after preeclampsia in combination with small for gestational age, and 5.4 (3.74\u20137.74) after preeclampsia in combination with preterm delivery. Analyses distinguishing women with 1 (n=61\u00a0352) or &gt;1 (n=281\u00a0069) lifetime pregnancy and analyses with cardiovascular mortality as outcome followed the same pattern.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec xml:lang=\"en\">\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p xml:lang=\"en\">The occurrence of major coronary events was increased among women with preeclampsia and highest for preeclampsia combined with a child born small for gestational age and\/or preterm delivery.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1161\/jaha.116.004158","type":"journal-article","created":{"date-parts":[[2017,3,6]],"date-time":"2017-03-06T20:25:48Z","timestamp":1488831948000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":90,"title":["Incident Coronary Heart Disease After Preeclampsia: Role of Reduced Fetal Growth, Preterm Delivery, and Parity"],"prefix":"10.1161","volume":"6","author":[{"given":"Hilde Kristin Refvik","family":"Riise","sequence":"first","affiliation":[{"name":"Department of Global Public Health and Primary Care University of Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerhard","family":"Sulo","sequence":"additional","affiliation":[{"name":"Department of Global Public Health and Primary Care University of Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grethe S.","family":"Tell","sequence":"additional","affiliation":[{"name":"Department of Global Public Health and Primary Care University of Bergen Norway"},{"name":"Department of Health Registries Norwegian Institute of Public Health Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jannicke","family":"Igland","sequence":"additional","affiliation":[{"name":"Department of Global Public Health and Primary Care University of Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ottar","family":"Nyg\u00e5rd","sequence":"additional","affiliation":[{"name":"KG Jebsen Center for Diabetes Research Department of Clinical Science University of Bergen Norway"},{"name":"Department of Heart Disease Haukeland University Hospital Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stein Emil","family":"Vollset","sequence":"additional","affiliation":[{"name":"Department of Global Public Health and Primary Care University of Bergen Norway"},{"name":"Centre for Disease Burden Norwegian Institute of Public Health Oslo\/Bergen Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ann\u2010Charlotte","family":"Iversen","sequence":"additional","affiliation":[{"name":"Department of Cancer Research and Molecular Medicine Centre of Molecular Inflammation Research Norwegian University of Science and Technology (NTNU) Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rigmor","family":"Austgulen","sequence":"additional","affiliation":[{"name":"Department of Cancer Research and Molecular Medicine Centre of Molecular Inflammation Research Norwegian University of Science and Technology (NTNU) Trondheim Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne Kjersti","family":"Daltveit","sequence":"additional","affiliation":[{"name":"Department of Global Public Health and Primary Care University of Bergen Norway"},{"name":"Department of Health Registries Norwegian Institute of Public Health Bergen Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1053\/plac.2000.0560"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2000.tb11657.x"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2012.11.022"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2008.11.021"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1042\/CS20050323"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006254-200301000-00022"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.39335.385301.BE"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-013-9762-6"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.07.049"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.orcp.2015.05.008"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0033047"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.044784"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annepidem.2010.05.007"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.109.130765"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(00)05112-6"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2005.00733.x"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1080\/j.1600-0412.2000.079006435.x"},{"key":"e_1_3_2_19_2","first-page":"7","article-title":"Cardiovascular disease and diabetes mellitus in Norway during 1994\u20132009: CVDNOR\u2014a nationwide research project","volume":"23","author":"Sulo G","year":"2013","unstructured":"Sulo G, Igland J, Vollset SE, Nygaard O, Oyen N, Tell G. Cardiovascular disease and diabetes mellitus in Norway during 1994\u20132009: CVDNOR\u2014a nationwide research project. Nor Epidemiol. 2013;23:7.","journal-title":"Nor Epidemiol"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-011-2281-7"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1979.03290450033020"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2000.107928"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.1111\/aogs.12159"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.1080\/j.1600-0412.2000.079006440.x"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.b5087"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0000000000000696"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.003901"},{"key":"e_1_3_2_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2013.09.020"},{"key":"e_1_3_2_29_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2008.11.003"},{"key":"e_1_3_2_30_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000053441.43495.1A"},{"key":"e_1_3_2_31_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.e7677"},{"key":"e_1_3_2_32_2","doi-asserted-by":"publisher","DOI":"10.1080\/14034940510032383"},{"key":"e_1_3_2_33_2","doi-asserted-by":"publisher","DOI":"10.1093\/epirev\/mxt006"},{"key":"e_1_3_2_34_2","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/30.6.1317"},{"key":"e_1_3_2_35_2","doi-asserted-by":"publisher","DOI":"10.1093\/ije\/dyn167"},{"key":"e_1_3_2_36_2","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.24.4.683"},{"key":"e_1_3_2_37_2","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.82.6.816"},{"key":"e_1_3_2_38_2","doi-asserted-by":"publisher","DOI":"10.1093\/epirev\/mxm001"},{"key":"e_1_3_2_39_2","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.113.300156"}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.116.004158","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T06:26:07Z","timestamp":1715581567000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.116.004158"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,3]]},"references-count":38,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2017,3]]}},"alternative-id":["10.1161\/JAHA.116.004158"],"URL":"https:\/\/doi.org\/10.1161\/jaha.116.004158","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,3]]},"assertion":[{"value":"2016-07-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-01-31","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-03-06","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e004158"}}