{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T00:21:29Z","timestamp":1788999689160,"version":"build-2803163510"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:sec id=\"jah31907-sec-0001\" xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              The high burden of undetected and undertreated hypertension and diabetes mellitus is a major health challenge worldwide. The\n              <jats:styled-content style=\"fixed-case\" toggle=\"no\">mP<\/jats:styled-content>\n              ower Heart Project aimed to develop and test a feasible and scalable intervention for hypertension and diabetes mellitus by task\u2010sharing with the use of a mobile phone\u2013based clinical decision support system at Community Health Centers in Himachal Pradesh, India.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec id=\"jah31907-sec-0002\" xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              The development of the intervention and mobile phone\u2013based clinical decision support system was carried out using mixed methods in five Community Health Centers. The intervention was subsequently evaluated using pre\u2013post evaluation design. During intervention, a nurse care coordinator screened, examined, and entered patient parameters into mobile phone\u2013based clinical decision support system to generate a prescription, which was vetted by a physician. The change in systolic blood pressure, diastolic blood pressure, and fasting plasma glucose (\n              <jats:styled-content style=\"fixed-case\" toggle=\"no\">FPG<\/jats:styled-content>\n              ) over 18\u00a0months of intervention was quantified using generalized estimating equations models. During intervention, 6797 participants were enrolled. Six thousand sixteen participants had hypertension (mean systolic blood pressure: 146.1\u00a0mm\u00a0Hg, 95%\n              <jats:styled-content style=\"fixed-case\" toggle=\"no\">CI<\/jats:styled-content>\n              : 145.7, 146.5; diastolic blood pressure: 89.52\u00a0mm\u00a0Hg, 95%\n              <jats:styled-content style=\"fixed-case\" toggle=\"no\">CI<\/jats:styled-content>\n              : 89.33, 89.72), of which 3152 (52%) subjects were newly detected. Similarly, 1516 participants had diabetes mellitus (mean\n              <jats:styled-content style=\"fixed-case\" toggle=\"no\">FPG<\/jats:styled-content>\n              : 177.9\u00a0mg\/dL, 95%\n              <jats:styled-content style=\"fixed-case\" toggle=\"no\">CI<\/jats:styled-content>\n              : 175.8, 180.0), of which 450 (30%) subjects were newly detected. The changes in systolic blood pressure, diastolic blood pressure, and\n              <jats:styled-content style=\"fixed-case\" toggle=\"no\">FPG<\/jats:styled-content>\n              observed at 18\u00a0months of follow\u2010up were \u221214.6\u00a0mm\u00a0Hg (95%\n              <jats:styled-content style=\"fixed-case\" toggle=\"no\">CI<\/jats:styled-content>\n              : \u221215.3, \u221213.8), \u22127.6\u00a0mm\u00a0Hg (\n              <jats:styled-content style=\"fixed-case\" toggle=\"no\">CI<\/jats:styled-content>\n              : \u22128.0, \u22127.2), and \u221250.0\u00a0mg\/dL (95%\n              <jats:styled-content style=\"fixed-case\" toggle=\"no\">CI<\/jats:styled-content>\n              : \u221254.6, \u221245.5), respectively, and were statistically significant even after adjusting for age, sex, and Community Health Center.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec id=\"jah31907-sec-0003\" xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">A nurse\u2010facilitated, mobile phone\u2013based clinical decision support system\u2010enabled intervention in primary care was associated with improvements in blood pressure and blood glucose control and has the potential to scale\u2010up in resource poor settings.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec id=\"jah31907-sec-0004\" xml:lang=\"en\">\n            <jats:title>Clinical Trial Registration<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              <jats:styled-content style=\"fixed-case\" toggle=\"no\">URL<\/jats:styled-content>\n              :\n              <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.clinicaltrials.gov\">https:\/\/www.clinicaltrials.gov<\/jats:ext-link>\n              . Unique identifiers:\n              <jats:styled-content style=\"fixed-case\" toggle=\"no\">NCT<\/jats:styled-content>\n              01794052. Clinical Trial Registry\u2014India:\n              <jats:styled-content style=\"fixed-case\" toggle=\"no\">CTRI<\/jats:styled-content>\n              \/2013\/02\/003412.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.116.004343","type":"journal-article","created":{"date-parts":[[2016,12,22]],"date-time":"2016-12-22T01:31:39Z","timestamp":1482370299000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":75,"title":["Development of a Smartphone\u2010Enabled Hypertension and Diabetes Mellitus Management Package to Facilitate Evidence\u2010Based Care Delivery in Primary Healthcare Facilities in India: The mPower Heart Project"],"prefix":"10.1161","volume":"5","author":[{"given":"Vamadevan S.","family":"Ajay","sequence":"first","affiliation":[{"name":"Centre for Chronic Disease Control (CCDC)","place":["New Delhi, India"]},{"name":"Public Health Foundation of India (PHFI)","place":["Gurgaon, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devraj","family":"Jindal","sequence":"additional","affiliation":[{"name":"Centre for Chronic Disease Control (CCDC)","place":["New Delhi, India"]},{"name":"Public Health Foundation of India (PHFI)","place":["Gurgaon, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ambuj","family":"Roy","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences","place":["New Delhi, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vidya","family":"Venugopal","sequence":"additional","affiliation":[{"name":"Centre for Chronic Disease Control (CCDC)","place":["New Delhi, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rakshit","family":"Sharma","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences","place":["New Delhi, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abha","family":"Pawar","sequence":"additional","affiliation":[{"name":"Centre for Chronic Disease Control (CCDC)","place":["New Delhi, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Kinra","sequence":"additional","affiliation":[{"name":"London School of Hygiene & Tropical Medicine","place":["London, United Kingdom"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nikhil","family":"Tandon","sequence":"additional","affiliation":[{"name":"All India Institute of Medical Sciences","place":["New Delhi, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorairaj","family":"Prabhakaran","sequence":"additional","affiliation":[{"name":"Centre for Chronic Disease Control (CCDC)","place":["New Delhi, India"]},{"name":"Public Health Foundation of India (PHFI)","place":["Gurgaon, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_2_2_2","unstructured":"Institute of Health Metrics and Evaluation University of Washington . 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