{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:54:56Z","timestamp":1787018096288,"version":"build-2736575974"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2017,4,5]]},"abstract":"\n Background<\/jats:title>\n \n Smoking cessation and weight management are recommended after acute coronary syndrome (\n ACS<\/jats:styled-content>\n ); however, little is known about the effects of smoking cessation on weight change after\n ACS<\/jats:styled-content>\n . We aimed to assess the effect of smoking cessation after\n ACS<\/jats:styled-content>\n on weight over a 12\u2010month follow\u2010up period.\n <\/jats:p>\n <\/jats:sec>\n \n Methods and Results<\/jats:title>\n \n Data were prospectively collected from the EVITA (Evaluation of Varenicline in Smoking Cessation for Patients Post\u2010Acute Coronary Syndrome) trial. Weight change was compared among 3 groups of patients: those who were completely abstinent (n=70), those who smoked intermittently (n=68), and those who smoked persistently (n=34). Patients' mean baseline weight was 83.9\u00a0kg (\n SD<\/jats:styled-content>\n 17.7) with a mean body mass index of 28.5 (\n SD<\/jats:styled-content>\n 5.4). Patients smoked a mean of 37.7\u00a0years (\n SD<\/jats:styled-content>\n 17.7) and a mean of 21.0 cigarettes (\n SD<\/jats:styled-content>\n 9.0) per day prior to their\n ACS<\/jats:styled-content>\n . Weight change varied across groups, with abstainers gaining a mean of 4.8\u00a0kg (\n SD<\/jats:styled-content>\n 8.6), intermittent smokers gaining a mean of 2.0\u00a0kg (\n SD<\/jats:styled-content>\n 8.9) and persistent smokers losing a mean of 0.7\u00a0kg (\n SD<\/jats:styled-content>\n 7.4). At 52\u00a0weeks, abstainers were more likely to gain weight than persistent smokers (difference in means 5.5\u00a0kg; 95%\n CI<\/jats:styled-content>\n 2.3\u20138.8). This weight gain was not associated with an increase in the use of antihypertensive or antidiabetic medications.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Following an\n ACS<\/jats:styled-content>\n , significant weight is gained by patients who quit smoking. Weight\u2010management interventions among smokers who quit after\n ACS<\/jats:styled-content>\n should be a focus of investigation in future research so that the cardiovascular benefits achieved by smoking cessation are not offset by weight gain in this high\u2010risk population.\n <\/jats:p>\n <\/jats:sec>\n \n Clinical Trial Registration<\/jats:title>\n \n URL<\/jats:styled-content>\n :\n http:\/\/www.clinicaltrials.gov<\/jats:ext-link>\n . Unique identifier:\n NCT<\/jats:styled-content>\n 00794573.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1161\/jaha.116.004785","type":"journal-article","created":{"date-parts":[[2017,4,18]],"date-time":"2017-04-18T20:50:14Z","timestamp":1492548614000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Smokers and Postcessation Weight Gain After Acute Coronary Syndrome"],"prefix":"10.1161","volume":"6","author":[{"given":"Payam","family":"Dehghani","sequence":"first","affiliation":[{"name":"Prairie Vascular Research Network, University of Saskatchewan, Regina, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bettina","family":"Habib","sequence":"additional","affiliation":[{"name":"Division of Clinical Epidemiology, Lady Davis Institute, Jewish General Hospital\/McGill University, Montr\u00e9al, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah B.","family":"Windle","sequence":"additional","affiliation":[{"name":"Division of Clinical Epidemiology, Lady Davis Institute, Jewish General Hospital\/McGill University, Montr\u00e9al, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathalie","family":"Roy","sequence":"additional","affiliation":[{"name":"Centre de sant\u00e9 et de services sociaux de Chicoutimi, Chicoutimi, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne","family":"Old","sequence":"additional","affiliation":[{"name":"Sentara Cardiovascular Research Institute, Norfolk, VA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois R.","family":"Grondin","sequence":"additional","affiliation":[{"name":"CISSS Chaudi\u00e8re\u2010Appalaches, H\u00f4tel\u2010Dieu de L\u00e9vis site, L\u00e9vis, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iqbal","family":"Bata","sequence":"additional","affiliation":[{"name":"Queen Elizabeth II Health Sciences Centre, Halifax, Nova Scotia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayman","family":"Iskander","sequence":"additional","affiliation":[{"name":"SJH Cardiology Associates and St. Joseph's Hospital, Liverpool, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claude","family":"Lauzon","sequence":"additional","affiliation":[{"name":"CISSS \u2010 Chaudi\u00e8re\u2010Appalaches, Thetford Mines, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nalin","family":"Srivastava","sequence":"additional","affiliation":[{"name":"Spartanburg Regional Medical Center, Spartanburg, SC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Clarke","sequence":"additional","affiliation":[{"name":"Valley Regional Hospital, Kentville, Nova Scotia, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel","family":"Cassavar","sequence":"additional","affiliation":[{"name":"ProMedica Toledo Hospital, Toledo, OH"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Dion","sequence":"additional","affiliation":[{"name":"CISSS de Chaudi\u00e8re Appalaches site H\u00f4pital St\u2010Georges, Beauce, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Herbert","family":"Haught","sequence":"additional","affiliation":[{"name":"Heart Center Research, Huntsville, AL"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shamir R.","family":"Mehta","sequence":"additional","affiliation":[{"name":"Hamilton Health Sciences, Hamilton, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean\u2010Fran\u00e7ois","family":"Baril","sequence":"additional","affiliation":[{"name":"Dr. Georges\u2010L.\u2010Dumont 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