{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T04:41:09Z","timestamp":1771994469402,"version":"3.50.1"},"reference-count":41,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2017,3]]},"abstract":"\n Background<\/jats:title>\n \n Right bundle branch block is an established predictor for new conduction disturbances and need for a permanent pacemaker (\n PPM<\/jats:styled-content>\n ) after transcatheter aortic valve replacement. The aim of the study was to evaluate the absolute rates of transcatheter aortic valve replacement related\n PPM<\/jats:styled-content>\n implantations in patients with pre\u2010existent right bundle branch block and categorize for different transcatheter heart valves.\n <\/jats:p>\n <\/jats:sec>\n \n Methods and Results<\/jats:title>\n \n We pooled data on 306 transcatheter aortic valve replacement patients from 4 high\u2010volume centers in Europe and selected those with right bundle branch block at baseline without a previously implanted\n PPM<\/jats:styled-content>\n . Logistic regression was used to evaluate whether\n PPM<\/jats:styled-content>\n rate differed among transcatheter heart valves after adjustment for confounders. Mean age was 83\u00b17\u00a0years and 63% were male. Median Society of Thoracic Surgeons score was 6.3 (interquartile range, 4.1\u201310.2). The following transcatheter valve designs were used: Medtronic CoreValve (n=130; Medtronic, Minneapolis, MN); Edwards Sapien\n XT<\/jats:styled-content>\n (\n ES<\/jats:styled-content>\n \u2010\n XT<\/jats:styled-content>\n ; n=124) and Edwards Sapien 3 (\n ES<\/jats:styled-content>\n \u20103; n=32; Edwards Lifesciences, Irvine, CA); and Boston Scientific Lotus (n=20; Boston Scientific Corporation, Marlborough, MA). Overall permanent pacemaker implantation rate post\u2010transcatheter aortic valve replacement was 41%, and per valve design: 75% with Lotus, 46% with CoreValve, 32% with\n ES<\/jats:styled-content>\n \u2010\n XT<\/jats:styled-content>\n , and 34% with\n ES<\/jats:styled-content>\n \u20103. The indication for\n PPM<\/jats:styled-content>\n implantation was total atrioventricular block in 98% of the cases. Lotus was associated with a higher\n PPM<\/jats:styled-content>\n rate than all other valves.\n PPM<\/jats:styled-content>\n rate did not differ between\n ES<\/jats:styled-content>\n \u2010\n XT<\/jats:styled-content>\n and\n ES<\/jats:styled-content>\n \u20103. Ventricular paced rhythm at 30\u2010day and 1\u2010year follow\u2010up was present in 81% at 89%, respectively.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Right bundle branch block at baseline is associated with a high incidence of\n PPM<\/jats:styled-content>\n implantation for all transcatheter heart valves.\n PPM<\/jats:styled-content>\n rate was highest for Lotus and lowest for\n ES<\/jats:styled-content>\n \u2010\n XT<\/jats:styled-content>\n and\n ES<\/jats:styled-content>\n \u20103. Pacemaker dependency remained high during follow\u2010up.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1161\/jaha.116.005028","type":"journal-article","created":{"date-parts":[[2017,3,4]],"date-time":"2017-03-04T02:00:39Z","timestamp":1488592839000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":32,"title":["Transcatheter Heart Valve Selection and Permanent Pacemaker Implantation in Patients With Pre\u2010Existent Right Bundle Branch Block"],"prefix":"10.1161","volume":"6","author":[{"given":"Lennart","family":"van Gils","sequence":"first","affiliation":[{"name":"Erasmus Medical Center Rotterdam The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Didier","family":"Tchetche","sequence":"additional","affiliation":[{"name":"Clinique Pasteur Toulouse 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