{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T08:27:37Z","timestamp":1773131257722,"version":"3.50.1"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"7","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2017,7]]},"abstract":"\n Background<\/jats:title>\n \n Cardiac arrest (\n CA<\/jats:styled-content>\n ) is a leading cause of death in the United States, claiming over 450\u00a0000 lives annually. Improving survival depends on the ability to conduct\n CA<\/jats:styled-content>\n research and on the translation and implementation of research findings into practice. Our objective was to provide a descriptive analysis of annual National Institutes of Health (\n NIH<\/jats:styled-content>\n ) funding for\n CA<\/jats:styled-content>\n research over the past decade.\n <\/jats:p>\n <\/jats:sec>\n \n Method and Results<\/jats:title>\n \n A search within\n NIH<\/jats:styled-content>\n Re\n PORTER<\/jats:styled-content>\n for the years 2007 to 2016 was performed using the terms: \u201ccardiac arrest\u201d or \u201ccardiopulmonary resuscitation\u201d or \u201cheart arrest\u201d or \u201ccirculatory arrest\u201d or \u201cpulseless electrical activity\u201d or \u201cventricular fibrillation\u201d or \u201cresuscitation.\u201d Grants were reviewed and categorized as\n CA<\/jats:styled-content>\n research (yes\/no) using predefined criteria. The annual\n NIH<\/jats:styled-content>\n funding for\n CA<\/jats:styled-content>\n research, number of individual grants, and principal investigators were tabulated. The total\n NIH<\/jats:styled-content>\n investment in\n CA<\/jats:styled-content>\n research for 2015 was calculated and compared to those for other leading causes of death within the United States. Interrater reliability among 3 independent reviewers for fiscal year 2015 was assessed using Fleiss \u03ba. The search yielded 2763\n NIH<\/jats:styled-content>\n \u2010funded grants, of which 745 (27.0%) were classified as\n CA<\/jats:styled-content>\n research (\u03ba=0.86 [95%\n CI<\/jats:styled-content>\n 0.80\u20100.93]). Total inflation\u2010adjusted\n NIH<\/jats:styled-content>\n funding for\n CA<\/jats:styled-content>\n research was $35.4\u00a0million in 2007, peaked at $76.7\u00a0million in 2010, and has decreased to $28.5\u00a0million in 2016. Per annual death,\n NIH<\/jats:styled-content>\n invests \u2248$2200 for stroke, \u2248$2100 for heart disease, and \u2248$91 for CA.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n This analysis demonstrates that the annual\n NIH<\/jats:styled-content>\n investment in CA research is low relative to other leading causes of death in the United States and has declined over the past decade.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1161\/jaha.116.005239","type":"journal-article","created":{"date-parts":[[2017,7,13]],"date-time":"2017-07-13T00:10:32Z","timestamp":1499904632000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":36,"title":["National Institutes of Health\u2013Funded Cardiac Arrest Research: A 10\u2010Year Trend Analysis"],"prefix":"10.1161","volume":"6","author":[{"given":"Ryan A.","family":"Coute","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, University of Michigan, Ann Arbor, MI"},{"name":"Kansas City University of Medicine and Biosciences, Kansas City, MO"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashish R.","family":"Panchal","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Ohio State University, Columbus, OH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy J.","family":"Mader","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Baystate Medical Center, University of Massachusetts Medical School\u2010Baystate, Springfield, MA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert W.","family":"Neumar","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, University of Michigan, Ann Arbor, MI"},{"name":"Michigan Center for Integrative Research in Critical Care, University of Michigan, Ann Arbor, MI"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.emc.2011.09.003"},{"key":"e_1_3_5_3_2","volume-title":"Strategies to Improve Cardiac Arrest Survival: A Time to Act","author":"Institute of Medicine of the National Academies","year":"2015","unstructured":"Institute of Medicine of the National Academies . Strategies to Improve Cardiac Arrest Survival: A Time to Act. Washington, DC: National Academies Press; 2015."},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000485"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.114.000925"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3182257459"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.963991"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.116.002916"},{"key":"e_1_3_5_9_2","unstructured":"NIH RePORTER. National Institutes of Health. Available at: https:\/\/projectreporter.nih.gov\/reporter.cfm. Accessed October 3 2016."},{"key":"e_1_3_5_10_2","unstructured":"Centers for Disease Control and Prevention . Health United States 2015 Table\u00a019. Available at: http:\/\/www.cdc.gov\/nchs\/data\/hus\/hus15.pdf#019. Accessed October 3 2016."},{"key":"e_1_3_5_11_2","unstructured":"Research Condition and Disease Category (RCDC) . National Institutes of Health Categorical Spending. Available at: https:\/\/report.nih.gov\/categorical_spending.aspx. Accessed October 3 2016."},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1161\/cir.0000000000000152"},{"key":"e_1_3_5_13_2","unstructured":"Consumer Price Index Inflation Calculator. United States Department of Labor. Available at: https:\/\/data.bls.gov\/cgi-bin\/cpicalc.pl. Accessed January 29 2017."},{"key":"e_1_3_5_14_2","volume-title":"Statistical Methods for Rates and Proportions","author":"Fleiss JL","year":"2013","unstructured":"Fleiss JL, Levin B, Paik MC. Statistical Methods for Rates and Proportions. Hoboken, NJ: John Wiley & Sons; 2013."},{"key":"e_1_3_5_15_2","unstructured":"NIH Research Grants: Awards and Total Funding by Type and NIH Institutes\/Centers. Table\u00a0102. National Institutes of Health. Available at: https:\/\/report.nih.gov\/budget_and_spending\/index.aspx. Accessed October 3 2016."}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.116.005239","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T10:30:36Z","timestamp":1715596236000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.116.005239"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7]]},"references-count":14,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2017,7]]}},"alternative-id":["10.1161\/JAHA.116.005239"],"URL":"https:\/\/doi.org\/10.1161\/jaha.116.005239","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,7]]},"assertion":[{"value":"2016-12-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-05-04","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-07-12","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e005239"}}