{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T23:25:42Z","timestamp":1791588342788,"version":"4.3.4"},"reference-count":53,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2017,4,5]]},"abstract":"\n Background<\/jats:title>\n \n The association between obesity and mortality risks following coronary revascularization is not clear. We examined the associations of BMI (kg\/m\n 2<\/jats:sup>\n ) with short\u2010, intermediate\u2010, and long\u2010term mortality following coronary artery bypass graft surgery (\n CABG<\/jats:styled-content>\n ) and percutaneous coronary intervention (\n PCI<\/jats:styled-content>\n ) in patients with different coronary anatomy risks and diabetes mellitus status.\n <\/jats:p>\n <\/jats:sec>\n \n Methods and Results<\/jats:title>\n \n Data from the Alberta Provincial Project for Outcomes Assessment in Coronary Heart Disease (APPROACH) registry were analyzed. Using normal\n BMI<\/jats:styled-content>\n (18.5\u201324.9) as a reference, multivariable\u2010adjusted hazard ratios for all\u2010cause mortality within 6\u00a0months, 1\u00a0year, 5\u00a0years, and 10\u00a0years were individually calculated for\n CABG<\/jats:styled-content>\n and\n PCI<\/jats:styled-content>\n with 4 prespecified\n BMI<\/jats:styled-content>\n categories: overweight (25.0\u201329.9), obese class I (30.0\u201334.9), obese class\n II<\/jats:styled-content>\n (35.0\u201339.9), and obese class\n III<\/jats:styled-content>\n (\u226540.0). The analyses were repeated after stratifying for coronary risks and diabetes mellitus status. The cohorts included 7560 and 30\u00a0258 patients for\n CABG<\/jats:styled-content>\n and\n PCI<\/jats:styled-content>\n , respectively. Following\n PCI<\/jats:styled-content>\n , overall mortality was lower in patients with overweight and obese class I compared to those with normal\n BMI<\/jats:styled-content>\n ; however, 5\u2010 and 10\u2010year mortality rates were significantly higher in patients with obese class\n III<\/jats:styled-content>\n with high\u2010risk coronary anatomy, which was primarily driven by higher mortality rates in patients without diabetes mellitus (5\u2010year adjusted hazard ratio, 1.78 [95%\n CI<\/jats:styled-content>\n , 1.11\u20132.85] and 10\u2010year adjusted hazard ratio, 1.57 [95% CI, 1.02\u20132.43]). Following\n CABG<\/jats:styled-content>\n , overweight was associated with lower mortality risks compared with normal\n BMI<\/jats:styled-content>\n .\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Overweight was associated with lower mortality following\n CABG<\/jats:styled-content>\n and\n PCI<\/jats:styled-content>\n . Greater long\u2010term mortality in patients with obese class\n III<\/jats:styled-content>\n following\n PCI<\/jats:styled-content>\n , especially in those with high\u2010risk coronary anatomy without diabetes mellitus, warrants further investigation.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1161\/jaha.116.005335","type":"journal-article","created":{"date-parts":[[2017,4,15]],"date-time":"2017-04-15T00:20:10Z","timestamp":1492215610000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":28,"title":["Differences in Short\u2010 and Long\u2010Term Mortality Associated With BMI Following Coronary Revascularization"],"prefix":"10.1161","volume":"6","author":[{"given":"Tasuku","family":"Terada","sequence":"first","affiliation":[{"name":"Department of Occupational Therapy, Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Forhan","sequence":"additional","affiliation":[{"name":"Department of Occupational Therapy, Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Colleen M.","family":"Norris","sequence":"additional","affiliation":[{"name":"School of Public Health, University of Alberta, Edmonton, Alberta, Canada"},{"name":"Faculty of Nursing, University of Alberta, Edmonton, Alberta, Canada"},{"name":"Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada"},{"name":"Alberta Transplant Institute, University of Alberta, Edmonton, Alberta, Canada"},{"name":"Cardiovascular Health and Stroke Strategic Clinical Network, Alberta Health Services, Edmonton, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiyu","family":"Qiu","sequence":"additional","affiliation":[{"name":"School of Public Health, University of Alberta, Edmonton, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raj","family":"Padwal","sequence":"additional","affiliation":[{"name":"Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arya M.","family":"Sharma","sequence":"additional","affiliation":[{"name":"Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayan","family":"Nagendran","sequence":"additional","affiliation":[{"name":"Alberta Transplant Institute, University of Alberta, Edmonton, Alberta, Canada"},{"name":"Department of Surgery, Mazankowski Alberta Heart Institute, Alberta Health Services, Edmonton, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey A.","family":"Johnson","sequence":"additional","affiliation":[{"name":"School of Public Health, University of Alberta, Edmonton, Alberta, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.050806"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.9778\/cmajo.20130016"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0025-6196(11)61175-0"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.2298\/VSP1401027C"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000442015.53336.12"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2010.06.052"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1000367"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2007.36"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)69251-9"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2014.04.020"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2014-307119"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(02)01969-1"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(99)00143-5"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.09.057"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(98)00467-7"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.94.8.1818"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)00823-8"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1067\/mtc.2003.73"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezw138"},{"key":"e_1_3_3_21_2","unstructured":"World Health Organization . 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