{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T23:41:22Z","timestamp":1777678882446,"version":"3.51.4"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2017,10,11]]},"abstract":"<jats:sec xml:lang=\"en\">\n            <jats:title>Background<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              Participation in cardiac rehabilitation (\n              <jats:styled-content style=\"fixed-case\">CR<\/jats:styled-content>\n              ) is an essential component of care for patients with coronary artery disease. However, little is known about its benefit on cardiovascular outcomes in patients with diabetes mellitus (\n              <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n              ) who have undergone percutaneous coronary intervention. The aim of our study was to evaluate the impact of\n              <jats:styled-content style=\"fixed-case\">CR<\/jats:styled-content>\n              in this high\u2010risk group of patients.\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Methods and Results<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              We performed a retrospective analysis of all patients with\n              <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n              who underwent percutaneous coronary intervention in Olmsted County (Minnesota) between 1994 and 2010, assessing the impact of\n              <jats:styled-content style=\"fixed-case\">CR<\/jats:styled-content>\n              participation on clinical outcomes.\n              <jats:styled-content style=\"fixed-case\">CR<\/jats:styled-content>\n              participation was significantly lower in patients with\n              <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n              (38%, 263\/700) compared with those who did not have\n              <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n              (45%, 1071\/2379;\n              <jats:italic>P<\/jats:italic>\n              =0.004). Using propensity score adjustment, we found that in patients with\n              <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n              ,\n              <jats:styled-content style=\"fixed-case\">CR<\/jats:styled-content>\n              participation was associated with significantly reduced all\u2010cause mortality (hazard ratio, 0.56; 95% confidence interval, 0.39\u20130.80;\n              <jats:italic>P<\/jats:italic>\n              =0.002) and composite end point of mortality, myocardial infarction, or revascularization (hazard ratio, 0.77; 95% confidence interval, 0.60\u20130.98;\n              <jats:italic>P<\/jats:italic>\n              =0.037), during a median follow\u2010up of 8.1\u00a0years. In patients without\n              <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n              ,\n              <jats:styled-content style=\"fixed-case\">CR<\/jats:styled-content>\n              participation was associated with a significant reduction in all\u2010cause mortality (hazard ratio, 0.67; 95% confidence interval, 0.55\u20130.82;\n              <jats:italic>P<\/jats:italic>\n              &lt;0.001) and cardiac mortality (hazard ratio, 0.67; 95% confidence interval, 0.47\u20130.95;\n              <jats:italic>P<\/jats:italic>\n              =0.024).\n            <\/jats:p>\n          <\/jats:sec>\n          <jats:sec xml:lang=\"en\">\n            <jats:title>Conclusions<\/jats:title>\n            <jats:p xml:lang=\"en\">\n              <jats:styled-content style=\"fixed-case\">CR<\/jats:styled-content>\n              participation after percutaneous coronary intervention is associated with lower all\u2010cause mortality rates in patients with\n              <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n              , to a similar degree as for those without\n              <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n              . However,\n              <jats:styled-content style=\"fixed-case\">CR<\/jats:styled-content>\n              participation was lower in patients with\n              <jats:styled-content style=\"fixed-case\">DM<\/jats:styled-content>\n              , suggesting the need to identify and correct the barriers to\n              <jats:styled-content style=\"fixed-case\">CR<\/jats:styled-content>\n              participation for this higher\u2010risk group of patients.\n            <\/jats:p>\n          <\/jats:sec>","DOI":"10.1161\/jaha.117.006404","type":"journal-article","created":{"date-parts":[[2017,10,12]],"date-time":"2017-10-12T00:10:20Z","timestamp":1507767020000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":32,"title":["Benefits of Cardiac Rehabilitation on Cardiovascular Outcomes in Patients With Diabetes Mellitus After Percutaneous Coronary Intervention"],"prefix":"10.1161","volume":"6","author":[{"given":"Manuel F.","family":"Jim\u00e9nez\u2010Navarro","sequence":"first","affiliation":[{"name":"UGC Coraz\u00f3n, Hospital Universitario Virgen de la Victoria, Instituto de Biomedicina de M\u00e1laga, CIBERCV Enfermedades Cardiovasculares, Universidad de M\u00e1laga, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Lopez\u2010Jimenez","sequence":"additional","affiliation":[{"name":"The Department of Cardiovascular Diseases and Department of Health Sciences Research, Mayo Clinic, Rochester, MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis M.","family":"P\u00e9rez\u2010Belmonte","sequence":"additional","affiliation":[{"name":"UGC Coraz\u00f3n, Hospital Universitario Virgen de la Victoria, Instituto de Biomedicina de M\u00e1laga, CIBERCV Enfermedades Cardiovasculares, Universidad de M\u00e1laga, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan J.","family":"Lennon","sequence":"additional","affiliation":[{"name":"The Department of Cardiovascular Diseases and Department of Health Sciences Research, Mayo Clinic, Rochester, MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Diaz\u2010Melean","sequence":"additional","affiliation":[{"name":"The Department of Cardiovascular Diseases and Department of Health Sciences Research, Mayo Clinic, Rochester, MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. P.","family":"Rodriguez\u2010Escudero","sequence":"additional","affiliation":[{"name":"The Department of Cardiovascular Diseases and Department of Health Sciences Research, Mayo Clinic, Rochester, MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kashish","family":"Goel","sequence":"additional","affiliation":[{"name":"The Department of Cardiovascular Diseases and Department of Health Sciences Research, Mayo Clinic, Rochester, MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Crusan","sequence":"additional","affiliation":[{"name":"The Department of Cardiovascular Diseases and Department of Health Sciences Research, Mayo Clinic, Rochester, MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abhiram","family":"Prasad","sequence":"additional","affiliation":[{"name":"The Department of Cardiovascular Diseases and Department of Health Sciences Research, Mayo Clinic, Rochester, MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ray W.","family":"Squires","sequence":"additional","affiliation":[{"name":"The Department of Cardiovascular Diseases and Department of Health Sciences Research, Mayo Clinic, Rochester, MN"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Randal J.","family":"Thomas","sequence":"additional","affiliation":[{"name":"The Department of Cardiovascular Diseases and Department of Health Sciences Research, Mayo Clinic, Rochester, MN"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.12.001"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.983536"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.112.001365"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.HCR.0000320068.35728.12"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)60679-X"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000441139.02102.80"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/cir.0000000000000152"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1097\/HCR.0b013e31823be0bc"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/HCR.0b013e3181c565fe"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.01.066"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-1241.2001.tb11088.x"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-5491.2004.01262.x"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabres.2014.11.006"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2003.09.017"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1177\/1741826710393993"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.1002\/clc.22245"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-015-3491-1"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.01.078"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(01)01236-0"},{"key":"e_1_3_4_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcnurse.2004.11.003"},{"key":"e_1_3_4_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2008.01.030"},{"key":"e_1_3_4_23_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1988.03410070073031"},{"key":"e_1_3_4_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2008.12.021"},{"key":"e_1_3_4_25_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.02.063"},{"key":"e_1_3_4_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2015.03.521"},{"key":"e_1_3_4_27_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2008.553"},{"key":"e_1_3_4_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2004.05.062"},{"key":"e_1_3_4_29_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199910283411806"}],"container-title":["Journal of the American Heart Association"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ahajournals.org\/doi\/full\/10.1161\/JAHA.117.006404","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,13]],"date-time":"2024-05-13T10:47:41Z","timestamp":1715597261000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ahajournals.org\/doi\/10.1161\/JAHA.117.006404"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,11]]},"references-count":28,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2017,10,11]]}},"alternative-id":["10.1161\/JAHA.117.006404"],"URL":"https:\/\/doi.org\/10.1161\/jaha.117.006404","relation":{},"ISSN":["2047-9980"],"issn-type":[{"value":"2047-9980","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,11]]},"assertion":[{"value":"2017-04-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-08-14","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-10-11","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"e006404"}}