{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:34:57Z","timestamp":1787240097621,"version":"build-2736575974"},"reference-count":61,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2017,10,11]]},"abstract":"\n Background<\/jats:title>\n \n More than 60% of patients decline participation in cardiac rehabilitation after a myocardial infarction. Options to improve physical activity (\n PA<\/jats:styled-content>\n ) and other risk factors in these high\u2010risk individuals are limited. We conducted a phase 2 randomized controlled trial to determine feasibility, safety, acceptability, and estimates of effect of tai chi on\n PA<\/jats:styled-content>\n , fitness, weight, and quality of life.\n <\/jats:p>\n <\/jats:sec>\n \n Methods and Results<\/jats:title>\n \n Patients with coronary heart disease declining cardiac rehabilitation enrollment were randomized to a \u201c\n LITE<\/jats:styled-content>\n \u201d (2 sessions\/week for 12\u00a0weeks) or to a \u201c\n PLUS<\/jats:styled-content>\n \u201d (3 sessions\/week for 12\u00a0weeks, then maintenance classes for 12 additional weeks) condition.\n PA<\/jats:styled-content>\n (accelerometry), weight, and quality of life (Health Survey Short Form) were measured at baseline and 3, 6, and 9\u00a0months after baseline; aerobic fitness (stress test) was measured at 3\u00a0months. Twenty\u2010nine participants (13\n PLUS<\/jats:styled-content>\n and 16\n LITE<\/jats:styled-content>\n ) were enrolled. Retention at 9\u00a0months was 90% (\n LITE<\/jats:styled-content>\n ) and 88% (\n PLUS<\/jats:styled-content>\n ). No serious tai chi\u2013related adverse events occurred. Significant mean between group differences in favor of the\n PLUS<\/jats:styled-content>\n group were observed at 3 and 6\u00a0months for moderate\u2010to\u2010vigorous\n PA<\/jats:styled-content>\n (100.33 min\/week [95% confidence interval, 15.70\u2013184.95 min\/week] and 111.62 min\/week; [95% confidence interval, 26.17\u2013197.07 min\/week], respectively, with a trend toward significance at 9\u00a0months), percentage change in weight, and quality of life. No changes in aerobic fitness were observed within and between groups.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n In this community sample of patients with coronary heart disease declining enrollment in cardiac rehabilitation, a 6\u2010month tai chi program was safe and improved\n PA<\/jats:styled-content>\n , weight, and quality of life compared with a 3\u2010month intervention. Tai chi could be an effective option to improve PA in this high\u2010risk population.\n <\/jats:p>\n <\/jats:sec>\n \n Clinical Trial Registration<\/jats:title>\n \n URL<\/jats:styled-content>\n :\n http:\/\/www.clinicaltrials.gov<\/jats:ext-link>\n . Unique identifier:\n NCT<\/jats:styled-content>\n 02165254.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1161\/jaha.117.006603","type":"journal-article","created":{"date-parts":[[2017,10,11]],"date-time":"2017-10-11T20:10:20Z","timestamp":1507752620000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":46,"title":["Tai Chi Is a Promising Exercise Option for Patients With Coronary Heart Disease Declining Cardiac Rehabilitation"],"prefix":"10.1161","volume":"6","author":[{"given":"Elena","family":"Salmoirago\u2010Blotcher","sequence":"first","affiliation":[{"name":"The Miriam Hospital and The Warren Alpert Medical School of Brown University, Providence, RI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter M.","family":"Wayne","sequence":"additional","affiliation":[{"name":"Osher Center for Integrative Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shira","family":"Dunsiger","sequence":"additional","affiliation":[{"name":"The Miriam Hospital and The Warren Alpert Medical School of Brown University, Providence, RI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Krol","sequence":"additional","affiliation":[{"name":"The Miriam Hospital, Providence, RI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Breault","sequence":"additional","affiliation":[{"name":"The Miriam Hospital, Providence, RI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beth C.","family":"Bock","sequence":"additional","affiliation":[{"name":"The Miriam Hospital and The Warren Alpert Medical School of Brown University, Providence, RI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen\u2010Chih","family":"Wu","sequence":"additional","affiliation":[{"name":"The Miriam Hospital and The Warren Alpert Medical School of Brown University, Providence, RI"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gloria Y.","family":"Yeh","sequence":"additional","affiliation":[{"name":"Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.1322"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1093\/ehjqcco\/qcw003"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.12968\/bjon.2011.20.2.107"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.168.18.1961"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehl475"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000075572.40158.77"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.038422"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.292.10.1179"},{"key":"e_1_3_4_10_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.876383"},{"key":"e_1_3_4_11_2","first-page":"CD001800","article-title":"Exercise\u2010based cardiac rehabilitation for coronary heart disease","author":"Heran BS","year":"2011","unstructured":"Heran BS, Chen JM, Ebrahim S, Moxham T, Oldridge N, Rees K, Thompson DR, Taylor RS. 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