{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T13:22:36Z","timestamp":1762867356586,"version":"3.41.2"},"reference-count":37,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["www.ahajournals.org"],"crossmark-restriction":true},"short-container-title":["JAHA"],"published-print":{"date-parts":[[2018,2,20]]},"abstract":"\n Background<\/jats:title>\n \n There are limited data regarding the prognostic impact of angiographic complete revascularization (\n CR<\/jats:styled-content>\n ) in patients with chronic kidney disease (\n CKD<\/jats:styled-content>\n ). We sought to investigate the differential prognostic impact of angiographic\n CR<\/jats:styled-content>\n over incomplete revascularization (\n IR<\/jats:styled-content>\n ), according to the presence of\n CKD<\/jats:styled-content>\n in the drug\u2010eluting stent era.\n <\/jats:p>\n <\/jats:sec>\n \n Methods and Results<\/jats:title>\n \n Between 2003 and 2011 at Samsung Medical Center, consecutive patients with multivessel disease were stratified by the presence of\n CKD<\/jats:styled-content>\n (estimated glomerular filtration rate <60\u00a0mL\/min per 1.73\u00a0m\n 2<\/jats:sup>\n ) and classified according to angiographic\n CR<\/jats:styled-content>\n (residual\n SYNTAX<\/jats:styled-content>\n score=0) or\n IR<\/jats:styled-content>\n . Clinical outcomes were compared between angiographic\n CR<\/jats:styled-content>\n and\n IR<\/jats:styled-content>\n , stratified by the presence of\n CKD<\/jats:styled-content>\n . Primary outcome was patient\u2010oriented composite outcomes (\n POCO<\/jats:styled-content>\n , a composite of all\u2010cause death, myocardial infarction, any revascularization) at 3 years. Inverse probability weighting was performed between the\n CR<\/jats:styled-content>\n and\n IR<\/jats:styled-content>\n groups. A total of 3224 patients were eligible for analysis: 2295 without\n CKD<\/jats:styled-content>\n ; 929 with\n CKD<\/jats:styled-content>\n . Among non\u2010\n CKD<\/jats:styled-content>\n patients, angiographic\n CR<\/jats:styled-content>\n showed a significantly lower risk of\n POCO<\/jats:styled-content>\n than\n IR<\/jats:styled-content>\n (17.2% versus 21.7%, adjusted hazard ratio 0.76, 95% confidence interval, 0.62\u20130.95,\n P<\/jats:italic>\n =0.014), mainly driven by a significantly lower risk of any revascularization. Among\n CKD<\/jats:styled-content>\n patients, however, angiographic\n CR<\/jats:styled-content>\n was associated with a significantly higher risk of\n POCO<\/jats:styled-content>\n than\n IR<\/jats:styled-content>\n (37.7% versus 28.4%, adjusted hazard ratio 1.42, 95% confidence interval, 1.08%\u20131.85%,\n P<\/jats:italic>\n =0.011), mainly driven by a significantly higher risk of nonfatal target vessel myocardial infarction.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n \n Angiographic\n CR<\/jats:styled-content>\n was associated with reduced risk of\n POCO<\/jats:styled-content>\n than\n IR<\/jats:styled-content>\n in patients without\n CKD<\/jats:styled-content>\n ; however, it was associated with a significantly higher risk of\n POCO<\/jats:styled-content>\n and nonfatal myocardial infarction in\n CKD<\/jats:styled-content>\n patients.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.1161\/jaha.117.007962","type":"journal-article","created":{"date-parts":[[2018,2,16]],"date-time":"2018-02-16T01:10:18Z","timestamp":1518743418000},"update-policy":"https:\/\/doi.org\/10.1161\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Differential Clinical Outcomes Between Angiographic Complete Versus Incomplete Coronary Revascularization, According to the Presence of Chronic Kidney Disease in the Drug\u2010Eluting Stent Era"],"prefix":"10.1161","volume":"7","author":[{"given":"Jihoon","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joo Myung","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ki Hong","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tae\u2010Min","family":"Rhee","sequence":"additional","affiliation":[{"name":"National Maritime Medical Center, Changwon, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Doyeon","family":"Hwang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and Cardiovascular Center, Seoul National University Hospital, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonghanne","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Naju National Hospital, Ministry of Health and Welfare, Naju, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chul","family":"Ahn","sequence":"additional","affiliation":[{"name":"Division of Biostatistics, Center for Devices and Radiological Health, Food and Drug Administration, Silver Spring, MD"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taek Kyu","family":"Park","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeong Hoon","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Bin","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin\u2010Ho","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joo\u2010Yong","family":"Hahn","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seung\u2010Hyuk","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Heart Vascular Stroke Institute, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, 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